Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   EL081_RS01065 Genome accession   NZ_LR134266
Coordinates   184480..185421 (+) Length   313 a.a.
NCBI ID   WP_126403664.1    Uniprot ID   -
Organism   Streptococcus viridans strain NCTC3166     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 179480..190421
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL081_RS01040 (NCTC3166_00210) - 180435..181223 (+) 789 WP_126403662.1 hypothetical protein -
  EL081_RS01045 (NCTC3166_00211) - 181233..181373 (+) 141 WP_006595142.1 hypothetical protein -
  EL081_RS01050 (NCTC3166_00212) - 181366..182676 (+) 1311 Protein_169 glycosyltransferase family 2 protein -
  EL081_RS01055 (NCTC3166_00214) - 182685..183788 (+) 1104 WP_126403663.1 glycosyl hydrolase family 8 -
  EL081_RS01060 (NCTC3166_00215) - 183996..184373 (+) 378 WP_048717460.1 DUF1033 family protein -
  EL081_RS01065 (NCTC3166_00216) comYA 184480..185421 (+) 942 WP_126403664.1 competence type IV pilus ATPase ComGA Machinery gene
  EL081_RS01070 (NCTC3166_00217) comYB 185363..186385 (+) 1023 WP_126403665.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL081_RS01075 (NCTC3166_00218) comYC 186382..186699 (+) 318 WP_023022076.1 competence type IV pilus major pilin ComGC Machinery gene
  EL081_RS01080 comGD/cglD 186668..187093 (+) 426 WP_042507426.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL081_RS01085 (NCTC3166_00220) comGE 187059..187352 (+) 294 WP_006595134.1 competence type IV pilus minor pilin ComGE -
  EL081_RS01090 (NCTC3166_00221) comGF/cglF 187336..187788 (+) 453 WP_048717662.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL081_RS01095 (NCTC3166_00222) comGG 187754..188200 (+) 447 WP_126403667.1 competence type IV pilus minor pilin ComGG -
  EL081_RS01100 (NCTC3166_00223) comYH 188232..189185 (+) 954 WP_126403668.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35634.71 Da        Isoelectric Point: 5.4602

>NTDB_id=1119542 EL081_RS01065 WP_126403664.1 184480..185421(+) (comYA) [Streptococcus viridans strain NCTC3166]
MVQEIAQSIIRMASNAEAQDIYFVPRASDYQLFLRVGDERRFVETYSQEQMVAVISHFKFMAGMNVGERRRSQLGSCDYS
LGDKVLSLRLSTVGDYRGYESLVIRLLHNEDRELRFWFDQLQELEEKVSKRGLYLFAGPVGSGKTTLMHALAKKKFSGQQ
VMSIEDPVEIKQEEMLQLQLNEAIGMTYDSLIKLSLRHRPDLLLIGEIRDTETARAVIRASLTGVTVFSTIHAKSIPGVY
ERLLELGASEEELRIVLQGICYQRLIKGGGVTDFAIQDYQNHSSQKWNQQMDALYEAGHIELDQAQAEKIIDC

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1119542 EL081_RS01065 WP_126403664.1 184480..185421(+) (comYA) [Streptococcus viridans strain NCTC3166]
ATGGTTCAAGAAATTGCACAATCCATAATTCGAATGGCATCGAATGCCGAAGCTCAGGATATTTATTTTGTTCCTCGAGC
ATCAGACTATCAGCTCTTTCTAAGGGTTGGGGATGAGCGACGCTTTGTCGAGACCTATTCGCAAGAACAAATGGTAGCGG
TCATCAGCCATTTTAAGTTTATGGCAGGGATGAATGTGGGGGAAAGGCGCCGGAGTCAATTGGGCTCCTGTGACTATTCT
CTAGGGGATAAGGTCTTGTCCTTACGCTTGTCTACTGTGGGAGACTATAGGGGATACGAGAGTTTGGTTATTCGCCTGCT
CCATAATGAGGACCGAGAGCTCCGTTTCTGGTTCGACCAACTTCAAGAGCTAGAAGAGAAGGTGAGTAAGCGGGGGCTCT
ACTTATTTGCGGGTCCAGTCGGATCGGGGAAGACGACACTGATGCATGCCCTGGCCAAGAAGAAATTTTCGGGGCAACAA
GTCATGTCGATTGAAGACCCGGTAGAAATTAAGCAAGAAGAGATGCTGCAACTGCAACTCAATGAAGCGATTGGCATGAC
CTATGATAGCTTGATTAAACTGTCTCTGCGTCATCGCCCGGATCTCCTCCTCATCGGAGAAATCCGTGACACGGAGACAG
CTCGCGCAGTTATTCGGGCTAGTCTGACAGGTGTGACAGTCTTTTCCACCATCCATGCCAAGAGCATTCCTGGGGTTTAT
GAACGCCTATTGGAGTTGGGGGCGAGTGAGGAGGAGTTACGGATTGTCCTTCAAGGGATATGTTACCAGCGTTTGATAAA
GGGAGGAGGTGTCACTGACTTTGCCATCCAAGATTACCAAAACCACTCCAGTCAAAAGTGGAACCAGCAAATGGACGCGC
TTTATGAAGCGGGACATATTGAGCTGGATCAGGCGCAAGCCGAAAAAATTATCGATTGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

75.484

99.042

0.748
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

72.581

99.042

0.719
  comGA/cglA/cilD Streptococcus pneumoniae D39

71.935

99.042

0.712
  comGA/cglA/cilD Streptococcus pneumoniae R6

71.935

99.042

0.712
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

71.935

99.042

0.712
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

71.935

99.042

0.712
  comYA Streptococcus mutans UA159

64.856

100

0.649
  comYA Streptococcus mutans UA140

64.856

100

0.649
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.859

99.681

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

55.627

99.361

0.553
  comGA Latilactobacillus sakei subsp. sakei 23K

41.877

88.498

0.371

Multiple sequence alignment