Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   ACN076_RS00245 Genome accession   NZ_CP184836
Coordinates   39028..39330 (-) Length   100 a.a.
NCBI ID   WP_000413380.1    Uniprot ID   -
Organism   Streptococcus sp. K0074     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 34028..44330
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACN076_RS00215 (ACN076_00215) rnpA 34817..35188 (-) 372 WP_000739245.1 ribonuclease P protein component -
  ACN076_RS00220 (ACN076_00220) - 35338..36528 (-) 1191 WP_049521853.1 acetate kinase -
  ACN076_RS00225 (ACN076_00225) comYH 36579..37532 (-) 954 WP_420789950.1 class I SAM-dependent methyltransferase Machinery gene
  ACN076_RS00230 (ACN076_00230) - 37593..38180 (-) 588 WP_194250511.1 class I SAM-dependent methyltransferase -
  ACN076_RS00235 (ACN076_00235) comGG/cglG 38213..38626 (-) 414 WP_203176437.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACN076_RS00240 (ACN076_00240) comGF/cglF 38604..39065 (-) 462 WP_061457600.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACN076_RS00245 (ACN076_00245) comGE/cglE 39028..39330 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACN076_RS00250 (ACN076_00250) comGD/cglD 39293..39727 (-) 435 WP_194250512.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACN076_RS00255 (ACN076_00255) comGC/cglC 39690..40013 (-) 324 WP_000738641.1 comG operon protein ComGC Machinery gene
  ACN076_RS00260 (ACN076_00260) comGB/cglB 40015..41058 (-) 1044 WP_153193868.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACN076_RS00265 (ACN076_00265) comGA/cglA/cilD 40979..41920 (-) 942 WP_420789951.1 competence type IV pilus ATPase ComGA Machinery gene
  ACN076_RS00270 (ACN076_00270) - 41997..42362 (-) 366 WP_000286413.1 DUF1033 family protein -
  ACN076_RS00275 (ACN076_00275) - 42513..43571 (-) 1059 WP_153193870.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11135.11 Da        Isoelectric Point: 9.7273

>NTDB_id=1111410 ACN076_RS00245 WP_000413380.1 39028..39330(-) (comGE/cglE) [Streptococcus sp. K0074]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=1111410 ACN076_RS00245 WP_000413380.1 39028..39330(-) (comGE/cglE) [Streptococcus sp. K0074]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTAATTTTACTAGAAGCAGTAGTTGCTCTAGCTATCTT
TGCCAGCATAGCAACCCTCCTTTTGGGACAAATTCAGAAAAATAGACAAGAAGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGCGTGTAGCTAAGATGGCTCTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTGGAGATTCAGGTGTTTTCT
AGTGAAAAGGGATTGGAGGTTTACCATGGTTCAGAACAGTTGTTGGCTATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

99

100

0.99
  comGE/cglE Streptococcus pneumoniae Rx1

99

100

0.99
  comGE/cglE Streptococcus pneumoniae D39

99

100

0.99
  comGE/cglE Streptococcus pneumoniae R6

99

100

0.99
  comGE/cglE Streptococcus pneumoniae TIGR4

99

100

0.99
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

43.333

90

0.39
  comYE Streptococcus mutans UA159

43.333

90

0.39

Multiple sequence alignment