Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   ACK2I7_RS00355 Genome accession   NZ_CP176632
Coordinates   72542..72859 (+) Length   105 a.a.
NCBI ID   WP_003028473.1    Uniprot ID   A0A0P0N5S2
Organism   Streptococcus anginosus strain SFAD 40     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 67542..77859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK2I7_RS00325 - 67665..68195 (+) 531 WP_003032280.1 FUSC family protein -
  ACK2I7_RS00330 - 68272..68631 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  ACK2I7_RS00335 glnA 68670..70016 (+) 1347 WP_003027006.1 type I glutamate--ammonia ligase -
  ACK2I7_RS00340 - 70205..70570 (+) 366 WP_003027003.1 DUF1033 family protein -
  ACK2I7_RS00345 comYA 70640..71581 (+) 942 WP_003027001.1 competence type IV pilus ATPase ComGA Machinery gene
  ACK2I7_RS00350 comYB 71523..72545 (+) 1023 WP_041783985.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACK2I7_RS00355 comYC 72542..72859 (+) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  ACK2I7_RS00360 comYD 72819..73247 (+) 429 WP_021001232.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACK2I7_RS00365 comGE/cglE 73219..73512 (+) 294 WP_021001233.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACK2I7_RS00370 comGF/cglF 73496..73933 (+) 438 WP_041783987.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACK2I7_RS00375 comGG 73914..74240 (+) 327 WP_021001234.1 competence type IV pilus minor pilin ComGG -
  ACK2I7_RS00380 comYH 74312..75265 (+) 954 WP_021001235.1 class I SAM-dependent methyltransferase Machinery gene
  ACK2I7_RS00385 - 75312..76511 (+) 1200 WP_021001236.1 acetate kinase -

Sequence

Protein


Download         Length: 105 a.a.        Molecular weight: 11622.72 Da        Isoelectric Point: 10.1006

>NTDB_id=1081680 ACK2I7_RS00355 WP_003028473.1 72542..72859(+) (comYC) [Streptococcus anginosus strain SFAD 40]
MKKLKSLKVKGFTLVEMLVVLLIISVLMLLFVPNLTKQKEAVTEKGNAAVVKVVESQAELFEVNHTNEKATLSKLVNEGT
ITDKQAASYKAYYAKHTKEARSVAD

Nucleotide


Download         Length: 318 bp        

>NTDB_id=1081680 ACK2I7_RS00355 WP_003028473.1 72542..72859(+) (comYC) [Streptococcus anginosus strain SFAD 40]
ATGAAAAAATTAAAAAGTTTGAAGGTTAAAGGTTTTACTTTAGTAGAAATGTTAGTCGTACTTCTTATCATCAGTGTTTT
GATGCTCTTATTTGTACCGAATTTGACCAAGCAAAAAGAAGCTGTAACGGAAAAAGGAAATGCAGCGGTGGTAAAAGTTG
TGGAAAGCCAAGCGGAGCTGTTTGAGGTCAATCACACCAATGAAAAAGCGACACTCTCAAAATTAGTCAACGAAGGCACG
ATTACAGACAAGCAGGCAGCATCTTATAAGGCTTACTATGCGAAACATACAAAAGAAGCTCGTTCTGTTGCAGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(8-30)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0P0N5S2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

73.333

100

0.733
  comYC Streptococcus mutans UA159

66.667

100

0.667
  comYC Streptococcus mutans UA140

66.667

100

0.667
  comGC/cglC Streptococcus mitis NCTC 12261

68.627

97.143

0.667
  comGC/cglC Streptococcus mitis SK321

68.627

97.143

0.667
  comGC/cglC Streptococcus pneumoniae R6

66.667

97.143

0.648
  comGC/cglC Streptococcus pneumoniae D39

66.667

97.143

0.648
  comGC/cglC Streptococcus pneumoniae Rx1

66.667

97.143

0.648
  comGC/cglC Streptococcus pneumoniae TIGR4

66.667

97.143

0.648
  comYC Streptococcus suis isolate S10

66.292

84.762

0.562
  comGC Lactococcus lactis subsp. cremoris KW2

54.808

99.048

0.543

Multiple sequence alignment