Detailed information NTG0111583

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: HAS68_RS00800
• Genome accession: NZ_CP002007
• Coordinates: 125366..125647 (+)
• Length: 93 a.a.
• NCBI ID: WP_009909092.1
• Uniprot ID: A0A116MYU4
• Organism: Streptococcus suis 05HAS68
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 120366..130647

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HAS68_RS00780 (HAS68_0110)	-	122029..122394 (+)	366	WP_002936568.1	DUF1033 family protein	-
HAS68_RS00785 (HAS68_0111)	-	122429..123379 (-)	951	WP_002936565.1	S66 peptidase family protein	-
HAS68_RS00790 (HAS68_0112)	comYA	123465..124415 (+)	951	WP_002936562.1	competence type IV pilus ATPase ComGA	Machinery gene
HAS68_RS00795 (HAS68_0113)	comYB	124327..125364 (+)	1038	WP_255195823.1	competence type IV pilus assembly protein ComGB	Machinery gene
HAS68_RS00800 (HAS68_0114)	comYC	125366..125647 (+)	282	WP_009909092.1	competence type IV pilus major pilin ComGC	Machinery gene
HAS68_RS00805 (HAS68_0115)	comGD	125628..126035 (+)	408	WP_009909093.1	competence type IV pilus minor pilin ComGD	-
HAS68_RS00810 (HAS68_0116)	comYE	126007..126300 (+)	294	WP_009909095.1	competence type IV pilus minor pilin ComGE	Machinery gene
HAS68_RS00815 (HAS68_0117)	comGF/cglF	126287..126721 (+)	435	WP_009909097.1	competence type IV pilus minor pilin ComGF	Machinery gene
HAS68_RS00820 (HAS68_0118)	comGG	126699..127109 (+)	411	WP_009909099.1	competence type IV pilus minor pilin ComGG	-
HAS68_RS00825 (HAS68_0119)	comYH	127166..128119 (+)	954	WP_024409299.1	class I SAM-dependent methyltransferase	Machinery gene
HAS68_RS00830 (HAS68_0120)	-	128169..129356 (+)	1188	WP_013730078.1	acetate kinase	-
HAS68_RS00835 (HAS68_0121)	-	129670..130266 (+)	597	WP_009909104.1	folate family ECF transporter S component	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10320.28 Da
• Isoelectric Point: 8.4284

>NTDB_id=111583 HAS68_RS00800 WP_009909092.1 125366..125647(+) (comYC) [Streptococcus suis 05HAS68]
MKKLVEMKVKGFTLVEMLVVLGIISLLLLLFVPNLSQQKDAIQKKGDAAVVKVVESQMELYELEHDKEATVADLQAAGYI
TEKQAKQYAAAKK

Nucleotide

• Length: 282 bp

>NTDB_id=111583 HAS68_RS00800 WP_009909092.1 125366..125647(+) (comYC) [Streptococcus suis 05HAS68]
ATGAAAAAATTAGTTGAAATGAAGGTAAAAGGGTTCACTCTGGTGGAAATGTTAGTCGTTTTGGGGATCATTAGCCTGCT
CTTGCTCCTTTTTGTGCCAAATTTGAGCCAGCAGAAGGATGCTATTCAGAAGAAGGGGGATGCGGCTGTTGTCAAAGTAG
TGGAGAGCCAGATGGAGCTCTATGAATTGGAACATGACAAGGAAGCAACGGTGGCAGACTTGCAGGCAGCTGGCTACATC
ACTGAAAAACAAGCAAAACAGTATGCTGCGGCGAAAAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A116MYU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	96.774	100	0.968
comGC/cglC	Streptococcus mitis SK321	67.059	91.398	0.613
comGC/cglC	Streptococcus mitis NCTC 12261	67.059	91.398	0.613
comYC	Streptococcus gordonii str. Challis substr. CH1	62.637	97.849	0.613
comGC/cglC	Streptococcus pneumoniae R6	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae D39	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae TIGR4	69.136	87.097	0.602
comGC/cglC	Streptococcus pneumoniae Rx1	69.136	87.097	0.602
comYC	Streptococcus mutans UA140	60.227	94.624	0.57
comYC	Streptococcus mutans UA159	60.227	94.624	0.57
comGC	Lactococcus lactis subsp. cremoris KW2	57.955	94.624	0.548
comGC	Staphylococcus aureus N315	50	83.871	0.419
comGC	Staphylococcus aureus MW2	50	83.871	0.419
comGC	Bacillus subtilis subsp. subtilis str. 168	49.333	80.645	0.398