Detailed information NTG1119546

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: EL081_RS01090
• Genome accession: NZ_LR134266
• Coordinates: 187336..187788 (+)
• Length: 150 a.a.
• NCBI ID: WP_048717662.1
• Uniprot ID: -
• Organism: Streptococcus viridans strain NCTC3166
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 182336..192788

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL081_RS01055 (NCTC3166_00214)	-	182685..183788 (+)	1104	WP_126403663.1	glycosyl hydrolase family 8	-
EL081_RS01060 (NCTC3166_00215)	-	183996..184373 (+)	378	WP_048717460.1	DUF1033 family protein	-
EL081_RS01065 (NCTC3166_00216)	comYA	184480..185421 (+)	942	WP_126403664.1	competence type IV pilus ATPase ComGA	Machinery gene
EL081_RS01070 (NCTC3166_00217)	comYB	185363..186385 (+)	1023	WP_126403665.1	competence type IV pilus assembly protein ComGB	Machinery gene
EL081_RS01075 (NCTC3166_00218)	comYC	186382..186699 (+)	318	WP_023022076.1	competence type IV pilus major pilin ComGC	Machinery gene
EL081_RS01080	comGD/cglD	186668..187093 (+)	426	WP_042507426.1	competence type IV pilus minor pilin ComGD	Machinery gene
EL081_RS01085 (NCTC3166_00220)	comGE	187059..187352 (+)	294	WP_006595134.1	competence type IV pilus minor pilin ComGE	-
EL081_RS01090 (NCTC3166_00221)	comGF/cglF	187336..187788 (+)	453	WP_048717662.1	competence type IV pilus minor pilin ComGF	Machinery gene
EL081_RS01095 (NCTC3166_00222)	comGG	187754..188200 (+)	447	WP_126403667.1	competence type IV pilus minor pilin ComGG	-
EL081_RS01100 (NCTC3166_00223)	comYH	188232..189185 (+)	954	WP_126403668.1	class I SAM-dependent methyltransferase	Machinery gene
EL081_RS01105 (NCTC3166_00224)	-	189234..190430 (+)	1197	WP_126403669.1	acetate kinase	-
EL081_RS01110 (NCTC3166_00225)	-	190583..191257 (+)	675	WP_224781595.1	type II CAAX endopeptidase family protein	-
EL081_RS01115 (NCTC3166_00226)	folP	191416..192372 (+)	957	WP_164555425.1	dihydropteroate synthase	-

Sequence

Protein

• Length: 150 a.a.
• Molecular weight: 17203.82 Da
• Isoelectric Point: 4.8970

>NTDB_id=1119546 EL081_RS01090 WP_048717662.1 187336..187788(+) (comGF/cglF) [Streptococcus viridans strain NCTC3166]
MLKRTKLPAFTLLEALVALLVISGGLLVFQGLTSLLRQELQYQSHIKQEEWLLFQDQLDIELSRSQFEEVRDNKLYLVQD
QKPIAIGLAKGGDIRKTDATGRGYQPMIDGVESAWIEKRGDLVSIQLRFEEGLEREVVYRVVEKDKKEAD

Nucleotide

• Length: 453 bp

>NTDB_id=1119546 EL081_RS01090 WP_048717662.1 187336..187788(+) (comGF/cglF) [Streptococcus viridans strain NCTC3166]
CTGTTGAAAAGAACTAAACTGCCAGCCTTTACTTTACTGGAGGCCTTGGTTGCCCTGCTCGTCATTAGCGGTGGTTTATT
GGTGTTTCAAGGATTGACAAGCCTCTTGCGTCAAGAACTCCAGTACCAAAGTCACATCAAGCAAGAGGAATGGCTTCTCT
TTCAGGACCAGCTGGACATTGAATTGTCTCGTAGCCAATTTGAAGAGGTCAGAGACAACAAACTCTATCTTGTTCAGGAT
CAAAAACCCATAGCCATTGGACTGGCTAAGGGAGGAGATATCCGAAAGACAGATGCGACTGGCCGTGGCTATCAACCGAT
GATAGATGGAGTTGAATCAGCCTGGATTGAAAAAAGAGGGGATCTGGTATCTATTCAACTGCGCTTTGAAGAAGGGTTAG
AAAGGGAGGTGGTCTACCGTGTGGTGGAAAAGGATAAAAAAGAAGCAGATTGA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (38-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	56.944	96	0.547
comGF/cglF	Streptococcus pneumoniae D39	56.944	96	0.547
comGF/cglF	Streptococcus pneumoniae R6	56.944	96	0.547
comGF/cglF	Streptococcus pneumoniae TIGR4	56.944	96	0.547
comGF/cglF	Streptococcus mitis NCTC 12261	55.396	92.667	0.513
comGF/cglF	Streptococcus mitis SK321	55.396	92.667	0.513
comYF	Streptococcus mutans UA159	42.069	96.667	0.407
comYF	Streptococcus mutans UA140	42.069	96.667	0.407
comGF	Lactococcus lactis subsp. cremoris KW2	39.286	93.333	0.367