Detailed information    

insolico Bioinformatically predicted

Overview


Name   ssbA   Type   Machinery gene
Locus tag   DQM39_RS04800 Genome accession   NZ_LS483298
Coordinates   897700..898119 (+) Length   139 a.a.
NCBI ID   WP_021340323.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8225     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 885190..936675 897700..898119 within 0


Gene organization within MGE regions


Location: 885190..936675
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM39_RS04690 (NCTC8225_00938) - 885190..885810 (-) 621 WP_002989605.1 DUF3862 domain-containing protein -
  DQM39_RS04695 (NCTC8225_00939) - 886173..887261 (-) 1089 WP_002984265.1 site-specific integrase -
  DQM39_RS04700 (NCTC8225_00940) - 887511..888320 (-) 810 WP_002984270.1 type II toxin-antitoxin system PemK/MazF family toxin -
  DQM39_RS04705 (NCTC8225_00941) - 888333..889070 (-) 738 WP_002984272.1 XRE family transcriptional regulator -
  DQM39_RS09960 (NCTC8225_00942) - 889230..889376 (+) 147 WP_021340823.1 hypothetical protein -
  DQM39_RS04710 (NCTC8225_00943) - 889373..889855 (-) 483 WP_023605145.1 hypothetical protein -
  DQM39_RS04715 (NCTC8225_00944) - 889929..890156 (+) 228 WP_002984281.1 hypothetical protein -
  DQM39_RS04720 (NCTC8225_00945) - 890264..890773 (-) 510 WP_011017884.1 hypothetical protein -
  DQM39_RS04730 (NCTC8225_00947) - 891032..891241 (-) 210 WP_002984292.1 hypothetical protein -
  DQM39_RS10235 (NCTC8225_00948) - 891297..891428 (+) 132 WP_002984298.1 hypothetical protein -
  DQM39_RS04735 (NCTC8225_00949) - 891414..891632 (-) 219 WP_032467270.1 hypothetical protein -
  DQM39_RS04740 - 891775..891960 (+) 186 WP_032461902.1 helix-turn-helix domain-containing protein -
  DQM39_RS04745 (NCTC8225_00950) - 892039..892350 (+) 312 WP_014411880.1 hypothetical protein -
  DQM39_RS10240 (NCTC8225_00951) - 892352..892486 (+) 135 WP_012560975.1 hypothetical protein -
  DQM39_RS04750 (NCTC8225_00952) - 892617..892796 (+) 180 WP_012560974.1 hypothetical protein -
  DQM39_RS04755 (NCTC8225_00953) - 892969..893241 (+) 273 WP_000370473.1 hypothetical protein -
  DQM39_RS04760 (NCTC8225_00954) - 893231..893611 (-) 381 WP_000568478.1 hypothetical protein -
  DQM39_RS04765 (NCTC8225_00955) - 893667..894110 (+) 444 WP_012560973.1 hypothetical protein -
  DQM39_RS04770 (NCTC8225_00956) - 894226..895029 (+) 804 WP_021340639.1 DnaD domain protein -
  DQM39_RS04775 (NCTC8225_00957) - 895016..895798 (+) 783 WP_021341158.1 ATP-binding protein -
  DQM39_RS09965 (NCTC8225_00958) - 895789..895926 (+) 138 WP_011018145.1 hypothetical protein -
  DQM39_RS04780 (NCTC8225_00959) - 895937..896293 (+) 357 WP_021341157.1 HTH domain-containing protein -
  DQM39_RS04785 (NCTC8225_00960) - 896274..896528 (+) 255 WP_011018143.1 hypothetical protein -
  DQM39_RS04790 (NCTC8225_00961) - 896550..897032 (+) 483 WP_111680846.1 siphovirus Gp157 family protein -
  DQM39_RS04795 (NCTC8225_00962) - 897033..897707 (+) 675 WP_111680847.1 ERF family protein -
  DQM39_RS04800 (NCTC8225_00963) ssbA 897700..898119 (+) 420 WP_021340323.1 single-stranded DNA-binding protein Machinery gene
  DQM39_RS04805 - 898125..898328 (+) 204 WP_011106686.1 hypothetical protein -
  DQM39_RS04810 (NCTC8225_00964) - 898328..898768 (+) 441 WP_011285574.1 RusA family crossover junction endodeoxyribonuclease -
  DQM39_RS04815 (NCTC8225_00965) - 898765..899121 (+) 357 WP_111680848.1 hypothetical protein -
  DQM39_RS10275 (NCTC8225_00966) - 899118..899354 (+) 237 WP_047235251.1 hypothetical protein -
  DQM39_RS04825 (NCTC8225_00967) - 899348..899632 (+) 285 WP_020905119.1 DUF3310 domain-containing protein -
  DQM39_RS04830 (NCTC8225_00968) - 899629..899898 (+) 270 WP_047235252.1 hypothetical protein -
  DQM39_RS10120 - 899989..900102 (+) 114 Protein_887 YopX family protein -
  DQM39_RS04840 (NCTC8225_00969) - 900099..900383 (+) 285 WP_011889038.1 hypothetical protein -
  DQM39_RS04845 (NCTC8225_00970) - 900387..900869 (+) 483 WP_011017571.1 class I SAM-dependent methyltransferase -
  DQM39_RS04850 (NCTC8225_00971) - 901060..901461 (+) 402 WP_002987468.1 hypothetical protein -
  DQM39_RS04855 (NCTC8225_00972) - 901461..902096 (+) 636 WP_002987471.1 N-6 DNA methylase -
  DQM39_RS04860 (NCTC8225_00973) - 902365..902802 (+) 438 WP_003052405.1 DUF1492 domain-containing protein -
