Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGF/cglF   Type   Machinery gene
Locus tag   ACK2I7_RS00370 Genome accession   NZ_CP176632
Coordinates   73496..73933 (+) Length   145 a.a.
NCBI ID   WP_041783987.1    Uniprot ID   A0AAP6EPH2
Organism   Streptococcus anginosus strain SFAD 40     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 68496..78933
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK2I7_RS00335 glnA 68670..70016 (+) 1347 WP_003027006.1 type I glutamate--ammonia ligase -
  ACK2I7_RS00340 - 70205..70570 (+) 366 WP_003027003.1 DUF1033 family protein -
  ACK2I7_RS00345 comYA 70640..71581 (+) 942 WP_003027001.1 competence type IV pilus ATPase ComGA Machinery gene
  ACK2I7_RS00350 comYB 71523..72545 (+) 1023 WP_041783985.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACK2I7_RS00355 comYC 72542..72859 (+) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  ACK2I7_RS00360 comYD 72819..73247 (+) 429 WP_021001232.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACK2I7_RS00365 comGE/cglE 73219..73512 (+) 294 WP_021001233.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACK2I7_RS00370 comGF/cglF 73496..73933 (+) 438 WP_041783987.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACK2I7_RS00375 comGG 73914..74240 (+) 327 WP_021001234.1 competence type IV pilus minor pilin ComGG -
  ACK2I7_RS00380 comYH 74312..75265 (+) 954 WP_021001235.1 class I SAM-dependent methyltransferase Machinery gene
  ACK2I7_RS00385 - 75312..76511 (+) 1200 WP_021001236.1 acetate kinase -
  ACK2I7_RS00390 glmS 76863..78677 (+) 1815 WP_003026983.1 glutamine--fructose-6-phosphate transaminase (isomerizing) -

Sequence

Protein


Download         Length: 145 a.a.        Molecular weight: 16769.29 Da        Isoelectric Point: 10.0941

>NTDB_id=1081683 ACK2I7_RS00370 WP_041783987.1 73496..73933(+) (comGF/cglF) [Streptococcus anginosus strain SFAD 40]
MFKANKVKAFTLLEALIALFVISGSVLLFQSMTRLLASEVQARQHSEQREWLLFADQLEAELARSSFEKVENNRLYMKQD
GKVIAFGKSSGQDFRKTNANGKGYQPMVYDVKKAEISQKNELIHVRLTFRRGLEREFVYRVETES

Nucleotide


Download         Length: 438 bp        

>NTDB_id=1081683 ACK2I7_RS00370 WP_041783987.1 73496..73933(+) (comGF/cglF) [Streptococcus anginosus strain SFAD 40]
GTGTTCAAGGCAAATAAAGTGAAAGCTTTTACCCTTTTAGAGGCTCTGATTGCCCTCTTTGTCATTAGTGGAAGTGTGTT
GCTGTTTCAATCTATGACGCGCCTTCTAGCTTCTGAAGTCCAAGCTCGTCAACACAGTGAACAACGAGAATGGCTTTTGT
TTGCAGATCAACTAGAAGCAGAGTTGGCTCGTTCTTCATTTGAAAAGGTGGAGAATAATCGTTTATATATGAAACAGGAC
GGCAAGGTGATTGCATTTGGAAAGTCAAGTGGACAGGATTTCAGAAAAACCAATGCGAATGGGAAAGGTTACCAGCCGAT
GGTTTATGATGTAAAAAAAGCAGAAATCTCACAGAAAAATGAGCTGATTCATGTTAGACTGACGTTTAGGCGAGGATTGG
AAAGGGAGTTTGTCTATCGTGTGGAAACAGAAAGTTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(38-134)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGF/cglF Streptococcus pneumoniae R6

66.901

97.931

0.655
  comGF/cglF Streptococcus pneumoniae TIGR4

66.901

97.931

0.655
  comGF/cglF Streptococcus pneumoniae Rx1

66.901

97.931

0.655
  comGF/cglF Streptococcus pneumoniae D39

66.901

97.931

0.655
  comGF/cglF Streptococcus mitis NCTC 12261

67.143

96.552

0.648
  comGF/cglF Streptococcus mitis SK321

67.143

96.552

0.648
  comYF Streptococcus mutans UA159

45.185

93.103

0.421
  comYF Streptococcus mutans UA140

45.185

93.103

0.421
  comGF Lactococcus lactis subsp. cremoris KW2

42.222

93.103

0.393

Multiple sequence alignment