Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   ACN076_RS00265 Genome accession   NZ_CP184836
Coordinates   40979..41920 (-) Length   313 a.a.
NCBI ID   WP_420789951.1    Uniprot ID   -
Organism   Streptococcus sp. K0074     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 35979..46920
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACN076_RS00225 (ACN076_00225) comYH 36579..37532 (-) 954 WP_420789950.1 class I SAM-dependent methyltransferase Machinery gene
  ACN076_RS00230 (ACN076_00230) - 37593..38180 (-) 588 WP_194250511.1 class I SAM-dependent methyltransferase -
  ACN076_RS00235 (ACN076_00235) comGG/cglG 38213..38626 (-) 414 WP_203176437.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACN076_RS00240 (ACN076_00240) comGF/cglF 38604..39065 (-) 462 WP_061457600.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACN076_RS00245 (ACN076_00245) comGE/cglE 39028..39330 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACN076_RS00250 (ACN076_00250) comGD/cglD 39293..39727 (-) 435 WP_194250512.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACN076_RS00255 (ACN076_00255) comGC/cglC 39690..40013 (-) 324 WP_000738641.1 comG operon protein ComGC Machinery gene
  ACN076_RS00260 (ACN076_00260) comGB/cglB 40015..41058 (-) 1044 WP_153193868.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACN076_RS00265 (ACN076_00265) comGA/cglA/cilD 40979..41920 (-) 942 WP_420789951.1 competence type IV pilus ATPase ComGA Machinery gene
  ACN076_RS00270 (ACN076_00270) - 41997..42362 (-) 366 WP_000286413.1 DUF1033 family protein -
  ACN076_RS00275 (ACN076_00275) - 42513..43571 (-) 1059 WP_153193870.1 zinc-dependent alcohol dehydrogenase family protein -
  ACN076_RS00280 (ACN076_00280) nagA 43733..44884 (-) 1152 WP_153193871.1 N-acetylglucosamine-6-phosphate deacetylase -
  ACN076_RS00285 (ACN076_00285) - 45036..46853 (-) 1818 WP_420789952.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35616.63 Da        Isoelectric Point: 6.1314

>NTDB_id=1111414 ACN076_RS00265 WP_420789951.1 40979..41920(-) (comGA/cglA/cilD) [Streptococcus sp. K0074]
MVQEIAQEIIRSARKKGAQDIYFVPKLDAYEIHMRIGDERCKIGCYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYE
YDQKMASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIGELGKQYRQRGLYLFAGPVGSGKTTLMHELAKFLFKGQQ
VMSIEDPVEIKQDNMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYHRLIGGGGIVDFANKDYQEHQPTSWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1111414 ACN076_RS00265 WP_420789951.1 40979..41920(-) (comGA/cglA/cilD) [Streptococcus sp. K0074]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGGTCGGCTCGGAAAAAAGGGGCGCAGGATATTTATTTTGTCCCTAAGCT
CGACGCCTATGAGATTCATATGAGAATAGGAGACGAGCGTTGTAAAATCGGTTGTTATGACTTTGAAAAATTTGCGGCTG
TCATCAGTCATTTCAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAGAGACGTAGTCAACTTGGTTCCTGTGATTATGAA
TATGACCAGAAGATGGCGTCCCTACGTTTGTCTACTGTAGGCGATTATAGAGGGCATGAGAGTTTAGTCATTCGCTTGTT
GCACGATGAGGAGCAAGATTTACATTTTTGGTTTCAGGATATTGGAGAACTGGGTAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCAGTCGGAAGTGGCAAGACAACCCTGATGCACGAATTGGCCAAGTTCCTCTTTAAAGGACAGCAA
GTCATGTCTATCGAAGATCCTGTCGAAATCAAGCAGGACAACATGCTCCAATTACAGTTGAATGAAGCGATCGGACTTAC
CTATGAAAATCTCATCAAGCTTTCCCTACGGCATCGGCCAGATCTCCTGATTATCGGAGAAATTCGGGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCCAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATTCGAGGTGTTTAT
GAGCGCCTACTGGAGTTGGGTGTGAGTGAGGAGGAATTGGCAGTCGTTCTGCAAGGAGTCTGCTACCATAGATTAATAGG
GGGAGGAGGAATCGTTGACTTTGCAAACAAAGACTACCAAGAACACCAGCCAACTAGTTGGAATGAACAGATTGACCAGC
TTCTTAAAGACGGACATATCACAAGCCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-260)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

97.764

100

0.978
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

94.569

100

0.946
  comGA/cglA/cilD Streptococcus pneumoniae D39

94.569

100

0.946
  comGA/cglA/cilD Streptococcus pneumoniae R6

94.569

100

0.946
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

94.569

100

0.946
  comYA Streptococcus gordonii str. Challis substr. CH1

78.387

99.042

0.776
  comYA Streptococcus mutans UA159

65.595

99.361

0.652
  comYA Streptococcus mutans UA140

65.595

99.361

0.652
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.581

99.042

0.62
  comGA Lactococcus lactis subsp. cremoris KW2

55.449

99.681

0.553
  comGA Latilactobacillus sakei subsp. sakei 23K

41.544

86.901

0.361

Multiple sequence alignment