Detailed information NTG1111419

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: ACN076_RS01210
• Genome accession: NZ_CP184836
• Coordinates: 214160..214639 (-)
• Length: 159 a.a.
• NCBI ID: WP_070482535.1
• Uniprot ID: A0A1F0B320
• Organism: Streptococcus sp. K0074
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 209160..219639

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACN076_RS01210 (ACN076_01210)	comX/sigX/comX2/sigX2	214160..214639 (-)	480	WP_070482535.1	sigma-70 family RNA polymerase sigma factor	Regulator
ACN076_RS01215 (ACN076_01215)	ftsH	214760..216718 (-)	1959	WP_420789996.1	ATP-dependent zinc metalloprotease FtsH	-
ACN076_RS01220 (ACN076_01220)	hpt	216734..217276 (-)	543	WP_000892176.1	hypoxanthine phosphoribosyltransferase	-
ACN076_RS01225 (ACN076_01225)	tilS	217281..218558 (-)	1278	WP_001209057.1	tRNA lysidine(34) synthetase TilS	-

Sequence

Protein

• Length: 159 a.a.
• Molecular weight: 19868.53 Da
• Isoelectric Point: 7.4154

>NTDB_id=1111419 ACN076_RS01210 WP_070482535.1 214160..214639(-) (comX/sigX/comX2/sigX2) [Streptococcus sp. K0074]
MLKELYKEVQGIVYKSRNEYYLHLWELSDWDQEGMICLHELISSEEGLVDDIPRLRKYFKTKFRNRILDYLRKQESQKRR
YDKELYEEVGEISHRISEGGLWLDDYYLFHETLRNYRGKQNKEQQEELERVLRDERFRGRQRVLRDLRIVFKEFDIRTH

Nucleotide

• Length: 480 bp

>NTDB_id=1111419 ACN076_RS01210 WP_070482535.1 214160..214639(-) (comX/sigX/comX2/sigX2) [Streptococcus sp. K0074]
ATGCTTAAAGAATTGTATAAAGAAGTCCAGGGAATTGTATATAAGAGTAGAAATGAATATTACCTTCATTTGTGGGAGTT
ATCGGACTGGGATCAAGAGGGAATGATTTGCCTACATGAATTGATTAGTAGCGAAGAAGGGCTAGTAGACGATATTCCTC
GTTTACGTAAATACTTCAAAACAAAATTCCGGAATCGAATTCTAGATTATCTCCGTAAACAAGAAAGTCAAAAACGGAGA
TATGATAAAGAGCTTTATGAAGAAGTGGGTGAGATAAGTCATCGTATAAGTGAGGGAGGACTCTGGCTAGACGATTATTA
TCTCTTTCATGAAACACTAAGAAATTATAGAGGTAAACAAAATAAAGAGCAACAAGAAGAGTTAGAACGCGTCTTAAGAG
ATGAACGCTTCCGAGGGCGTCAAAGAGTGTTAAGAGACTTACGTATTGTGTTTAAAGAGTTTGACATCCGTACTCATTAG

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A1F0B320

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	91.772	99.371	0.912
comX/comX2	Streptococcus pneumoniae D39	90.566	100	0.906
comX/comX1	Streptococcus pneumoniae Rx1	90.566	100	0.906
comX/comX2	Streptococcus pneumoniae R6	90.566	100	0.906
comX/comX1	Streptococcus pneumoniae R6	90.566	100	0.906
comX/comX2	Streptococcus pneumoniae Rx1	90.566	100	0.906
comX/comX1	Streptococcus pneumoniae D39	90.566	100	0.906
comX/comX2	Streptococcus pneumoniae TIGR4	89.937	100	0.899
comX/comX1	Streptococcus pneumoniae TIGR4	89.937	100	0.899
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	90.506	99.371	0.899
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	89.308	100	0.893
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	89.308	100	0.893
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	48.077	98.113	0.472
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	48.077	98.113	0.472
comX/sigX	Streptococcus mutans UA159	45.333	94.34	0.428
comX/sigX	Streptococcus suis D9	43.137	96.226	0.415
comX/sigX	Streptococcus suis isolate S10	43.137	96.226	0.415
comX/sigX	Streptococcus suis P1/7	43.137	96.226	0.415
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	41.611	93.711	0.39
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	41.611	93.711	0.39
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	41.611	93.711	0.39
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	41.611	93.711	0.39
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	40.789	95.597	0.39
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	40.789	95.597	0.39