Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   EL020_RS03680 Genome accession   NZ_LR134203
Coordinates   703505..704446 (+) Length   313 a.a.
NCBI ID   WP_020915987.1    Uniprot ID   -
Organism   Streptococcus lutetiensis strain NCTC11436     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 698505..709446
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL020_RS03670 (NCTC11436_00763) rpoC 699270..702908 (+) 3639 WP_020915985.1 DNA-directed RNA polymerase subunit beta' -
  EL020_RS03675 (NCTC11436_00764) - 703065..703433 (+) 369 WP_126402407.1 DUF1033 family protein -
  EL020_RS03680 (NCTC11436_00765) comYA 703505..704446 (+) 942 WP_020915987.1 competence type IV pilus ATPase ComGA Machinery gene
  EL020_RS03685 (NCTC11436_00766) comYB 704370..705413 (+) 1044 WP_231997012.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL020_RS03690 (NCTC11436_00767) comYC 705413..705706 (+) 294 WP_020915989.1 competence type IV pilus major pilin ComGC Machinery gene
  EL020_RS03695 (NCTC11436_00768) comYD 705690..706121 (+) 432 WP_020915990.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL020_RS03700 (NCTC11436_00769) comYE 706075..706368 (+) 294 WP_020915991.1 competence type IV pilus minor pilin ComGE Machinery gene
  EL020_RS03705 (NCTC11436_00770) comYF 706352..706789 (+) 438 WP_043894883.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL020_RS03710 (NCTC11436_00771) comGG 706761..707111 (+) 351 WP_020915993.1 competence type IV pilus minor pilin ComGG -
  EL020_RS03715 (NCTC11436_00772) comYH 707165..708121 (+) 957 WP_020915994.1 class I SAM-dependent methyltransferase Machinery gene
  EL020_RS03720 (NCTC11436_00773) - 708175..709374 (+) 1200 WP_126402408.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35692.88 Da        Isoelectric Point: 5.9480

>NTDB_id=1118951 EL020_RS03680 WP_020915987.1 703505..704446(+) (comYA) [Streptococcus lutetiensis strain NCTC11436]
MIQEKAKQLIKDAVEKNVQDIYIVPKKEHYEIYQRVGDERQFIQEVASDEMTSVISHFKFVAGMNVGEKRRSQLGSCDYE
FAEGEEISLRLSTVGDYRGRESLVIRLLYSGRHDLQYWFDGMKNILEAIDSRGLYLFSGPVGSGKTTLMYQLVREKFPDK
QVITIEDPVEIKQDNMLQLQLNDEIGMTYDNLIKLSLRHRPDILIIGEIRDSETARAVIRASLTGVLVFSTIHAKSIPGV
YARLLELGVSRQELENSLRAIIYQRLIGGGGIVDFAKGDFEHYPPTRWNEQIKSLARDGHIGLEEAKIEKIAL

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1118951 EL020_RS03680 WP_020915987.1 703505..704446(+) (comYA) [Streptococcus lutetiensis strain NCTC11436]
ATGATTCAGGAAAAAGCAAAGCAGCTGATTAAGGATGCTGTTGAAAAGAATGTGCAAGATATTTACATTGTTCCTAAGAA
GGAGCACTATGAAATTTATCAACGTGTTGGAGATGAACGTCAGTTTATCCAAGAAGTTGCTAGTGATGAAATGACAAGCG
TGATTAGTCACTTTAAATTTGTTGCGGGAATGAATGTTGGTGAGAAACGTCGTAGTCAGCTAGGGTCTTGTGATTATGAA
TTTGCTGAGGGTGAAGAGATTTCACTGCGTTTATCCACTGTTGGTGATTATCGCGGGCGTGAGAGCCTGGTCATCAGACT
TCTTTATTCAGGTCGTCATGATTTGCAATATTGGTTCGATGGGATGAAGAATATTTTAGAGGCGATTGATAGTCGAGGCC
TTTATCTTTTTTCCGGGCCGGTAGGGAGTGGAAAGACTACTCTCATGTATCAATTGGTTCGTGAAAAGTTCCCCGATAAG
CAGGTCATTACGATAGAAGACCCTGTTGAGATTAAGCAGGATAATATGTTGCAGCTGCAGCTTAATGATGAAATTGGCAT
GACTTATGATAATCTCATTAAACTCTCGCTTCGCCATAGACCTGATATTTTAATTATTGGAGAGATTCGTGATAGTGAGA
CAGCGCGTGCGGTTATTAGAGCTAGTCTAACAGGTGTGCTCGTCTTTTCAACTATTCATGCGAAAAGTATCCCAGGTGTT
TATGCCAGATTATTGGAGTTGGGAGTTAGTAGACAAGAGCTCGAAAATAGTTTACGAGCGATTATTTATCAACGATTAAT
TGGCGGTGGAGGTATTGTGGATTTTGCCAAAGGAGATTTTGAACACTATCCCCCAACAAGGTGGAATGAGCAAATTAAAA
GCCTTGCTAGGGACGGACATATTGGCCTTGAGGAAGCAAAAATCGAAAAAATTGCCCTTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

71.061

99.361

0.706
  comYA Streptococcus mutans UA140

70.74

99.361

0.703
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

67.097

99.042

0.665
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.064

99.681

0.649
  comYA Streptococcus gordonii str. Challis substr. CH1

64.952

99.361

0.645
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.423

99.681

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.423

99.681

0.642
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.423

99.681

0.642
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.423

99.681

0.642
  comGA Lactococcus lactis subsp. cremoris KW2

53.994

100

0.54
  comGA Latilactobacillus sakei subsp. sakei 23K

43.066

87.54

0.377

Multiple sequence alignment