Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   ACK2I7_RS00350 Genome accession   NZ_CP176632
Coordinates   71523..72545 (+) Length   340 a.a.
NCBI ID   WP_041783985.1    Uniprot ID   A0AAP6EMB9
Organism   Streptococcus anginosus strain SFAD 40     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 66523..77545
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK2I7_RS00325 - 67665..68195 (+) 531 WP_003032280.1 FUSC family protein -
  ACK2I7_RS00330 - 68272..68631 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  ACK2I7_RS00335 glnA 68670..70016 (+) 1347 WP_003027006.1 type I glutamate--ammonia ligase -
  ACK2I7_RS00340 - 70205..70570 (+) 366 WP_003027003.1 DUF1033 family protein -
  ACK2I7_RS00345 comYA 70640..71581 (+) 942 WP_003027001.1 competence type IV pilus ATPase ComGA Machinery gene
  ACK2I7_RS00350 comYB 71523..72545 (+) 1023 WP_041783985.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACK2I7_RS00355 comYC 72542..72859 (+) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  ACK2I7_RS00360 comYD 72819..73247 (+) 429 WP_021001232.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACK2I7_RS00365 comGE/cglE 73219..73512 (+) 294 WP_021001233.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACK2I7_RS00370 comGF/cglF 73496..73933 (+) 438 WP_041783987.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACK2I7_RS00375 comGG 73914..74240 (+) 327 WP_021001234.1 competence type IV pilus minor pilin ComGG -
  ACK2I7_RS00380 comYH 74312..75265 (+) 954 WP_021001235.1 class I SAM-dependent methyltransferase Machinery gene
  ACK2I7_RS00385 - 75312..76511 (+) 1200 WP_021001236.1 acetate kinase -

Sequence

Protein


Download         Length: 340 a.a.        Molecular weight: 39122.46 Da        Isoelectric Point: 9.6306

>NTDB_id=1081679 ACK2I7_RS00350 WP_041783985.1 71523..72545(+) (comYB) [Streptococcus anginosus strain SFAD 40]
MQQDMSLLSRQKRKKLSIVRQKKVVELLNNLFSSGFHLAEMIDFLKRSALLEKTYVEKMKEGLATGKPFSEIMASLGFSD
SVVTQLSLAELHGNLSLSLTKIEEYLENVSKVKKKLIEVATYPFILLIFLVFIMLGLRNYLLPQLERQNSATQLISQLPQ
IFLGSLVVVLVLLAIGFYWFRKSSKIVVFSFLARLPFCGTFIQTYLTAYYAREWGNMIGQGLELSQIFQMMQGQRSAMFQ
EIGKDLEIALQNGQEFSQVVKYYPFFKKELGLIIEYGEVKSKLGCELEVYAQKTWETFFKRVHQAMNVIQPLVFVFVALM
IVLLYAAMLLPIYQNMEVQL

Nucleotide


Download         Length: 1023 bp        

>NTDB_id=1081679 ACK2I7_RS00350 WP_041783985.1 71523..72545(+) (comYB) [Streptococcus anginosus strain SFAD 40]
ATGCAGCAGGACATGTCACTTTTGAGCAGGCAGAAACGGAAAAAATTATCCATAGTTAGGCAGAAAAAAGTCGTAGAGTT
GCTGAATAATCTTTTTTCTAGCGGCTTTCATTTAGCAGAAATGATTGATTTTTTGAAGCGGAGTGCCCTCCTAGAAAAAA
CCTATGTGGAAAAGATGAAAGAGGGTTTAGCAACAGGAAAACCTTTTTCAGAAATTATGGCTAGTTTAGGATTTTCAGAT
AGTGTTGTCACTCAGCTTTCACTGGCAGAGCTACATGGGAATCTCTCACTCAGCCTGACTAAGATTGAGGAATACTTGGA
AAATGTCTCAAAAGTCAAGAAAAAGTTAATTGAGGTAGCCACTTATCCATTCATTTTACTTATTTTTTTAGTATTCATTA
TGTTAGGGCTGCGCAATTATTTACTTCCGCAGTTAGAACGCCAAAATAGTGCAACGCAGCTGATTAGTCAGTTGCCGCAA
ATTTTTCTGGGTTCACTAGTAGTAGTCCTTGTTTTGTTAGCGATAGGTTTTTATTGGTTTAGAAAAAGCTCAAAAATAGT
AGTGTTTAGCTTCTTGGCTCGACTTCCTTTTTGTGGAACTTTTATTCAAACCTATTTGACAGCTTATTATGCGAGAGAAT
GGGGGAATATGATTGGTCAAGGTTTAGAACTTAGTCAGATTTTTCAAATGATGCAAGGGCAACGCTCTGCTATGTTTCAA
GAAATTGGAAAAGATTTAGAAATTGCGTTGCAAAATGGTCAGGAATTTTCACAAGTAGTGAAATATTATCCGTTTTTTAA
AAAGGAATTGGGCTTGATAATTGAATACGGTGAAGTGAAATCCAAATTGGGGTGTGAATTAGAAGTTTATGCCCAAAAAA
CATGGGAGACATTTTTTAAACGTGTTCATCAAGCGATGAATGTCATTCAACCACTAGTGTTTGTCTTTGTGGCTCTAATG
ATTGTATTGTTGTATGCAGCCATGTTGCTGCCAATTTATCAAAATATGGAGGTTCAATTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(26-143)

Type II secretion system (T2SS), protein F (T2SSF)

(211-331)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

73.529

100

0.735
  comGB/cglB Streptococcus mitis NCTC 12261

69.527

99.412

0.691
  comGB/cglB Streptococcus mitis SK321

67.857

98.824

0.671
  comGB/cglB Streptococcus pneumoniae TIGR4

67.56

98.824

0.668
  comGB/cglB Streptococcus pneumoniae R6

67.56

98.824

0.668
  comGB/cglB Streptococcus pneumoniae Rx1

67.56

98.824

0.668
  comGB/cglB Streptococcus pneumoniae D39

67.56

98.824

0.668
  comYB Streptococcus mutans UA159

60.882

100

0.609
  comYB Streptococcus mutans UA140

60.588

100

0.606
  comGB Lactococcus lactis subsp. cremoris KW2

52.802

99.706

0.526

Multiple sequence alignment