Detailed information NTG1138137

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: DQL13_RS00720
• Genome accession: NZ_LS483354
• Coordinates: 124045..124368 (+)
• Length: 107 a.a.
• NCBI ID: WP_012514782.1
• Uniprot ID: B4U056
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC11606
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 119045..129368

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL13_RS00695	-	119052..119243 (+)	192	Protein_104	lactococcin 972 family bacteriocin	-
DQL13_RS00700 (NCTC11606_00140)	-	119308..121311 (+)	2004	WP_111721612.1	DUF1430 domain-containing protein	-
DQL13_RS00705 (NCTC11606_00141)	-	121313..121981 (+)	669	WP_012514779.1	ATP-binding cassette domain-containing protein	-
DQL13_RS00710 (NCTC11606_00142)	comGA/cglA	122139..123077 (+)	939	WP_012514780.1	competence type IV pilus ATPase ComGA	Machinery gene
DQL13_RS00715 (NCTC11606_00143)	comYB	123010..124044 (+)	1035	WP_228275455.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQL13_RS00720 (NCTC11606_00144)	comGC/cglC	124045..124368 (+)	324	WP_012514782.1	competence type IV pilus major pilin ComGC	Machinery gene
DQL13_RS00725 (NCTC11606_00145)	comGD	124346..124771 (+)	426	WP_012514783.1	competence type IV pilus minor pilin ComGD	-
DQL13_RS00730 (NCTC11606_00146)	comGE	124776..125018 (+)	243	WP_012677236.1	competence type IV pilus minor pilin ComGE	-
DQL13_RS00735 (NCTC11606_00147)	comYF	125005..125439 (+)	435	WP_037580631.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQL13_RS00740 (NCTC11606_00148)	comGG	125417..125779 (+)	363	WP_012514785.1	competence type IV pilus minor pilin ComGG	-
DQL13_RS00750 (NCTC11606_00151)	comYH	127273..128226 (+)	954	WP_012514788.1	class I SAM-dependent methyltransferase	Machinery gene

Sequence

Protein

• Length: 107 a.a.
• Molecular weight: 12149.19 Da
• Isoelectric Point: 8.4057

>NTDB_id=1138137 DQL13_RS00720 WP_012514782.1 124045..124368(+) (comGC/cglC) [Streptococcus equi subsp. zooepidemicus strain NCTC11606]
MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKDKVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQE
DGSISDKQQKAYQDYYAKHKDEAKKLN

Nucleotide

• Length: 324 bp

>NTDB_id=1138137 DQL13_RS00720 WP_012514782.1 124045..124368(+) (comGC/cglC) [Streptococcus equi subsp. zooepidemicus strain NCTC11606]
ATGAAAATGAGATTATCAATCTTAAAAGATCAAGGTGTTCAGGCCTTCACTTTACTGGAAATGCTTCTGGTTTTATTAAT
CATTAGTGTTTTAATGCTGTTATTTGTTCCAAATTTAAGTAAACAAAAGGATAAGGTGACAGACACAGGCAATGCTGCAG
TGGTAAAGCTAGTTGAAAATCAGGCAGAGCTTTATGAATTATCACATGGGGAAAAGCCAAGCCTGAAGCAGCTGCAAGAG
GATGGAAGTATCAGTGACAAGCAGCAAAAGGCTTATCAGGATTATTATGCAAAGCATAAAGATGAAGCTAAGAAGCTCAA
TTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (14-34)

3D structure

• AlphaFold DB: B4U056

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis SK321	59.813	100	0.598
comGC/cglC	Streptococcus pneumoniae Rx1	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae D39	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae R6	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae TIGR4	57.944	100	0.579
comYC	Streptococcus gordonii str. Challis substr. CH1	62.245	91.589	0.57
comGC/cglC	Streptococcus mitis NCTC 12261	61.616	92.523	0.57
comYC	Streptococcus mutans UA140	58.763	90.654	0.533
comYC	Streptococcus mutans UA159	58.763	90.654	0.533
comGC	Lactococcus lactis subsp. cremoris KW2	56.842	88.785	0.505
comYC	Streptococcus suis isolate S10	60	74.766	0.449
comGC	Staphylococcus aureus MW2	50	72.897	0.364
comGC	Staphylococcus aureus N315	50	72.897	0.364