Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   ACNR93_RS00680 Genome accession   NZ_CP184736
Coordinates   102645..103688 (+) Length   347 a.a.
NCBI ID   WP_420544055.1    Uniprot ID   -
Organism   Streptococcus equinus strain NM-2-29     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 97645..108688
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNR93_RS00670 (ACNR93_00670) - 101343..101711 (+) 369 WP_021141429.1 DUF1033 family protein -
  ACNR93_RS00675 (ACNR93_00675) comYA 101780..102721 (+) 942 WP_420543665.1 competence type IV pilus ATPase ComGA Machinery gene
  ACNR93_RS00680 (ACNR93_00680) comYB 102645..103688 (+) 1044 WP_420544055.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACNR93_RS00685 (ACNR93_00685) comGC/cglC 103688..103981 (+) 294 WP_033151921.1 competence type IV pilus major pilin ComGC Machinery gene
  ACNR93_RS00690 (ACNR93_00690) comGD 103965..104396 (+) 432 WP_420543666.1 competence type IV pilus minor pilin ComGD -
  ACNR93_RS00695 (ACNR93_00695) comYE 104350..104643 (+) 294 WP_134775786.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACNR93_RS00700 (ACNR93_00700) comYF 104627..105064 (+) 438 WP_003067903.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACNR93_RS00705 (ACNR93_00705) comGG 105051..105386 (+) 336 WP_200769899.1 competence type IV pilus minor pilin ComGG -
  ACNR93_RS00710 (ACNR93_00710) comYH 105440..106396 (+) 957 WP_033151900.1 class I SAM-dependent methyltransferase Machinery gene
  ACNR93_RS00715 (ACNR93_00715) - 106450..107649 (+) 1200 WP_420543667.1 acetate kinase -
  ACNR93_RS00720 (ACNR93_00720) - 107807..108004 (+) 198 WP_021141442.1 helix-turn-helix transcriptional regulator -
  ACNR93_RS00725 (ACNR93_00725) - 108060..108512 (+) 453 WP_074483978.1 ABC transporter permease -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 39718.14 Da        Isoelectric Point: 9.7733

>NTDB_id=1110921 ACNR93_RS00680 WP_420544055.1 102645..103688(+) (comYB) [Streptococcus equinus strain NM-2-29]
MSKLIALLETDISVLKKQKSKKLPFKKQQKVIQLFNNLFNSGFTLTEIVSFLRRSQLLQESYVNSMQESLLSGATLADMM
ARLGFSDTIVTQIALADVHGNCQQSLVKIDRYLASMSVVRKKLIEVATYPLILLSFLILIMLGLKNYLLPQLESQNFATQ
IIAHFPMIFLGSFVLLGLAVVLGFFYARRLSPIYLFSQISRLPIIGRFIRLYLTAYYAREWGNLIGQGIDLMEIVALMQH
QKSRLFQEIGKDMQQALLSGQSFHQKVLDYPFFLRELSLMIEYGEVKSKLGRELDIYAEETWQTFFSQLTQATQLIQPLV
FVFVALIIVLIYVAMLLPMYQNMGGNF

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=1110921 ACNR93_RS00680 WP_420544055.1 102645..103688(+) (comYB) [Streptococcus equinus strain NM-2-29]
ATGAGCAAATTGATAGCCTTGCTCGAGACGGACATATCAGTTTTGAAGAAGCAAAAATCGAAAAAATTGCCCTTTAAAAA
ACAACAGAAGGTCATTCAATTATTTAATAATTTGTTTAACAGTGGCTTTACTTTAACTGAGATAGTGTCTTTTTTGAGAC
GGAGTCAGTTATTGCAGGAATCATATGTGAATAGTATGCAGGAGTCCTTGCTGAGTGGCGCAACTTTAGCAGATATGATG
GCAAGGTTAGGCTTTTCAGATACGATTGTGACTCAGATTGCTTTGGCTGATGTTCATGGAAATTGTCAGCAAAGTCTTGT
AAAAATCGATCGTTATTTAGCTAGCATGTCTGTTGTGCGAAAGAAGCTGATTGAAGTGGCGACTTACCCTTTGATTTTAT
TAAGTTTTTTGATTTTGATAATGCTTGGCTTAAAAAATTATTTATTGCCGCAACTTGAAAGTCAAAATTTTGCTACTCAG
ATTATTGCCCATTTTCCAATGATTTTCTTGGGGAGCTTTGTACTTTTAGGACTAGCAGTTGTTCTAGGATTTTTCTATGC
TAGGCGTTTATCACCAATCTATCTTTTTAGCCAGATTAGTCGCTTGCCGATAATAGGGCGATTCATTCGTCTTTATCTAA
CAGCTTATTATGCGCGTGAGTGGGGAAATCTTATTGGGCAGGGGATTGATTTGATGGAAATTGTAGCATTGATGCAGCAC
CAAAAGTCGCGTCTTTTTCAAGAGATTGGTAAGGATATGCAGCAAGCTCTTTTGTCTGGTCAATCATTTCATCAAAAAGT
TCTAGATTATCCCTTCTTTTTGAGGGAACTGAGCCTGATGATTGAGTACGGAGAAGTTAAGTCAAAACTTGGTCGGGAGC
TTGATATCTATGCTGAGGAAACATGGCAGACTTTCTTCAGCCAATTAACTCAGGCAACACAGCTGATTCAACCGCTAGTT
TTTGTCTTTGTTGCTTTAATTATTGTTTTAATTTATGTGGCAATGCTTTTGCCAATGTATCAAAATATGGGAGGAAATTT
TTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

63.158

98.559

0.622
  comYB Streptococcus mutans UA159

63.158

98.559

0.622
  comYB Streptococcus gordonii str. Challis substr. CH1

58.892

98.847

0.582
  comGB/cglB Streptococcus mitis NCTC 12261

57.864

97.118

0.562
  comGB/cglB Streptococcus mitis SK321

57.27

97.118

0.556
  comGB/cglB Streptococcus pneumoniae Rx1

56.973

97.118

0.553
  comGB/cglB Streptococcus pneumoniae D39

56.973

97.118

0.553
  comGB/cglB Streptococcus pneumoniae R6

56.973

97.118

0.553
  comGB/cglB Streptococcus pneumoniae TIGR4

56.973

97.118

0.553
  comGB Lactococcus lactis subsp. cremoris KW2

50

97.406

0.487

Multiple sequence alignment