Detailed information    

insolico Bioinformatically predicted

Overview


Name   ssbA   Type   Machinery gene
Locus tag   DQL37_RS08995 Genome accession   NZ_LS483352
Coordinates   1725611..1726003 (+) Length   130 a.a.
NCBI ID   WP_032460876.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12052     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1710461..1748205 1725611..1726003 within 0


Gene organization within MGE regions


Location: 1710461..1748205
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL37_RS08885 (NCTC12052_01753) groL 1710461..1712092 (-) 1632 WP_002982320.1 chaperonin GroEL -
  DQL37_RS08890 (NCTC12052_01754) groES 1712128..1712418 (-) 291 WP_002991292.1 co-chaperone GroES -
  DQL37_RS08895 (NCTC12052_01755) clpC 1712596..1715040 (-) 2445 WP_111685848.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  DQL37_RS08900 (NCTC12052_01756) - 1715040..1715501 (-) 462 WP_002982312.1 CtsR family transcriptional regulator -
  DQL37_RS08905 - 1715697..1715900 (-) 204 WP_002991299.1 cold-shock protein -
  DQL37_RS08910 (NCTC12052_01758) - 1716499..1717569 (-) 1071 WP_063629765.1 tyrosine-type recombinase/integrase -
  DQL37_RS08915 (NCTC12052_01759) - 1717697..1717999 (-) 303 WP_111685849.1 hypothetical protein -
  DQL37_RS08920 (NCTC12052_01760) - 1717992..1718378 (-) 387 WP_063629763.1 ImmA/IrrE family metallo-endopeptidase -
  DQL37_RS08925 (NCTC12052_01761) - 1718382..1718732 (-) 351 WP_063629762.1 helix-turn-helix domain-containing protein -
  DQL37_RS08935 (NCTC12052_01762) - 1719129..1719338 (+) 210 WP_111685850.1 helix-turn-helix domain-containing protein -
  DQL37_RS08940 (NCTC12052_01763) - 1719338..1719700 (+) 363 WP_063629760.1 hypothetical protein -
  DQL37_RS08945 (NCTC12052_01764) - 1719722..1720006 (+) 285 WP_063629759.1 hypothetical protein -
  DQL37_RS08950 (NCTC12052_01765) - 1720033..1720251 (+) 219 WP_063629758.1 hypothetical protein -
  DQL37_RS08955 (NCTC12052_01766) dnaB 1720260..1721606 (+) 1347 WP_111685851.1 replicative DNA helicase -
  DQL37_RS08960 (NCTC12052_01767) - 1721593..1722339 (+) 747 WP_111685852.1 conserved phage C-terminal domain-containing protein -
  DQL37_RS08965 (NCTC12052_01768) - 1722340..1723161 (+) 822 WP_111685853.1 ATP-binding protein -
  DQL37_RS08970 (NCTC12052_01769) - 1723161..1723388 (+) 228 WP_063629755.1 hypothetical protein -
  DQL37_RS09770 (NCTC12052_01770) - 1723402..1723572 (+) 171 WP_168388561.1 hypothetical protein -
  DQL37_RS08975 (NCTC12052_01771) - 1723569..1723838 (+) 270 WP_109982045.1 hypothetical protein -
  DQL37_RS08980 (NCTC12052_01772) - 1723841..1724590 (+) 750 WP_111685854.1 DNA-methyltransferase -
  DQL37_RS08985 (NCTC12052_01773) - 1724638..1725384 (+) 747 WP_231907105.1 DUF1642 domain-containing protein -
  DQL37_RS08990 (NCTC12052_01774) - 1725396..1725614 (+) 219 WP_111685855.1 hypothetical protein -
  DQL37_RS08995 (NCTC12052_01775) ssbA 1725611..1726003 (+) 393 WP_032460876.1 single-stranded DNA-binding protein Machinery gene
  DQL37_RS09000 (NCTC12052_01776) - 1726017..1726295 (+) 279 WP_029713970.1 hypothetical protein -
  DQL37_RS09010 (NCTC12052_01778) - 1726390..1726617 (+) 228 WP_063629751.1 hypothetical protein -
  DQL37_RS09015 (NCTC12052_01779) - 1726589..1727053 (+) 465 WP_063629750.1 hypothetical protein -
  DQL37_RS09020 (NCTC12052_01780) - 1727163..1727705 (+) 543 WP_063629749.1 site-specific integrase -
  DQL37_RS09025 (NCTC12052_01781) - 1727875..1728057 (+) 183 WP_063629748.1 hypothetical protein -
  DQL37_RS09920 - 1728446..1728640 (+) 195 WP_227876734.1 HNH endonuclease -
  DQL37_RS09035 (NCTC12052_01782) - 1728758..1729243 (+) 486 WP_000601034.1 hypothetical protein -
  DQL37_RS09040 (NCTC12052_01783) - 1729236..1730948 (+) 1713 WP_111685857.1 terminase TerL endonuclease subunit -
  DQL37_RS09045 (NCTC12052_01784) - 1730957..1732099 (+) 1143 WP_111685858.1 phage portal protein -
  DQL37_RS09050 (NCTC12052_01785) - 1732150..1732692 (+) 543 WP_063629746.1 HK97 family phage prohead protease -
  DQL37_RS09055 (NCTC12052_01786) - 1732703..1733965 (+) 1263 WP_063629745.1 phage major capsid protein -
  DQL37_RS09060 (NCTC12052_01787) - 1733985..1734323 (+) 339 WP_032460894.1 hypothetical protein -
  DQL37_RS09065 (NCTC12052_01788) - 1734320..1734625 (+) 306 WP_032460893.1 head-tail adaptor protein -
  DQL37_RS09070 (NCTC12052_01789) - 1734625..1734972 (+) 348 WP_032460892.1 hypothetical protein -
  DQL37_RS09075 (NCTC12052_01790) - 1734959..1735303 (+) 345 WP_063629744.1 hypothetical protein -
  DQL37_RS09080 (NCTC12052_01791) - 1735318..1735989 (+) 672 WP_063629743.1 phage tail protein -
  DQL37_RS09085 (NCTC12052_01792) - 1735993..1736466 (+) 474 WP_063629742.1 hypothetical protein -
  DQL37_RS09095 (NCTC12052_01793) - 1736656..1739391 (+) 2736 WP_111685860.1 phage tail tape measure protein -
  DQL37_RS09100 (NCTC12052_01794) - 1739388..1740110 (+) 723 WP_063629740.1 hypothetical protein -
  DQL37_RS09105 (NCTC12052_01795) - 1740111..1742054 (+) 1944 WP_231907106.1 phage tail spike protein -
  DQL37_RS09110 (NCTC12052_01796) - 1742051..1743166 (+) 1116 WP_063629043.1 hyaluronoglucosaminidase -
  DQL37_RS09115 (NCTC12052_01797) - 1743181..1744962 (+) 1782 WP_111685861.1 gp58-like family protein -
  DQL37_RS09120 (NCTC12052_01798) - 1744971..1745399 (+) 429 WP_111685862.1 DUF1617 family protein -
  DQL37_RS09125 (NCTC12052_01799) - 1745402..1746040 (+) 639 WP_111685863.1 hypothetical protein -
  DQL37_RS09130 (NCTC12052_01800) - 1746050..1746322 (+) 273 WP_111685864.1 hypothetical protein -
  DQL37_RS09135 (NCTC12052_01801) - 1746319..1746546 (+) 228 WP_003058873.1 phage holin -
  DQL37_RS09140 (NCTC12052_01803) - 1746662..1747879 (+) 1218 WP_111685865.1 peptidoglycan amidohydrolase family protein -
  DQL37_RS10045 (NCTC12052_01804) prx 1748044..1748205 (+) 162 WP_309543630.1 hypothetical protein Regulator

