Detailed information NTG1136645

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: DQL59_RS07390
• Genome accession: NZ_LS483326
• Coordinates: 1462409..1462843 (-)
• Length: 144 a.a.
• NCBI ID: WP_002992738.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12045
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1457409..1467843

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL59_RS07365 (NCTC12045_01458)	proC	1458445..1459215 (+)	771	WP_002992745.1	pyrroline-5-carboxylate reductase	-
DQL59_RS07370	-	1459298..1459606 (-)	309	WP_041174321.1	hypothetical protein	-
DQL59_RS07375 (NCTC12045_01459)	-	1459793..1460989 (-)	1197	WP_111681328.1	acetate kinase	-
DQL59_RS07380 (NCTC12045_01460)	comYH	1461048..1462001 (-)	954	WP_111681329.1	class I SAM-dependent methyltransferase	Machinery gene
DQL59_RS07385 (NCTC12045_01461)	comGG	1462099..1462425 (-)	327	WP_010921801.1	competence type IV pilus minor pilin ComGG	-
DQL59_RS07390 (NCTC12045_01462)	comYF	1462409..1462843 (-)	435	WP_002992738.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQL59_RS07395 (NCTC12045_01463)	comGE	1462836..1463120 (-)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
DQL59_RS07400 (NCTC12045_01464)	comGD	1463077..1463505 (-)	429	WP_111681330.1	competence type IV pilus minor pilin ComGD	-
DQL59_RS07405 (NCTC12045_01465)	comYC	1463480..1463806 (-)	327	WP_111681331.1	competence type IV pilus major pilin ComGC	Machinery gene
DQL59_RS07410 (NCTC12045_01466)	comYB	1463808..1464842 (-)	1035	WP_227874808.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQL59_RS07415 (NCTC12045_01467)	comYA	1464778..1465716 (-)	939	WP_002987773.1	competence type IV pilus ATPase ComGA	Machinery gene
DQL59_RS07420 (NCTC12045_01468)	-	1465809..1466174 (-)	366	WP_002986560.1	DUF1033 family protein	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16645.27 Da
• Isoelectric Point: 10.2526

>NTDB_id=1136645 DQL59_RS07390 WP_002992738.1 1462409..1462843(-) (comYF) [Streptococcus pyogenes strain NCTC12045]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1136645 DQL59_RS07390 WP_002992738.1 1462409..1462843(-) (comYF) [Streptococcus pyogenes strain NCTC12045]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	44.776	93.056	0.417
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396