Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   ACN076_RS00260 Genome accession   NZ_CP184836
Coordinates   40015..41058 (-) Length   347 a.a.
NCBI ID   WP_153193868.1    Uniprot ID   -
Organism   Streptococcus sp. K0074     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 35015..46058
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACN076_RS00220 (ACN076_00220) - 35338..36528 (-) 1191 WP_049521853.1 acetate kinase -
  ACN076_RS00225 (ACN076_00225) comYH 36579..37532 (-) 954 WP_420789950.1 class I SAM-dependent methyltransferase Machinery gene
  ACN076_RS00230 (ACN076_00230) - 37593..38180 (-) 588 WP_194250511.1 class I SAM-dependent methyltransferase -
  ACN076_RS00235 (ACN076_00235) comGG/cglG 38213..38626 (-) 414 WP_203176437.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACN076_RS00240 (ACN076_00240) comGF/cglF 38604..39065 (-) 462 WP_061457600.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACN076_RS00245 (ACN076_00245) comGE/cglE 39028..39330 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACN076_RS00250 (ACN076_00250) comGD/cglD 39293..39727 (-) 435 WP_194250512.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACN076_RS00255 (ACN076_00255) comGC/cglC 39690..40013 (-) 324 WP_000738641.1 comG operon protein ComGC Machinery gene
  ACN076_RS00260 (ACN076_00260) comGB/cglB 40015..41058 (-) 1044 WP_153193868.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACN076_RS00265 (ACN076_00265) comGA/cglA/cilD 40979..41920 (-) 942 WP_420789951.1 competence type IV pilus ATPase ComGA Machinery gene
  ACN076_RS00270 (ACN076_00270) - 41997..42362 (-) 366 WP_000286413.1 DUF1033 family protein -
  ACN076_RS00275 (ACN076_00275) - 42513..43571 (-) 1059 WP_153193870.1 zinc-dependent alcohol dehydrogenase family protein -
  ACN076_RS00280 (ACN076_00280) nagA 43733..44884 (-) 1152 WP_153193871.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 39471.67 Da        Isoelectric Point: 9.9017

>NTDB_id=1111413 ACN076_RS00260 WP_153193868.1 40015..41058(-) (comGB/cglB) [Streptococcus sp. K0074]
MNRLTSFLKTDISQAFRLKRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVTQMRTGLSQGKSFSEMM
ASLGFSSAIVTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRSYLLPQLDSSNIATQ
IIGNLPQIFLGMVGFVSILVLLALTFYKRSSKMRVFSILARIPFLGIFVQTYLTAYYAREWGNMISQGMELTQIFQIMQE
QGSQLFKEIGQDLAQSLQNGREFSQTIATYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLV
FIFVALIIVLLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=1111413 ACN076_RS00260 WP_153193868.1 40015..41058(-) (comGB/cglB) [Streptococcus sp. K0074]
ATGAACAGATTGACCAGCTTCTTAAAGACGGACATATCACAAGCCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAA
GCAAAAAAATATCATCACCCTGTTTAACAATCTCTTTTCCAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATA
GGAGTGCTTTGTTGGACAAGCAGTGCGTGACCCAGATGCGCACGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATG
GCTAGTTTGGGATTTTCAAGTGCCATTGTCACTCAGTTATCCCTAGCGGAAGTCCATGGAAATCTCCACTTGAGTTTGGG
AAAGATAGAAGAATATCTAGACAATCTGGCCAAGGTCAAGAAAAAATTAATTGAAGTAGCGACCTATCCTTTGATTTTAC
TGGGATTTCTTCTCTTAATTATGCTGGGGCTACGTAGCTACCTACTACCACAACTGGATAGTAGTAATATTGCCACCCAA
ATTATCGGAAATCTGCCACAAATCTTTCTAGGAATGGTAGGATTTGTTTCCATACTTGTCCTTTTAGCACTCACTTTTTA
TAAAAGAAGTTCTAAGATGCGCGTCTTTTCTATCTTAGCACGCATTCCTTTTCTTGGAATCTTTGTGCAGACTTATCTGA
CAGCTTATTATGCGCGTGAATGGGGTAATATGATTTCGCAGGGAATGGAGCTGACGCAGATTTTTCAAATCATGCAGGAA
CAAGGTTCCCAGCTCTTTAAAGAAATCGGTCAAGATTTAGCTCAATCCCTACAAAATGGCCGCGAATTTTCTCAAACCAT
AGCAACCTATCCTTTCTTTAAAAAAGAGTTGAGTCTCATCATCGAGTATGGTGAAGTCAAGTCCAAGCTGGGGAGTGAGT
TGGAAATCTATGCTGAAAAAACTTGGGAAGCCTTTTTTACCCGAGTTAACCGCACCATGAATTTGGTGCAGCCACTGGTT
TTTATCTTTGTGGCACTGATTATCGTTTTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTT
TTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus mitis SK321

97.626

97.118

0.948
  comGB/cglB Streptococcus mitis NCTC 12261

96.439

97.118

0.937
  comGB/cglB Streptococcus pneumoniae Rx1

94.659

97.118

0.919
  comGB/cglB Streptococcus pneumoniae D39

94.659

97.118

0.919
  comGB/cglB Streptococcus pneumoniae R6

94.659

97.118

0.919
  comGB/cglB Streptococcus pneumoniae TIGR4

94.659

97.118

0.919
  comYB Streptococcus gordonii str. Challis substr. CH1

72.303

98.847

0.715
  comYB Streptococcus mutans UA140

56.598

98.271

0.556
  comYB Streptococcus mutans UA159

56.598

98.271

0.556
  comGB Lactococcus lactis subsp. cremoris KW2

50.148

97.118

0.487

Multiple sequence alignment