Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DQL59_RS07410 Genome accession   NZ_LS483326
Coordinates   1463808..1464842 (-) Length   344 a.a.
NCBI ID   WP_227874808.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12045     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1458808..1469842
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL59_RS07370 - 1459298..1459606 (-) 309 WP_041174321.1 hypothetical protein -
  DQL59_RS07375 (NCTC12045_01459) - 1459793..1460989 (-) 1197 WP_111681328.1 acetate kinase -
  DQL59_RS07380 (NCTC12045_01460) comYH 1461048..1462001 (-) 954 WP_111681329.1 class I SAM-dependent methyltransferase Machinery gene
  DQL59_RS07385 (NCTC12045_01461) comGG 1462099..1462425 (-) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  DQL59_RS07390 (NCTC12045_01462) comYF 1462409..1462843 (-) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL59_RS07395 (NCTC12045_01463) comGE 1462836..1463120 (-) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  DQL59_RS07400 (NCTC12045_01464) comGD 1463077..1463505 (-) 429 WP_111681330.1 competence type IV pilus minor pilin ComGD -
  DQL59_RS07405 (NCTC12045_01465) comYC 1463480..1463806 (-) 327 WP_111681331.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL59_RS07410 (NCTC12045_01466) comYB 1463808..1464842 (-) 1035 WP_227874808.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL59_RS07415 (NCTC12045_01467) comYA 1464778..1465716 (-) 939 WP_002987773.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL59_RS07420 (NCTC12045_01468) - 1465809..1466174 (-) 366 WP_002986560.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39618.11 Da        Isoelectric Point: 9.7964

>NTDB_id=1136647 DQL59_RS07410 WP_227874808.1 1463808..1464842(-) (comYB) [Streptococcus pyogenes strain NCTC12045]
MISFLRQDISIPSKLSLKKLSSKHQHKFIQLLANLLSTGFSFAEVIAFLKRSQLLQLDYVLKMEESLLKGQGLADMLSGL
GFSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRRKTVEVITYPLILLLFLFVMMLGLRRYLVPQLETQNQITYFLN
HFPAFFIGFCSGLILLFGMVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSYYAREWGTLIGQGLDLMTILDIMAIEKS
SLMKALAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELEIYAQESWEQFFSQLYQVTQLIQPAIFLV
VAVTIVMIYAAILLPIYQNMGGIF

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=1136647 DQL59_RS07410 WP_227874808.1 1463808..1464842(-) (comYB) [Streptococcus pyogenes strain NCTC12045]
TTGATCAGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAGTAAACATCAGCATAA
ATTCATTCAATTACTAGCTAATCTTTTATCTACAGGATTTAGCTTCGCAGAGGTTATTGCTTTTTTAAAAAGAAGCCAGT
TGCTTCAGCTAGATTATGTTCTTAAAATGGAAGAGTCTTTATTAAAAGGACAAGGCTTAGCAGATATGTTGTCGGGTTTA
GGTTTTTCAGATGCTATTCTTACTCAAATTAGTTTAGCTGATAGACACGGTAATATTGAAACAACATTAGTAGCGATTCA
ACATTACTTGAACCAAATGGCAAGGATCAGACGAAAAACTGTTGAAGTTATCACCTATCCTCTTATTCTTTTACTTTTTC
TTTTTGTGATGATGCTAGGGTTGAGACGCTATTTAGTCCCTCAATTAGAAACTCAAAATCAGATAACTTACTTTCTTAAC
CATTTTCCTGCCTTCTTTATAGGTTTTTGCTCAGGTCTTATTTTGTTGTTCGGGATGGTATGGCTACGATGGCGATCTCA
AAGCCGCTTGAAACTCTATAGTCGGCTAAGCCGTTATCCTTTTTTAGGTAAACTGTTAAAACAATACTTAACTAGTTATT
ATGCTAGAGAATGGGGTACGTTAATAGGTCAAGGTCTTGATTTGATGACTATTTTAGACATTATGGCCATTGAGAAATCC
TCACTAATGAAAGCATTAGCTGAGGACATCAGAATGAGTCTGCTTGAAGGGCAAGCCTTTCACATTAAAGTAGCTACCTA
CCCTTTTTTTAAAAAAGAATTAAGTTTAATGATTGAATACGGTGAAATCAAATCGAAACTGGGGGCCGAGTTGGAAATCT
ATGCCCAGGAAAGCTGGGAACAATTTTTTAGTCAGCTTTATCAAGTGACACAACTTATTCAACCAGCTATTTTTTTAGTA
GTTGCTGTGACAATCGTCATGATTTATGCGGCAATCCTATTACCAATTTACCAAAATATGGGAGGTATTTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)

Type II secretion system (T2SS), protein F (T2SSF)

(28-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

53.687

98.547

0.529
  comYB Streptococcus mutans UA159

53.687

98.547

0.529
  comYB Streptococcus gordonii str. Challis substr. CH1

50.294

98.837

0.497
  comGB/cglB Streptococcus mitis NCTC 12261

47.321

97.674

0.462
  comGB/cglB Streptococcus mitis SK321

47.447

96.802

0.459
  comGB/cglB Streptococcus pneumoniae Rx1

45.345

96.802

0.439
  comGB/cglB Streptococcus pneumoniae D39

45.345

96.802

0.439
  comGB/cglB Streptococcus pneumoniae R6

45.345

96.802

0.439
  comGB/cglB Streptococcus pneumoniae TIGR4

45.345

96.802

0.439
  comGB Lactococcus lactis subsp. cremoris KW2

42.462

94.477

0.401

Multiple sequence alignment