Detailed information    

insolico Bioinformatically predicted

Overview

Name   ssbA   Type   Machinery gene
Locus tag   EL070_RS05490 Genome accession   NZ_LR134284
Coordinates   1045316..1045708 (-) Length   130 a.a.
NCBI ID   WP_011017370.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8232     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1014999..1058691 1045316..1045708 within 0


Gene organization within MGE regions


Location: 1014999..1058691
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL070_RS05300 (NCTC8232_01061) - 1014999..1015730 (-) 732 WP_232013145.1 LPXTG cell wall anchor domain-containing protein -
  EL070_RS05305 (NCTC8232_01062) lepA 1016054..1017886 (-) 1833 WP_010922253.1 translation elongation factor 4 -
  EL070_RS10025 - 1018010..1018416 (-) 407 Protein_967 nucleoside-diphosphate kinase -
  EL070_RS05320 (NCTC8232_01065) prx 1018705..1018887 (-) 183 WP_011017399.1 hypothetical protein Regulator
  EL070_RS05325 (NCTC8232_01066) speA 1019108..1019863 (+) 756 WP_009880239.1 streptococcal pyrogenic exotoxin SpeA -
  EL070_RS05330 (NCTC8232_01067) - 1019985..1021202 (-) 1218 WP_023611377.1 peptidoglycan amidohydrolase family protein -
  EL070_RS05335 (NCTC8232_01069) - 1021321..1021548 (-) 228 WP_003058873.1 phage holin -
  EL070_RS05340 (NCTC8232_01070) - 1021545..1021817 (-) 273 WP_011017397.1 hypothetical protein -
  EL070_RS05345 (NCTC8232_01071) - 1021829..1022461 (-) 633 WP_023611372.1 hypothetical protein -
  EL070_RS05350 (NCTC8232_01072) - 1022464..1022892 (-) 429 WP_002988448.1 DUF1617 family protein -
  EL070_RS05355 (NCTC8232_01073) - 1022904..1024808 (-) 1905 WP_011017395.1 gp58-like family protein -
  EL070_RS05360 (NCTC8232_01074) - 1024818..1025825 (-) 1008 WP_011017394.1 hyaluronoglucosaminidase -
  EL070_RS05365 (NCTC8232_01075) - 1025822..1027873 (-) 2052 WP_038432431.1 phage tail spike protein -
  EL070_RS05370 (NCTC8232_01076) - 1027870..1028640 (-) 771 WP_011017392.1 distal tail protein Dit -
  EL070_RS05375 (NCTC8232_01077) - 1028653..1032753 (-) 4101 WP_023611657.1 phage tail tape measure protein -
  EL070_RS05385 (NCTC8232_01078) gpG 1032979..1033281 (-) 303 WP_011017390.1 phage tail assembly chaperone G -
  EL070_RS05390 (NCTC8232_01079) - 1033374..1033958 (-) 585 WP_011017389.1 major tail protein -
  EL070_RS05395 (NCTC8232_01080) - 1033970..1034350 (-) 381 WP_011017388.1 hypothetical protein -
  EL070_RS05400 (NCTC8232_01081) - 1034343..1034741 (-) 399 WP_011017387.1 HK97 gp10 family phage protein -
  EL070_RS05405 (NCTC8232_01082) - 1034743..1035105 (-) 363 WP_011017386.1 hypothetical protein -
  EL070_RS05410 (NCTC8232_01083) - 1035098..1035406 (-) 309 WP_011017385.1 hypothetical protein -
  EL070_RS10030 (NCTC8232_01084) - 1035406..1035579 (-) 174 WP_011017384.1 hypothetical protein -
  EL070_RS05415 (NCTC8232_01085) - 1035593..1036726 (-) 1134 WP_011017383.1 phage major capsid protein -
  EL070_RS05420 (NCTC8232_01086) - 1036743..1037549 (-) 807 WP_023611660.1 head maturation protease, ClpP-related -
  EL070_RS05425 (NCTC8232_01087) - 1037530..1038717 (-) 1188 WP_011017381.1 phage portal protein -
  EL070_RS05430 (NCTC8232_01088) - 1038870..1039082 (-) 213 WP_136260634.1 hypothetical protein -
  EL070_RS05435 (NCTC8232_01089) - 1039085..1040815 (-) 1731 WP_011017380.1 terminase large subunit domain-containing protein -
  EL070_RS05440 (NCTC8232_01090) - 1040828..1041145 (-) 318 WP_011017379.1 P27 family phage terminase small subunit -
  EL070_RS05445 (NCTC8232_01091) - 1041286..1041591 (-) 306 WP_011017378.1 HNH endonuclease -
