Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/comX2   Type   Regulator
Locus tag   E0F34_RS09950 Genome accession   NZ_LR536843
Coordinates   1835633..1836112 (-) Length   159 a.a.
NCBI ID   WP_000588864.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1830633..1841112
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F34_RS09950 (SAMEA104035599_01897) comX/comX2 1835633..1836112 (-) 480 WP_000588864.1 sigma-70 family RNA polymerase sigma factor Regulator
  E0F34_RS09955 (SAMEA104035599_01898) nusG 1836234..1836770 (-) 537 WP_000376736.1 transcription termination/antitermination protein NusG -
  E0F34_RS09960 (SAMEA104035599_01899) secE 1836825..1837001 (-) 177 WP_001210991.1 preprotein translocase subunit SecE -
  E0F34_RS09965 rpmG 1837011..1837163 (-) 153 WP_001809375.1 50S ribosomal protein L33 -
  E0F34_RS09970 (SAMEA104035599_01900) pbp2a 1837216..1839411 (-) 2196 WP_061650028.1 penicillin-binding protein PBP2A -
  E0F34_RS09975 (SAMEA104035599_01901) - 1839498..1840373 (+) 876 WP_078170547.1 RluA family pseudouridine synthase -

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 19845.46 Da        Isoelectric Point: 7.3797

>NTDB_id=1126583 E0F34_RS09950 WP_000588864.1 1835633..1836112(-) (comX/comX2) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLADDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH

Nucleotide


Download         Length: 480 bp        

>NTDB_id=1126583 E0F34_RS09950 WP_000588864.1 1835633..1836112(-) (comX/comX2) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGCAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGATCAGTCATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCATTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae Rx1

99.371

100

0.994
  comX/comX1 Streptococcus pneumoniae Rx1

99.371

100

0.994
  comX/comX2 Streptococcus pneumoniae D39

99.371

100

0.994
  comX/comX1 Streptococcus pneumoniae D39

99.371

100

0.994
  comX/comX2 Streptococcus pneumoniae R6

99.371

100

0.994
  comX/comX1 Streptococcus pneumoniae R6

99.371

100

0.994
  comX/comX2 Streptococcus pneumoniae TIGR4

98.742

100

0.987
  comX/comX1 Streptococcus pneumoniae TIGR4

98.742

100

0.987
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

91.824

100

0.918
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

91.824

100

0.918
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

89.937

100

0.899
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

89.873

99.371

0.893
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

48.718

98.113

0.478
  comX/sigX Streptococcus mutans UA159

46

94.34

0.434
  comX/sigX Streptococcus suis isolate S10

45.033

94.969

0.428
  comX/sigX Streptococcus suis D9

45.033

94.969

0.428
  comX/sigX Streptococcus suis P1/7

45.033

94.969

0.428
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

39.216

96.226

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

39.216

96.226

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

40

94.34

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

40

94.34

0.377
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

40

94.34

0.377
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

40

94.34

0.377

Multiple sequence alignment