Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   DQL59_RS07405 Genome accession   NZ_LS483326
Coordinates   1463480..1463806 (-) Length   108 a.a.
NCBI ID   WP_111681331.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12045     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1458480..1468806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL59_RS07370 - 1459298..1459606 (-) 309 WP_041174321.1 hypothetical protein -
  DQL59_RS07375 (NCTC12045_01459) - 1459793..1460989 (-) 1197 WP_111681328.1 acetate kinase -
  DQL59_RS07380 (NCTC12045_01460) comYH 1461048..1462001 (-) 954 WP_111681329.1 class I SAM-dependent methyltransferase Machinery gene
  DQL59_RS07385 (NCTC12045_01461) comGG 1462099..1462425 (-) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  DQL59_RS07390 (NCTC12045_01462) comYF 1462409..1462843 (-) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL59_RS07395 (NCTC12045_01463) comGE 1462836..1463120 (-) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  DQL59_RS07400 (NCTC12045_01464) comGD 1463077..1463505 (-) 429 WP_111681330.1 competence type IV pilus minor pilin ComGD -
  DQL59_RS07405 (NCTC12045_01465) comYC 1463480..1463806 (-) 327 WP_111681331.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL59_RS07410 (NCTC12045_01466) comYB 1463808..1464842 (-) 1035 WP_227874808.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL59_RS07415 (NCTC12045_01467) comYA 1464778..1465716 (-) 939 WP_002987773.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL59_RS07420 (NCTC12045_01468) - 1465809..1466174 (-) 366 WP_002986560.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12357.32 Da        Isoelectric Point: 9.6766

>NTDB_id=1136646 DQL59_RS07405 WP_111681331.1 1463480..1463806(-) (comYC) [Streptococcus pyogenes strain NCTC12045]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKAHLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=1136646 DQL59_RS07405 WP_111681331.1 1463480..1463806(-) (comYC) [Streptococcus pyogenes strain NCTC12045]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGCGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCATCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC Lactococcus lactis subsp. cremoris KW2

56.863

94.444

0.537
  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528
  comGC/cglC Streptococcus pneumoniae TIGR4

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae D39

60.87

85.185

0.519
  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae R6

60.87

85.185

0.519
  comYC Streptococcus mutans UA140

56.25

88.889

0.5
  comYC Streptococcus mutans UA159

56.25

88.889

0.5
  comYC Streptococcus suis isolate S10

59.259

75

0.444

Multiple sequence alignment