Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   EL020_RS03685 Genome accession   NZ_LR134203
Coordinates   704370..705413 (+) Length   347 a.a.
NCBI ID   WP_231997012.1    Uniprot ID   -
Organism   Streptococcus lutetiensis strain NCTC11436     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 699370..710413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL020_RS03675 (NCTC11436_00764) - 703065..703433 (+) 369 WP_126402407.1 DUF1033 family protein -
  EL020_RS03680 (NCTC11436_00765) comYA 703505..704446 (+) 942 WP_020915987.1 competence type IV pilus ATPase ComGA Machinery gene
  EL020_RS03685 (NCTC11436_00766) comYB 704370..705413 (+) 1044 WP_231997012.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL020_RS03690 (NCTC11436_00767) comYC 705413..705706 (+) 294 WP_020915989.1 competence type IV pilus major pilin ComGC Machinery gene
  EL020_RS03695 (NCTC11436_00768) comYD 705690..706121 (+) 432 WP_020915990.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL020_RS03700 (NCTC11436_00769) comYE 706075..706368 (+) 294 WP_020915991.1 competence type IV pilus minor pilin ComGE Machinery gene
  EL020_RS03705 (NCTC11436_00770) comYF 706352..706789 (+) 438 WP_043894883.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL020_RS03710 (NCTC11436_00771) comGG 706761..707111 (+) 351 WP_020915993.1 competence type IV pilus minor pilin ComGG -
  EL020_RS03715 (NCTC11436_00772) comYH 707165..708121 (+) 957 WP_020915994.1 class I SAM-dependent methyltransferase Machinery gene
  EL020_RS03720 (NCTC11436_00773) - 708175..709374 (+) 1200 WP_126402408.1 acetate kinase -
  EL020_RS03725 (NCTC11436_00774) - 709534..709731 (+) 198 WP_020915996.1 helix-turn-helix transcriptional regulator -
  EL020_RS03730 (NCTC11436_00775) - 709721..709948 (+) 228 WP_231997018.1 hypothetical protein -
  EL020_RS03735 (NCTC11436_00776) - 709949..710404 (+) 456 WP_231853254.1 ABC transporter permease -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 39526.69 Da        Isoelectric Point: 9.2096

>NTDB_id=1118952 EL020_RS03685 WP_231997012.1 704370..705413(+) (comYB) [Streptococcus lutetiensis strain NCTC11436]
MSKLKALLGTDILALRKQKSKKLPFKKQQKVIQLFNNLFNSGFNLTEIVSFLRRSQLLAEVYVDSMQESLLSGASLADMM
AKLGFSDTIVTQIALADVHGNCQQSLLKIDGYLASMSVVRKKLIEVATYPLILFSFLILIMLGLKNYLLPQLENQNFATQ
IISHFPMIFLGGFALLALGILLGVLYAEHLSPIYLYSQLSRLPIFGRHVRLYLTAYYAREWGNLIGQGIELMEIVELMQR
QKSRLFQEIGKDMQEALLSGQSFHQKVLDYPFFLRELSLMIEYGEVKSKLGRELDIYAEETWQNFFSQLTQATQLIQPSV
FVFVASIIVLIYVAMLLPMYQNMGGNF

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=1118952 EL020_RS03685 WP_231997012.1 704370..705413(+) (comYB) [Streptococcus lutetiensis strain NCTC11436]
ATGAGCAAATTAAAAGCCTTGCTAGGGACGGACATATTGGCCTTGAGGAAGCAAAAATCGAAAAAATTGCCCTTTAAAAA
ACAGCAGAAGGTGATTCAATTATTTAACAATCTCTTTAACAGCGGCTTTAATTTAACAGAAATTGTTTCTTTTTTGAGAC
GAAGTCAGTTGTTGGCGGAAGTTTATGTGGACAGTATGCAAGAGTCATTGTTAAGTGGGGCAAGTTTGGCAGATATGATG
GCTAAGCTGGGCTTTTCAGATACAATTGTCACCCAGATTGCTCTTGCGGATGTTCATGGGAATTGTCAGCAGAGTTTGTT
AAAAATTGATGGTTACTTGGCTAGTATGTCAGTTGTTCGAAAGAAATTGATTGAAGTGGCGACTTATCCTTTGATTTTGT
TTAGCTTTTTAATTCTGATTATGTTGGGCTTGAAAAATTATTTGCTGCCGCAGTTGGAAAATCAAAATTTTGCAACTCAG
ATTATCAGCCATTTTCCTATGATTTTTTTGGGTGGCTTTGCTCTTTTAGCTTTAGGAATTCTGCTTGGGGTTCTGTATGC
CGAGCACTTATCGCCAATTTATCTGTATAGTCAGTTAAGTCGTTTGCCAATATTTGGTCGGCACGTGCGCCTTTATTTGA
CGGCTTATTATGCGCGTGAGTGGGGAAATCTTATCGGACAAGGTATCGAACTGATGGAGATTGTAGAGCTTATGCAGCGG
CAAAAATCACGTCTCTTTCAGGAAATTGGAAAAGATATGCAGGAAGCTTTGTTGTCTGGTCAGTCTTTTCATCAGAAAGT
GCTGGATTACCCTTTCTTTTTGCGTGAACTTAGCTTAATGATTGAATATGGCGAGGTCAAGTCAAAATTAGGTCGTGAGT
TAGATATTTATGCCGAAGAGACTTGGCAGAATTTCTTTAGTCAATTGACGCAGGCAACGCAGCTAATTCAGCCTTCGGTC
TTTGTCTTTGTTGCTTCAATCATCGTTTTAATTTATGTGGCAATGCTTTTGCCGATGTATCAAAATATGGGAGGAAATTT
TTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

64.557

91.066

0.588
  comYB Streptococcus mutans UA159

64.557

91.066

0.588
  comYB Streptococcus gordonii str. Challis substr. CH1

57.647

97.983

0.565
  comGB/cglB Streptococcus mitis NCTC 12261

56.973

97.118

0.553
  comGB/cglB Streptococcus mitis SK321

56.083

97.118

0.545
  comGB/cglB Streptococcus pneumoniae Rx1

55.49

97.118

0.539
  comGB/cglB Streptococcus pneumoniae D39

55.49

97.118

0.539
  comGB/cglB Streptococcus pneumoniae R6

55.49

97.118

0.539
  comGB/cglB Streptococcus pneumoniae TIGR4

55.49

97.118

0.539
  comGB Lactococcus lactis subsp. cremoris KW2

50.893

96.83

0.493

Multiple sequence alignment