Detailed information    

insolico Bioinformatically predicted

Overview


Name   ssbA   Type   Machinery gene
Locus tag   FGK91_RS06660 Genome accession   NZ_LR590483
Coordinates   1297723..1298148 (-) Length   141 a.a.
NCBI ID   WP_146710361.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8318     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1269681..1306158 1297723..1298148 within 0


Gene organization within MGE regions


Location: 1269681..1306158
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK91_RS06460 (NCTC8318_01290) prx 1269681..1269863 (-) 183 WP_111703187.1 Paratox Regulator
  FGK91_RS06465 (NCTC8318_01291) speA 1270084..1270839 (+) 756 WP_009880239.1 streptococcal pyrogenic exotoxin SpeA -
  FGK91_RS06470 (NCTC8318_01292) - 1270961..1271620 (-) 660 WP_009880240.1 hypothetical protein -
  FGK91_RS06475 (NCTC8318_01293) - 1271620..1271841 (-) 222 WP_009880241.1 hypothetical protein -
  FGK91_RS06480 (NCTC8318_01294) - 1271851..1272624 (-) 774 WP_011054795.1 hypothetical protein -
  FGK91_RS06485 (NCTC8318_01295) - 1272635..1273237 (-) 603 WP_011054796.1 hypothetical protein -
  FGK91_RS06490 (NCTC8318_01296) - 1273249..1274013 (-) 765 WP_011054797.1 CHAP domain-containing protein -
  FGK91_RS06495 (NCTC8318_01297) - 1274015..1274347 (-) 333 WP_011054798.1 phage holin -
  FGK91_RS06500 (NCTC8318_01298) - 1274347..1274670 (-) 324 WP_015055952.1 hypothetical protein -
  FGK91_RS09525 (NCTC8318_01299) - 1274684..1274806 (-) 123 WP_015055953.1 hypothetical protein -
  FGK91_RS06505 (NCTC8318_01300) - 1274820..1275167 (-) 348 WP_009880247.1 DUF1366 domain-containing protein -
  FGK91_RS06510 (NCTC8318_01301) - 1275178..1277040 (-) 1863 WP_009880248.1 DUF859 family phage minor structural protein -
  FGK91_RS06515 (NCTC8318_01302) - 1277045..1280485 (-) 3441 WP_011054801.1 glucosaminidase domain-containing protein -
  FGK91_RS06520 (NCTC8318_01303) - 1280486..1281970 (-) 1485 WP_009880250.1 distal tail protein Dit -
  FGK91_RS06525 (NCTC8318_01304) - 1281971..1283776 (-) 1806 WP_011054802.1 tail protein -
  FGK91_RS06530 (NCTC8318_01305) - 1283769..1284227 (-) 459 WP_009880253.1 hypothetical protein -
  FGK91_RS06535 (NCTC8318_01306) - 1284200..1284517 (-) 318 WP_009880254.1 hypothetical protein -
  FGK91_RS06540 (NCTC8318_01307) - 1284530..1285036 (-) 507 WP_009880255.1 phage major tail protein, TP901-1 family -
  FGK91_RS06545 (NCTC8318_01308) - 1285048..1285458 (-) 411 WP_009880256.1 DUF5072 family protein -
  FGK91_RS06550 (NCTC8318_01309) - 1285460..1285855 (-) 396 WP_009880257.1 hypothetical protein -
  FGK91_RS06555 (NCTC8318_01310) - 1285852..1286163 (-) 312 WP_009880258.1 hypothetical protein -
  FGK91_RS06560 (NCTC8318_01311) - 1286160..1286504 (-) 345 WP_009880259.1 hypothetical protein -
  FGK91_RS06565 (NCTC8318_01312) - 1286518..1286811 (-) 294 WP_009880260.1 HeH/LEM domain-containing protein -
  FGK91_RS06570 (NCTC8318_01313) - 1286823..1287713 (-) 891 WP_009880261.1 hypothetical protein -
  FGK91_RS06575 (NCTC8318_01314) - 1287731..1288300 (-) 570 WP_146710355.1 DUF4355 domain-containing protein -
  FGK91_RS06580 (NCTC8318_01315) - 1288450..1288716 (-) 267 WP_011054805.1 hypothetical protein -
  FGK91_RS06585 (NCTC8318_01316) - 1288723..1289631 (-) 909 WP_009880264.1 minor capsid protein -
