Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DQL59_RS07415 Genome accession   NZ_LS483326
Coordinates   1464778..1465716 (-) Length   312 a.a.
NCBI ID   WP_002987773.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12045     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1459778..1470716
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL59_RS07375 (NCTC12045_01459) - 1459793..1460989 (-) 1197 WP_111681328.1 acetate kinase -
  DQL59_RS07380 (NCTC12045_01460) comYH 1461048..1462001 (-) 954 WP_111681329.1 class I SAM-dependent methyltransferase Machinery gene
  DQL59_RS07385 (NCTC12045_01461) comGG 1462099..1462425 (-) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  DQL59_RS07390 (NCTC12045_01462) comYF 1462409..1462843 (-) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL59_RS07395 (NCTC12045_01463) comGE 1462836..1463120 (-) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  DQL59_RS07400 (NCTC12045_01464) comGD 1463077..1463505 (-) 429 WP_111681330.1 competence type IV pilus minor pilin ComGD -
  DQL59_RS07405 (NCTC12045_01465) comYC 1463480..1463806 (-) 327 WP_111681331.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL59_RS07410 (NCTC12045_01466) comYB 1463808..1464842 (-) 1035 WP_227874808.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL59_RS07415 (NCTC12045_01467) comYA 1464778..1465716 (-) 939 WP_002987773.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL59_RS07420 (NCTC12045_01468) - 1465809..1466174 (-) 366 WP_002986560.1 DUF1033 family protein -
  DQL59_RS07425 (NCTC12045_01469) rpoC 1466326..1469967 (-) 3642 WP_111681333.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35046.30 Da        Isoelectric Point: 8.5799

>NTDB_id=1136648 DQL59_RS07415 WP_002987773.1 1464778..1465716(-) (comYA) [Streptococcus pyogenes strain NCTC12045]
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISSYHQEA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGITKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=1136648 DQL59_RS07415 WP_002987773.1 1464778..1465716(-) (comYA) [Streptococcus pyogenes strain NCTC12045]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTATTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTTAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAAGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAGTTATCATCAAGAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAAATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGCAAGATTGTTAGAACTTGGTATAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

61.736

99.679

0.615
  comYA Streptococcus mutans UA140

61.736

99.679

0.615
  comYA Streptococcus gordonii str. Challis substr. CH1

60.45

99.679

0.603
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.323

99.359

0.599
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.486

99.679

0.593
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae D39

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae R6

58.842

99.679

0.587
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

58.842

99.679

0.587
  comGA Lactococcus lactis subsp. cremoris KW2

50.482

99.679

0.503
  comGA Latilactobacillus sakei subsp. sakei 23K

40

92.949

0.372

Multiple sequence alignment