  DQM39_RS04865 (NCTC8225_00974) - 903011..904180 (+) 1170 WP_172450334.1 IS256 family transposase -
  DQM39_RS04870 (NCTC8225_00976) - 905207..906121 (+) 915 WP_011284864.1 hypothetical protein -
  DQM39_RS09970 - 906211..906444 (-) 234 WP_002995461.1 hypothetical protein -
  DQM39_RS04880 (NCTC8225_00978) - 906740..907117 (-) 378 WP_002987543.1 type II toxin-antitoxin system HicB family antitoxin -
  DQM39_RS04885 (NCTC8225_00979) - 907169..907354 (-) 186 WP_001132273.1 type II toxin-antitoxin system HicA family toxin -
  DQM39_RS04890 (NCTC8225_00980) - 907453..907884 (+) 432 WP_020833531.1 terminase small subunit -
  DQM39_RS04895 (NCTC8225_00981) - 907862..909169 (+) 1308 WP_047235253.1 PBSX family phage terminase large subunit -
  DQM39_RS04900 (NCTC8225_00982) - 909181..909855 (+) 675 Protein_900 phage portal protein -
  DQM39_RS04905 (NCTC8225_00983) - 910043..911212 (-) 1170 WP_172450334.1 IS256 family transposase -
  DQM39_RS04910 (NCTC8225_00984) - 911330..912166 (+) 837 Protein_902 phage portal protein -
  DQM39_RS04915 (NCTC8225_00985) - 912147..913772 (+) 1626 WP_002984371.1 phage head morphogenesis protein -
  DQM39_RS04920 (NCTC8225_00986) - 913763..913942 (+) 180 WP_010922213.1 hypothetical protein -
  DQM39_RS04925 (NCTC8225_00987) - 914002..914271 (+) 270 WP_002984375.1 hypothetical protein -
  DQM39_RS04930 (NCTC8225_00988) - 914343..914546 (+) 204 WP_002984377.1 hypothetical protein -
  DQM39_RS04935 (NCTC8225_00989) - 914661..914909 (+) 249 WP_002984380.1 hypothetical protein -
  DQM39_RS04940 (NCTC8225_00990) - 914911..915654 (+) 744 WP_002984382.1 phage repressor protein/antirepressor Ant -
  DQM39_RS04945 (NCTC8225_00991) - 915766..916299 (+) 534 WP_002984384.1 DUF4355 domain-containing protein -
  DQM39_RS04950 (NCTC8225_00992) - 916309..916689 (+) 381 WP_002984386.1 phage protein -
  DQM39_RS04955 (NCTC8225_00993) - 916689..917765 (+) 1077 WP_002984388.1 major capsid protein -
  DQM39_RS04960 (NCTC8225_00994) - 917775..918017 (+) 243 WP_002984390.1 HeH/LEM domain-containing protein -
  DQM39_RS04965 (NCTC8225_00995) - 918031..918384 (+) 354 WP_002984392.1 phage head-tail connector protein -
  DQM39_RS04970 (NCTC8225_00996) - 918381..918689 (+) 309 WP_002984393.1 hypothetical protein -
  DQM39_RS04975 (NCTC8225_00997) - 918670..919035 (+) 366 WP_002984399.1 HK97-gp10 family putative phage morphogenesis protein -
  DQM39_RS04980 (NCTC8225_00998) - 919032..919421 (+) 390 WP_002984401.1 hypothetical protein -
  DQM39_RS04985 (NCTC8225_00999) - 919476..920078 (+) 603 WP_002984403.1 phage major tail protein, TP901-1 family -
  DQM39_RS04990 (NCTC8225_01000) - 920131..920490 (+) 360 WP_002984405.1 tail assembly chaperone -
  DQM39_RS04995 (NCTC8225_01001) - 920532..920861 (+) 330 WP_002984407.1 hypothetical protein -
  DQM39_RS05000 (NCTC8225_01002) - 920876..924142 (+) 3267 WP_047235256.1 tape measure protein -
  DQM39_RS05005 (NCTC8225_01003) - 924174..924953 (+) 780 WP_002984411.1 distal tail protein Dit -
  DQM39_RS05010 (NCTC8225_01004) - 924950..927001 (+) 2052 WP_111677295.1 phage tail spike protein -
  DQM39_RS05015 (NCTC8225_01005) - 926998..928005 (+) 1008 WP_047235257.1 hyaluronoglucosaminidase -
  DQM39_RS05020 (NCTC8225_01006) - 928018..929928 (+) 1911 WP_002987337.1 gp58-like family protein -
  DQM39_RS05025 (NCTC8225_01007) - 929942..930103 (+) 162 WP_002987333.1 hypothetical protein -
  DQM39_RS05030 (NCTC8225_01008) - 930106..930723 (+) 618 WP_111680849.1 DUF1366 domain-containing protein -
  DQM39_RS05035 (NCTC8225_01009) - 930733..931008 (+) 276 WP_002987582.1 hypothetical protein -
  DQM39_RS05040 (NCTC8225_01010) - 931005..931232 (+) 228 WP_003058873.1 phage holin -
  DQM39_RS05045 (NCTC8225_01012) - 931348..932553 (+) 1206 WP_002984418.1 glucosaminidase domain-containing protein -
  DQM39_RS05050 (NCTC8225_01013) - 932623..933057 (-) 435 WP_011017966.1 hypothetical protein -
  DQM39_RS05055 (NCTC8225_01014) sda3 933328..934128 (-) 801 WP_011285611.1 streptodornase Sda3 -
  DQM39_RS05060 (NCTC8225_01015) prx 934366..934554 (+) 189 WP_002984426.1 hypothetical protein Regulator
  DQM39_RS05070 (NCTC8225_01017) - 935145..935759 (+) 615 WP_002989607.1 TVP38/TMEM64 family protein -
  DQM39_RS05075 (NCTC8225_01018) - 935890..936675 (-) 786 WP_002984433.1 hypothetical protein -