  FGK91_RS06590 (NCTC8318_01317) - 1289600..1290925 (-) 1326 WP_009880265.1 phage portal protein -
  FGK91_RS06595 (NCTC8318_01318) - 1290925..1292199 (-) 1275 WP_009880266.1 PBSX family phage terminase large subunit -
  FGK91_RS06600 (NCTC8318_01319) - 1292189..1292569 (-) 381 WP_011285571.1 hypothetical protein -
  FGK91_RS06605 (NCTC8318_01320) - 1292913..1293353 (-) 441 WP_011017866.1 ArpU family phage packaging/lysis transcriptional regulator -
  FGK91_RS06610 (NCTC8318_01321) - 1293626..1294261 (-) 636 WP_021340848.1 N-6 DNA methylase -
  FGK91_RS06615 (NCTC8318_01322) - 1294261..1294662 (-) 402 WP_002987468.1 hypothetical protein -
  FGK91_RS06620 (NCTC8318_01323) - 1294760..1294987 (-) 228 WP_146710356.1 hypothetical protein -
  FGK91_RS06625 (NCTC8318_01324) - 1295000..1295674 (-) 675 WP_003057298.1 DNA methyltransferase -
  FGK91_RS06630 (NCTC8318_01325) - 1295671..1295955 (-) 285 WP_136105806.1 hypothetical protein -
  FGK91_RS06635 (NCTC8318_01326) - 1295952..1296386 (-) 435 WP_146710357.1 YopX family protein -
  FGK91_RS06640 (NCTC8318_01327) - 1296370..1296657 (-) 288 WP_146710378.1 nucleotide modification associated domain-containing protein -
  FGK91_RS06645 (NCTC8318_01328) - 1296711..1297067 (-) 357 WP_146710358.1 hypothetical protein -
  FGK91_RS06650 (NCTC8318_01329) - 1297064..1297504 (-) 441 WP_146710359.1 RusA family crossover junction endodeoxyribonuclease -
  FGK91_RS06655 (NCTC8318_01330) - 1297504..1297710 (-) 207 WP_146710360.1 hypothetical protein -
  FGK91_RS06660 (NCTC8318_01331) ssbA 1297723..1298148 (-) 426 WP_146710361.1 single-stranded DNA-binding protein Machinery gene
  FGK91_RS06665 (NCTC8318_01332) - 1298141..1298815 (-) 675 WP_146710362.1 ERF family protein -
  FGK91_RS06670 (NCTC8318_01333) - 1298816..1299298 (-) 483 WP_146710363.1 siphovirus Gp157 family protein -
  FGK91_RS06675 (NCTC8318_01334) - 1299320..1299574 (-) 255 WP_146710364.1 hypothetical protein -
  FGK91_RS06680 (NCTC8318_01335) - 1299567..1299911 (-) 345 WP_146710365.1 HTH domain-containing protein -
  FGK91_RS09315 (NCTC8318_01336) - 1299922..1300059 (-) 138 WP_011018145.1 hypothetical protein -
  FGK91_RS06685 (NCTC8318_01337) - 1300059..1300901 (-) 843 WP_063629027.1 ATP-binding protein -
  FGK91_RS06690 (NCTC8318_01338) - 1300911..1301813 (-) 903 WP_085613680.1 phage replisome organizer N-terminal domain-containing protein -
  FGK91_RS06695 (NCTC8318_01339) - 1301827..1302144 (-) 318 WP_111703179.1 helix-turn-helix transcriptional regulator -
  FGK91_RS09530 (NCTC8318_01340) - 1302160..1302294 (-) 135 WP_011528543.1 hypothetical protein -
  FGK91_RS06700 (NCTC8318_01341) - 1302325..1302576 (-) 252 WP_011528542.1 hypothetical protein -
  FGK91_RS06705 (NCTC8318_01342) - 1302671..1302889 (-) 219 WP_009881062.1 helix-turn-helix transcriptional regulator -
  FGK91_RS06710 (NCTC8318_01343) - 1303078..1303437 (+) 360 WP_011528540.1 helix-turn-helix transcriptional regulator -
  FGK91_RS06715 (NCTC8318_01344) - 1303421..1303798 (+) 378 WP_011054824.1 ImmA/IrrE family metallo-endopeptidase -
  FGK91_RS09320 (NCTC8318_01345) - 1303809..1303961 (+) 153 WP_011054825.1 hypothetical protein -
  FGK91_RS06720 (NCTC8318_01346) - 1304132..1304818 (+) 687 WP_043885029.1 hypothetical protein -
  FGK91_RS06725 (NCTC8318_01347) - 1304992..1306158 (+) 1167 WP_009880742.1 site-specific integrase -

