Detailed information NTG1138878

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: DQM56_RS00740
• Genome accession: NZ_LS483368
• Coordinates: 126615..127568 (+)
• Length: 317 a.a.
• NCBI ID: WP_012514788.1
• Uniprot ID: B4U062
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC6176
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 121615..132568

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM56_RS00700 (NCTC6176_00140)	-	122090..122758 (+)	669	WP_043024949.1	ATP-binding cassette domain-containing protein	-
DQM56_RS00705 (NCTC6176_00141)	comGA/cglA	122914..123852 (+)	939	WP_111710107.1	competence type IV pilus ATPase ComGA	Machinery gene
DQM56_RS00710 (NCTC6176_00142)	comGB	123785..124818 (+)	1034	Protein_105	competence type IV pilus assembly protein ComGB	-
DQM56_RS00715 (NCTC6176_00143)	comGC/cglC	124819..125142 (+)	324	WP_012514782.1	competence type IV pilus major pilin ComGC	Machinery gene
DQM56_RS00720 (NCTC6176_00144)	comGD	125120..125545 (+)	426	WP_012514783.1	competence type IV pilus minor pilin ComGD	-
DQM56_RS00725 (NCTC6176_00145)	comGE	125550..125792 (+)	243	WP_207622334.1	competence type IV pilus minor pilin ComGE	-
DQM56_RS00730 (NCTC6176_00146)	comYF	125779..126213 (+)	435	WP_014622144.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQM56_RS00735 (NCTC6176_00147)	comGG	126191..126553 (+)	363	WP_012677238.1	competence type IV pilus minor pilin ComGG	-
DQM56_RS00740 (NCTC6176_00148)	comYH	126615..127568 (+)	954	WP_012514788.1	class I SAM-dependent methyltransferase	Machinery gene
DQM56_RS00745 (NCTC6176_00149)	-	127628..128827 (+)	1200	WP_111677653.1	acetate kinase	-
DQM56_RS00750 (NCTC6176_00150)	-	129199..129813 (-)	615	WP_021320266.1	hypothetical protein	-
DQM56_RS00755 (NCTC6176_00151)	-	130336..132378 (+)	2043	WP_111710109.1	BglG family transcription antiterminator	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 35736.74 Da
• Isoelectric Point: 4.6973

>NTDB_id=1138878 DQM56_RS00740 WP_012514788.1 126615..127568(+) (comYH) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
MNFEKIEQAYELILENSQLIENDLKTHIYDAIVEQNSFYLGAQGASPQVAKNIETLKALQLTKEEWRQAYQFVLIKAGKT
EPLQANHQFTPDAIGFIMLYILETLSSQESLDVLEIGSGTGNLAQTILNHSHKSIDYLGIELDDLLIDLSASIAEIMGSS
AQFIQEDAVRPQLLKESDLIISDLPVGFYPNDDIASRYQVASSDEHTYAHHLLMEQALKYLKKDGFAIFLAPVNLLSSPQ
SHLLKQWLKGYAQVVALITLPEAVFGNPANAKSIIVLCKQSNRFAETFVYPIRDLKSVDNVRDFMENFKNWKRDNVI

Nucleotide

• Length: 954 bp

>NTDB_id=1138878 DQM56_RS00740 WP_012514788.1 126615..127568(+) (comYH) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
ATGAATTTTGAAAAGATTGAACAAGCCTATGAGCTTATATTAGAAAATAGCCAGCTGATTGAAAATGATCTAAAAACGCA
TATCTATGATGCTATTGTTGAGCAGAATTCTTTTTATCTGGGAGCCCAAGGAGCAAGCCCTCAGGTTGCTAAAAATATTG
AGACGTTGAAGGCCTTGCAGCTAACCAAGGAGGAGTGGCGTCAGGCTTATCAGTTTGTTTTGATCAAGGCTGGGAAAACA
GAGCCATTACAGGCCAACCACCAATTTACCCCAGACGCGATCGGCTTTATCATGCTTTATATTTTGGAGACCTTGAGTTC
ACAAGAGTCACTTGATGTGCTTGAGATTGGCAGTGGAACAGGTAATCTAGCTCAAACTATTTTAAACCATTCACATAAGA
GCATTGATTATTTAGGCATTGAGCTTGATGATTTACTAATTGATCTATCAGCTAGTATCGCTGAAATCATGGGGTCATCA
GCCCAGTTTATTCAAGAGGATGCTGTCAGACCTCAGCTGTTAAAAGAAAGTGATCTCATCATTAGCGATTTGCCAGTTGG
TTTTTATCCTAACGACGATATTGCTAGCAGGTATCAGGTGGCTAGCTCAGATGAGCATACCTATGCCCATCATTTACTGA
TGGAGCAAGCCTTAAAGTACCTGAAAAAAGATGGCTTTGCTATTTTCTTAGCACCGGTAAATCTTTTGAGCAGCCCACAA
AGTCACCTCTTAAAACAATGGCTGAAGGGCTATGCTCAGGTTGTGGCCTTGATTACTTTGCCTGAGGCTGTGTTTGGAAA
TCCAGCTAATGCAAAATCGATTATTGTTCTTTGTAAGCAATCGAATCGCTTTGCAGAAACCTTTGTTTACCCCATTAGGG
ATTTGAAATCTGTTGATAATGTTCGTGATTTTATGGAAAACTTCAAAAATTGGAAACGGGATAATGTTATTTAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (68-294)

3D structure

• AlphaFold DB: B4U062

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA159	63.608	99.685	0.634
comYH	Streptococcus mutans UA140	63.608	99.685	0.634