Sequence


Protein


Download         Length: 130 a.a.        Molecular weight: 14837.69 Da        Isoelectric Point: 5.8648

>NTDB_id=1138069 DQL37_RS08995 WP_032460876.1 1725611..1726003(+) (ssbA) [Streptococcus pyogenes strain NCTC12052]
MINNVVLIGRLTKDVELRYTPSQVACAQFTLAVNRNFKNQDGQKEADFINCVMWRQAAENLTNWTKKGHLIAITGRIQTR
NYENQNGQRVYVTEVVAESFQILEKRDNTANTNSLADTMPDYGPEPDLPF

Nucleotide


Download         Length: 393 bp        

>NTDB_id=1138069 DQL37_RS08995 WP_032460876.1 1725611..1726003(+) (ssbA) [Streptococcus pyogenes strain NCTC12052]
ATGATCAATAACGTTGTCCTGATTGGCCGCTTAACAAAAGATGTTGAGCTACGCTATACACCAAGTCAAGTAGCTTGCGC
ACAGTTTACTTTAGCAGTTAATCGTAATTTTAAAAATCAAGATGGACAAAAAGAAGCTGATTTTATTAATTGTGTGATGT
GGCGACAAGCTGCTGAAAATTTAACAAATTGGACTAAGAAGGGCCATCTGATTGCGATAACAGGACGCATTCAGACCCGT
AACTATGAGAATCAGAATGGTCAACGTGTTTACGTGACAGAAGTGGTTGCCGAAAGTTTTCAAATTTTAGAGAAGCGTGA
TAATACAGCTAATACTAATAGCTTGGCAGATACCATGCCAGACTATGGACCAGAACCAGATTTACCATTTTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Bacillus subtilis subsp. subtilis str. 168

67.29

82.308

0.554

  ssb Latilactobacillus sakei subsp. sakei 23K

64.22

83.846

0.538

  ssbB Streptococcus sobrinus strain NIDR 6715-7

46.97

100

0.477

  ssbA Streptococcus mutans UA159

44.444

100

0.462

  ssbB/cilA Streptococcus pneumoniae TIGR4

44.697

100

0.454

  ssbB/cilA Streptococcus pneumoniae Rx1

43.939

100

0.446

  ssbB/cilA Streptococcus pneumoniae R6

43.939

100

0.446

  ssbB/cilA Streptococcus mitis SK321

43.939

100

0.446

  ssbB/cilA Streptococcus mitis NCTC 12261

43.939

100

0.446

  ssbB/cilA Streptococcus pneumoniae D39

43.939

100

0.446

  ssbB Bacillus subtilis subsp. subtilis str. 168

52.83

81.538

0.431

  ssbB Lactococcus lactis subsp. cremoris KW2

41.86

99.231

0.415


Multiple sequence alignment