Sequence


Protein


Download         Length: 141 a.a.        Molecular weight: 15864.56 Da        Isoelectric Point: 5.1848

>NTDB_id=1127056 FGK91_RS06660 WP_146710361.1 1297723..1298148(-) (ssbA) [Streptococcus pyogenes strain NCTC8318]
MINNVVLVGRMTKDAELRYTASQVAVATFTLAVNRRFKEQNGEREADFINCVIWRQSAENLANWAKKGALIGVTGRIQTR
NYENQQGQRVYVTEVVAESFQMLESRNSQQQSGQGNSSQNDNSQSFGNSSPMDISDDMFPF

Nucleotide


Download         Length: 426 bp        

>NTDB_id=1127056 FGK91_RS06660 WP_146710361.1 1297723..1298148(-) (ssbA) [Streptococcus pyogenes strain NCTC8318]
ATGATTAACAACGTTGTACTAGTTGGTCGCATGACCAAGGACGCAGAGCTTCGCTATACAGCGAGTCAAGTAGCTGTAGC
TACGTTCACACTTGCGGTAAACCGCAGATTCAAAGAGCAAAACGGGGAGAGAGAAGCGGATTTCATTAACTGTGTTATCT
GGCGACAGTCTGCTGAAAATTTAGCCAACTGGGCTAAAAAAGGTGCTTTGATCGGAGTTACGGGTCGTATTCAGACACGT
AACTATGAAAACCAACAAGGTCAACGTGTCTATGTGACGGAAGTTGTTGCAGAGAGTTTCCAAATGTTGGAAAGTCGAAA
TAGCCAGCAACAATCTGGTCAAGGGAACTCCTCGCAGAACGATAACAGCCAATCATTTGGTAATAGCTCACCGATGGACA
TTTCAGATGATATGTTTCCTTTCTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Bacillus subtilis subsp. subtilis str. 168

54.286

100

0.674

  ssb Latilactobacillus sakei subsp. sakei 23K

55.882

100

0.674

  ssbB/cilA Streptococcus pneumoniae TIGR4

50.833

85.106

0.433

  ssbB/cilA Streptococcus pneumoniae Rx1

50

85.106

0.426

  ssbB/cilA Streptococcus mitis NCTC 12261

50

85.106

0.426

  ssbB/cilA Streptococcus pneumoniae D39

50

85.106

0.426

  ssbB/cilA Streptococcus pneumoniae R6

50

85.106

0.426

  ssbB/cilA Streptococcus mitis SK321

50

85.106

0.426

  ssbB Bacillus subtilis subsp. subtilis str. 168

53.571

79.433

0.426

  ssbB Streptococcus sobrinus strain NIDR 6715-7

53.774

75.177

0.404

  ssbA Streptococcus mutans UA159

46.281

85.816

0.397

  ssbB Lactococcus lactis subsp. cremoris KW2

48.571

74.468

0.362


Multiple sequence alignment