Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   ACNR93_RS00675 Genome accession   NZ_CP184736
Coordinates   101780..102721 (+) Length   313 a.a.
NCBI ID   WP_420543665.1    Uniprot ID   -
Organism   Streptococcus equinus strain NM-2-29     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 96780..107721
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNR93_RS00665 (ACNR93_00665) rpoC 97538..101176 (+) 3639 WP_420543664.1 DNA-directed RNA polymerase subunit beta' -
  ACNR93_RS00670 (ACNR93_00670) - 101343..101711 (+) 369 WP_021141429.1 DUF1033 family protein -
  ACNR93_RS00675 (ACNR93_00675) comYA 101780..102721 (+) 942 WP_420543665.1 competence type IV pilus ATPase ComGA Machinery gene
  ACNR93_RS00680 (ACNR93_00680) comYB 102645..103688 (+) 1044 WP_420544055.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACNR93_RS00685 (ACNR93_00685) comGC/cglC 103688..103981 (+) 294 WP_033151921.1 competence type IV pilus major pilin ComGC Machinery gene
  ACNR93_RS00690 (ACNR93_00690) comGD 103965..104396 (+) 432 WP_420543666.1 competence type IV pilus minor pilin ComGD -
  ACNR93_RS00695 (ACNR93_00695) comYE 104350..104643 (+) 294 WP_134775786.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACNR93_RS00700 (ACNR93_00700) comYF 104627..105064 (+) 438 WP_003067903.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACNR93_RS00705 (ACNR93_00705) comGG 105051..105386 (+) 336 WP_200769899.1 competence type IV pilus minor pilin ComGG -
  ACNR93_RS00710 (ACNR93_00710) comYH 105440..106396 (+) 957 WP_033151900.1 class I SAM-dependent methyltransferase Machinery gene
  ACNR93_RS00715 (ACNR93_00715) - 106450..107649 (+) 1200 WP_420543667.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35766.88 Da        Isoelectric Point: 5.7732

>NTDB_id=1110920 ACNR93_RS00675 WP_420543665.1 101780..102721(+) (comYA) [Streptococcus equinus strain NM-2-29]
MIQEKAKQLIRDAVEKNAQDIYIIPKAENYEIYQRIGEKRQFIQEVATDEMTSLISHFKFVAGMNVGEKRRSQLGSCDYA
FADDEEISLRLSSVGDYRGRESLVIRLLYSGRHDLQYWFDGMRNILEAIDSRGLYLFSGPVGSGKTTLMYQLVREKFPGK
QVITIEDPVEIKQDNMLQLQLNDEIGMTYDNLIKLSLRHRPDILIIGEIRDSETARAVIRASLTGVLVFSTIHAKSIPGV
YARLLELGVSRQELENSLRTIVYQRLIGGGGVVDFAKRDFEQYPPTRWNEQIDSLARDGHISFEEAKIEKIAL

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1110920 ACNR93_RS00675 WP_420543665.1 101780..102721(+) (comYA) [Streptococcus equinus strain NM-2-29]
ATGATTCAGGAAAAAGCAAAGCAGCTTATTAGAGATGCGGTTGAAAAGAATGCTCAGGATATCTATATTATTCCAAAGGC
AGAAAACTATGAGATTTATCAACGAATTGGTGAGAAGCGCCAGTTTATTCAAGAAGTTGCTACTGATGAAATGACAAGCT
TGATTAGTCACTTTAAATTTGTAGCTGGGATGAATGTTGGTGAAAAGCGTCGTAGTCAGCTTGGTTCTTGTGACTATGCT
TTTGCAGATGATGAGGAGATTTCACTGCGCTTGTCTAGTGTGGGTGATTATCGTGGGCGTGAAAGTCTGGTCATTAGGCT
CCTTTATTCAGGTCGTCATGATTTGCAGTATTGGTTTGATGGAATGAGAAATATTTTAGAGGCCATTGACAGTAGGGGAC
TTTACCTTTTTTCCGGGCCGGTAGGGAGTGGGAAAACCACTCTCATGTATCAATTAGTTCGTGAAAAATTTCCTGGAAAA
CAGGTGATTACGATTGAAGACCCTGTTGAGATAAAACAAGACAATATGTTGCAATTGCAGTTAAATGATGAAATCGGGAT
GACTTATGATAATCTTATCAAGCTCTCGCTTCGTCATAGACCTGATATTTTGATTATTGGTGAGATTCGTGATAGTGAGA
CAGCGCGTGCGGTTATTAGAGCTAGTCTGACAGGAGTCCTTGTTTTTTCAACCATTCATGCGAAAAGTATTCCAGGTGTT
TATGCTAGGTTATTAGAATTGGGTGTTAGTAGGCAGGAACTTGAAAATAGCTTGCGCACTATTGTTTATCAACGATTAAT
TGGTGGTGGAGGTGTAGTTGATTTTGCCAAAAGAGATTTTGAGCAGTATCCCCCAACAAGGTGGAATGAGCAAATTGATA
GCCTTGCTCGAGACGGACATATCAGTTTTGAAGAAGCAAAAATCGAAAAAATTGCCCTTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

71.061

99.361

0.706
  comYA Streptococcus mutans UA140

70.74

99.361

0.703
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.71

99.042

0.681
  comYA Streptococcus gordonii str. Challis substr. CH1

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.103

99.681

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

54.633

100

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

42.701

87.54

0.374

Multiple sequence alignment