Detailed information NTG0111585

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: HAS68_RS00815
• Genome accession: NZ_CP002007
• Coordinates: 126287..126721 (+)
• Length: 144 a.a.
• NCBI ID: WP_009909097.1
• Uniprot ID: -
• Organism: Streptococcus suis 05HAS68
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 121287..131721

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HAS68_RS00780 (HAS68_0110)	-	122029..122394 (+)	366	WP_002936568.1	DUF1033 family protein	-
HAS68_RS00785 (HAS68_0111)	-	122429..123379 (-)	951	WP_002936565.1	S66 peptidase family protein	-
HAS68_RS00790 (HAS68_0112)	comYA	123465..124415 (+)	951	WP_002936562.1	competence type IV pilus ATPase ComGA	Machinery gene
HAS68_RS00795 (HAS68_0113)	comYB	124327..125364 (+)	1038	WP_255195823.1	competence type IV pilus assembly protein ComGB	Machinery gene
HAS68_RS00800 (HAS68_0114)	comYC	125366..125647 (+)	282	WP_009909092.1	competence type IV pilus major pilin ComGC	Machinery gene
HAS68_RS00805 (HAS68_0115)	comGD	125628..126035 (+)	408	WP_009909093.1	competence type IV pilus minor pilin ComGD	-
HAS68_RS00810 (HAS68_0116)	comYE	126007..126300 (+)	294	WP_009909095.1	competence type IV pilus minor pilin ComGE	Machinery gene
HAS68_RS00815 (HAS68_0117)	comGF/cglF	126287..126721 (+)	435	WP_009909097.1	competence type IV pilus minor pilin ComGF	Machinery gene
HAS68_RS00820 (HAS68_0118)	comGG	126699..127109 (+)	411	WP_009909099.1	competence type IV pilus minor pilin ComGG	-
HAS68_RS00825 (HAS68_0119)	comYH	127166..128119 (+)	954	WP_024409299.1	class I SAM-dependent methyltransferase	Machinery gene
HAS68_RS00830 (HAS68_0120)	-	128169..129356 (+)	1188	WP_013730078.1	acetate kinase	-
HAS68_RS00835 (HAS68_0121)	-	129670..130266 (+)	597	WP_009909104.1	folate family ECF transporter S component	-
HAS68_RS00840 (HAS68_0122)	-	130277..131533 (+)	1257	WP_013730079.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16449.77 Da
• Isoelectric Point: 5.9234

>NTDB_id=111585 HAS68_RS00815 WP_009909097.1 126287..126721(+) (comGF/cglF) [Streptococcus suis 05HAS68]
MLKSKIPAFTLLECLVALVILSGSLLVFEGLSKLLVQEAHYQGQTVQKEWLVFSSQLRSEWDQAELVKVENGKVYVNKGE
QALAFGKSWSDDFRKTNDRGQGYQPMLYQVDSAAISQENQLVRIDFSFKNGEERTFIYAFKEKS

Nucleotide

• Length: 435 bp

>NTDB_id=111585 HAS68_RS00815 WP_009909097.1 126287..126721(+) (comGF/cglF) [Streptococcus suis 05HAS68]
TTGTTAAAAAGTAAAATTCCTGCTTTTACTCTCTTGGAATGCTTGGTAGCCTTAGTCATCCTTTCAGGTAGTCTTCTGGT
CTTTGAAGGCTTGTCAAAACTGCTGGTCCAAGAAGCGCATTATCAAGGTCAGACCGTTCAAAAGGAATGGTTGGTCTTCT
CTAGCCAATTGCGGTCGGAGTGGGACCAGGCTGAATTGGTCAAGGTTGAAAATGGCAAGGTCTATGTCAACAAAGGTGAA
CAGGCTTTGGCCTTTGGCAAGTCATGGTCGGATGATTTTCGGAAAACAAATGATAGAGGCCAGGGTTACCAACCCATGCT
CTATCAGGTGGATAGCGCAGCCATTTCCCAAGAAAACCAGCTGGTGCGCATCGACTTTAGCTTTAAAAACGGAGAGGAGC
GGACCTTTATCTATGCTTTTAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (37-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	53.191	97.917	0.521
comGF/cglF	Streptococcus pneumoniae D39	53.191	97.917	0.521
comGF/cglF	Streptococcus pneumoniae R6	53.191	97.917	0.521
comGF/cglF	Streptococcus pneumoniae TIGR4	53.191	97.917	0.521
comYF	Streptococcus mutans UA140	50	100	0.5
comGF/cglF	Streptococcus mitis NCTC 12261	53.731	93.056	0.5
comYF	Streptococcus mutans UA159	49.306	100	0.493
comGF/cglF	Streptococcus mitis SK321	50.746	93.056	0.472
comGF	Lactococcus lactis subsp. cremoris KW2	46.809	97.917	0.458