  EL070_RS05450 (NCTC8232_01092) - 1041584..1041970 (-) 387 WP_011017377.1 hypothetical protein -
  EL070_RS05455 (NCTC8232_01093) - 1041996..1042199 (-) 204 WP_011017376.1 hypothetical protein -
  EL070_RS05460 (NCTC8232_01094) - 1042257..1042550 (-) 294 WP_011017375.1 hypothetical protein -
  EL070_RS05465 (NCTC8232_01095) - 1042704..1043279 (-) 576 WP_011054435.1 site-specific integrase -
  EL070_RS05470 (NCTC8232_01096) - 1043439..1043840 (-) 402 WP_011017373.1 hypothetical protein -
  EL070_RS05475 (NCTC8232_01097) - 1043855..1044682 (-) 828 WP_011017372.1 prohibitin family protein -
  EL070_RS05480 (NCTC8232_01098) - 1044685..1045023 (-) 339 WP_011017371.1 helix-turn-helix domain-containing protein -
  EL070_RS05485 (NCTC8232_01099) - 1045020..1045301 (-) 282 WP_011054431.1 hypothetical protein -
  EL070_RS05490 (NCTC8232_01100) ssbA 1045316..1045708 (-) 393 WP_011017370.1 single-stranded DNA-binding protein Machinery gene
  EL070_RS05495 (NCTC8232_01101) - 1045705..1045926 (-) 222 WP_011017369.1 hypothetical protein -
  EL070_RS05500 (NCTC8232_01102) - 1045923..1046408 (-) 486 WP_011017368.1 DUF1642 domain-containing protein -
  EL070_RS05505 (NCTC8232_01103) - 1046413..1047045 (-) 633 WP_023611652.1 N-6 DNA methylase -
  EL070_RS05510 (NCTC8232_01104) - 1047047..1047316 (-) 270 WP_011017366.1 hypothetical protein -
  EL070_RS10035 (NCTC8232_01105) - 1047313..1047483 (-) 171 WP_023611649.1 hypothetical protein -
  EL070_RS05515 (NCTC8232_01106) - 1047480..1047923 (-) 444 WP_011017365.1 YopX family protein -
  EL070_RS10340 (NCTC8232_01107) - 1047940..1048065 (-) 126 WP_257000584.1 hypothetical protein -
  EL070_RS05520 (NCTC8232_01108) - 1048079..1048306 (-) 228 WP_032467212.1 hypothetical protein -
  EL070_RS05525 (NCTC8232_01109) - 1048306..1049118 (-) 813 WP_023611651.1 ATP-binding protein -
  EL070_RS05530 (NCTC8232_01110) - 1049118..1049879 (-) 762 WP_011017361.1 conserved phage C-terminal domain-containing protein -
  EL070_RS05535 (NCTC8232_01111) dnaB 1049872..1051212 (-) 1341 WP_011017360.1 replicative DNA helicase -
  EL070_RS05540 (NCTC8232_01112) - 1051199..1051387 (-) 189 WP_032461348.1 hypothetical protein -
  EL070_RS05545 (NCTC8232_01113) - 1051508..1051699 (-) 192 WP_011017359.1 hypothetical protein -
  EL070_RS05550 (NCTC8232_01114) - 1051792..1052049 (-) 258 WP_011054421.1 hypothetical protein -
  EL070_RS05555 (NCTC8232_01115) - 1052123..1052842 (-) 720 WP_011017357.1 ORF6C domain-containing protein -
  EL070_RS05560 (NCTC8232_01116) - 1052894..1053394 (+) 501 WP_032464978.1 hypothetical protein -
  EL070_RS10345 (NCTC8232_01117) - 1053514..1053648 (-) 135 WP_011017356.1 hypothetical protein -
  EL070_RS05565 (NCTC8232_01118) - 1053722..1053934 (-) 213 WP_011054420.1 helix-turn-helix domain-containing protein -
  EL070_RS05570 (NCTC8232_01119) - 1053969..1054244 (-) 276 WP_011017354.1 hypothetical protein -
  EL070_RS05575 (NCTC8232_01120) - 1054533..1054883 (+) 351 WP_011017353.1 helix-turn-helix domain-containing protein -
  EL070_RS05580 (NCTC8232_01121) - 1054887..1055279 (+) 393 WP_011017352.1 ImmA/IrrE family metallo-endopeptidase -
  EL070_RS05585 (NCTC8232_01122) - 1055290..1056030 (+) 741 WP_011017351.1 type II toxin-antitoxin system PemK/MazF family toxin -
  EL070_RS05590 (NCTC8232_01123) - 1056341..1057537 (+) 1197 WP_011017350.1 tyrosine-type recombinase/integrase -
  EL070_RS05595 (NCTC8232_01128) - 1058059..1058691 (-) 633 WP_014635437.1 TIGR01906 family membrane protein -

