Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   DQL35_RS00695 Genome accession   NZ_LS483325
Coordinates   120213..121151 (+) Length   312 a.a.
NCBI ID   WP_111678809.1    Uniprot ID   A0AAX2LHN5
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC7022     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 115213..126151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL35_RS00675 (NCTC7022_00135) - 115373..116419 (+) 1047 WP_049780478.1 acyltransferase family protein -
  DQL35_RS00680 (NCTC7022_00136) - 116480..116845 (+) 366 WP_037580641.1 DUF1033 family protein -
  DQL35_RS00685 (NCTC7022_00137) - 117382..119385 (+) 2004 WP_111677647.1 DUF1430 domain-containing protein -
  DQL35_RS00690 (NCTC7022_00138) - 119387..120031 (+) 645 WP_111677648.1 ATP-binding cassette domain-containing protein -
  DQL35_RS00695 (NCTC7022_00139) comGA/cglA 120213..121151 (+) 939 WP_111678809.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL35_RS00700 (NCTC7022_00140) comYB 121084..122118 (+) 1035 WP_228294477.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL35_RS00705 (NCTC7022_00141) comGC/cglC 122119..122442 (+) 324 WP_111677650.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL35_RS00710 (NCTC7022_00142) comGD 122420..122845 (+) 426 WP_012514783.1 competence type IV pilus minor pilin ComGD -
  DQL35_RS00715 comGE 122802..123092 (+) 291 WP_043030351.1 competence type IV pilus minor pilin ComGE -
  DQL35_RS00720 (NCTC7022_00143) comYF 123079..123513 (+) 435 WP_111677651.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL35_RS00725 (NCTC7022_00144) comGG 123491..123853 (+) 363 WP_111677652.1 competence type IV pilus minor pilin ComGG -
  DQL35_RS00730 (NCTC7022_00146) - 123920..125262 (+) 1343 WP_172452916.1 IS3 family transposase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35355.55 Da        Isoelectric Point: 7.1483

>NTDB_id=1136550 DQL35_RS00695 WP_111678809.1 120213..121151(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
MVQELAKRLIRQAEELQAQDIYILPRGASYELLMRIGDDRRLIDVCESDRMANLISHFKFVAGMNVGEKRRYQLGACDYD
LDGAKVSLRLSAVGDYQGQESLVIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAMVFSTVHAKSISGVY
ARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQKEFEHHQANRWNQQIDQLLAEGHLNSRQARLEKIIQ

Nucleotide


Download         Length: 939 bp        

>NTDB_id=1136550 DQL35_RS00695 WP_111678809.1 120213..121151(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
ATGGTTCAAGAATTAGCCAAGAGGCTTATCAGGCAGGCCGAAGAATTGCAGGCTCAGGATATTTATATACTGCCAAGAGG
GGCAAGCTATGAGCTTTTGATGAGGATAGGTGATGACAGGAGGCTAATAGATGTTTGTGAAAGTGATCGGATGGCTAATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGAATGTGGGAGAAAAAAGACGCTACCAGCTCGGTGCTTGTGACTACGAC
CTTGATGGCGCTAAGGTATCTCTACGATTATCAGCTGTGGGTGACTATCAGGGACAGGAGAGCTTGGTTATTCGTCTCTT
GTATCATCATCAACGCCAGCTCAGGTATTGGTTTGATGGTTTAGAGCGAGTCACATCAGCTATTGGAGCCAGAGGCCTTT
ACCTCTTTTCTGGACCGGTTGGATCAGGTAAGACAACCCTGATGTATCAGCTAGTCTCTGACTATTGCAAGGAGCTTCAG
GTGATCAGTATTGAGGATCCTGTGGAAATTAAAAATGATCAGCTCCTGCAATTACAGGTTAACGACAGCATTGGCATGAC
ATACGATAATCTGATTAAGCTTTCCTTGCGTCATCGTCCAGATGTGTTGATTATCGGAGAAATTAGAGATACACAGACTG
CTAGAGCGGTTATTAGGGCTAGCCTAACAGGAGCAATGGTCTTTTCAACCGTCCATGCAAAGAGTATTTCAGGCGTTTAC
GCTAGGCTGCTAGAATTAGGCATTTCTAGGGCAGAATTGGATAATAGTCTAGCAATGGTTGCTTACCAGCGATTTATTAG
TGGAGGTGCTTTAATTGATTGTGCGCAAAAGGAATTTGAACATCATCAAGCCAACCGGTGGAATCAGCAGATTGATCAGC
TTCTTGCAGAGGGACATCTCAATAGCAGGCAGGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-264)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.71

99.359

0.683
  comYA Streptococcus mutans UA159

63.987

99.679

0.638
  comYA Streptococcus mutans UA140

63.987

99.679

0.638
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

61.935

99.359

0.615
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.613

99.359

0.612
  comYA Streptococcus gordonii str. Challis substr. CH1

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.613

99.359

0.612
  comGA Lactococcus lactis subsp. cremoris KW2

53.055

99.679

0.529
  comGA Latilactobacillus sakei subsp. sakei 23K

40.493

91.026

0.369

Multiple sequence alignment