Sequence


Protein


Download         Length: 139 a.a.        Molecular weight: 15611.30 Da        Isoelectric Point: 4.6702

>NTDB_id=1135472 DQM39_RS04800 WP_021340323.1 897700..898119(+) (ssbA) [Streptococcus pyogenes strain NCTC8225]
MINNIVLVGRMTKDAELRYTASQVAVATFTLAVNRRFKEQNGEREADFINCVIWRQSAENLANWAKKGALIGITGRIQTR
NYENQQGQRVYVTEVVAESFQMLESCNQQSGQGNSSQNDNSQPFGNSNPMDISDDDLPF

Nucleotide


Download         Length: 420 bp        

>NTDB_id=1135472 DQM39_RS04800 WP_021340323.1 897700..898119(+) (ssbA) [Streptococcus pyogenes strain NCTC8225]
ATGATTAACAACATTGTGCTAGTTGGTCGCATGACCAAGGACGCAGAGCTTCGCTATACAGCGAGTCAAGTAGCTGTAGC
TACGTTCACACTTGCGGTAAACCGCAGATTTAAAGAGCAAAACGGGGAGAGAGAAGCAGATTTCATTAACTGTGTTATCT
GGCGACAGTCTGCTGAAAATCTGGCAAACTGGGCTAAAAAAGGTGCCTTGATCGGAATTACAGGTCGTATCCAGACACGC
AACTACGAAAACCAACAAGGTCAACGCGTATATGTAACAGAAGTTGTTGCAGAGAGTTTCCAAATGTTGGAAAGTTGCAA
TCAACAATCTGGTCAAGGTAACTCTTCGCAAAACGATAACAGTCAACCGTTTGGCAATTCAAACCCAATGGATATTTCAG
ATGATGATCTGCCGTTTTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Bacillus subtilis subsp. subtilis str. 168

54.857

100

0.691

  ssb Latilactobacillus sakei subsp. sakei 23K

52.941

100

0.647

  ssbB/cilA Streptococcus pneumoniae TIGR4

43.885

100

0.439

  ssbB Streptococcus sobrinus strain NIDR 6715-7

43.885

100

0.439

  ssbB/cilA Streptococcus pneumoniae Rx1

43.165

100

0.432

  ssbB/cilA Streptococcus mitis NCTC 12261

43.165

100

0.432

  ssbB/cilA Streptococcus pneumoniae D39

43.165

100

0.432

  ssbB/cilA Streptococcus pneumoniae R6

43.165

100

0.432

  ssbB/cilA Streptococcus mitis SK321

43.165

100

0.432

  ssbB Bacillus subtilis subsp. subtilis str. 168

55.769

74.82

0.417

  ssbA Streptococcus mutans UA159

41.007

100

0.41

  ssb Vibrio cholerae strain A1552

30.636

100

0.381


Multiple sequence alignment