Sequence

Protein


Download         Length: 130 a.a.        Molecular weight: 14755.61 Da        Isoelectric Point: 6.3209

>NTDB_id=1120112 EL070_RS05490 WP_011017370.1 1045316..1045708(-) (ssbA) [Streptococcus pyogenes strain NCTC8232]
MINNVVLIGRLTKDVELRYTPSQVACAQFTLAVNRNFKNQDGQKEADFINCVIWRKSAENLSNWAKKGQLIAITGRIQTR
NYENQQGQRVYVTEVVAESFQILEKRDNTANTSSLADSMPDYGPEPDLPF

Nucleotide


Download         Length: 393 bp        

>NTDB_id=1120112 EL070_RS05490 WP_011017370.1 1045316..1045708(-) (ssbA) [Streptococcus pyogenes strain NCTC8232]
ATGATCAATAACGTTGTTTTGATTGGCCGCTTAACAAAAGATGTTGAGCTACGCTATACACCAAGTCAAGTAGCTTGCGC
ACAGTTTACTTTAGCAGTTAATCGTAATTTTAAAAATCAAGATGGGCAAAAAGAGGCTGACTTTATCAATTGTGTCATCT
GGCGAAAGTCTGCCGAGAATTTATCAAACTGGGCTAAAAAAGGGCAATTGATTGCAATAACAGGACGCATACAGACTCGT
AATTATGAAAACCAGCAAGGACAACGTGTCTATGTTACGGAAGTTGTCGCAGAAAGCTTCCAGATTTTGGAGAAGCGTGA
TAACACTGCAAACACAAGCAGTTTAGCTGATAGCATGCCAGACTATGGACCAGAACCAGATTTACCATTTTAG

Domains

Predicted by InterproScan.

Single-strand binding protein family (SSB)

(2-102)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Bacillus subtilis subsp. subtilis str. 168

68.224

82.308

0.562
  ssb Latilactobacillus sakei subsp. sakei 23K

66.972

83.846

0.562
  ssbB Streptococcus sobrinus strain NIDR 6715-7

48.148

100

0.5
  ssbB/cilA Streptococcus pneumoniae TIGR4

44.853

100

0.469
  ssbB/cilA Streptococcus mitis NCTC 12261

44.853

100

0.469
  ssbB/cilA Streptococcus pneumoniae Rx1

44.118

100

0.462
  ssbB/cilA Streptococcus pneumoniae R6

44.118

100

0.462
  ssbB/cilA Streptococcus pneumoniae D39

44.118

100

0.462
  ssbB/cilA Streptococcus mitis SK321

43.704

100

0.454
  ssbA Streptococcus mutans UA159

43.704

100

0.454
  ssbB Bacillus subtilis subsp. subtilis str. 168

53.774

81.538

0.438
  ssbB Lactococcus lactis subsp. cremoris KW2

42.636

99.231

0.423

Multiple sequence alignment