Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   ACK2I7_RS00345 Genome accession   NZ_CP176632
Coordinates   70640..71581 (+) Length   313 a.a.
NCBI ID   WP_003027001.1    Uniprot ID   A0AAP6BQB5
Organism   Streptococcus anginosus strain SFAD 40     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 65640..76581
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK2I7_RS00320 - 65951..67150 (+) 1200 WP_057489559.1 phosphoglycerate kinase -
  ACK2I7_RS00325 - 67665..68195 (+) 531 WP_003032280.1 FUSC family protein -
  ACK2I7_RS00330 - 68272..68631 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  ACK2I7_RS00335 glnA 68670..70016 (+) 1347 WP_003027006.1 type I glutamate--ammonia ligase -
  ACK2I7_RS00340 - 70205..70570 (+) 366 WP_003027003.1 DUF1033 family protein -
  ACK2I7_RS00345 comYA 70640..71581 (+) 942 WP_003027001.1 competence type IV pilus ATPase ComGA Machinery gene
  ACK2I7_RS00350 comYB 71523..72545 (+) 1023 WP_041783985.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACK2I7_RS00355 comYC 72542..72859 (+) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  ACK2I7_RS00360 comYD 72819..73247 (+) 429 WP_021001232.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACK2I7_RS00365 comGE/cglE 73219..73512 (+) 294 WP_021001233.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACK2I7_RS00370 comGF/cglF 73496..73933 (+) 438 WP_041783987.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACK2I7_RS00375 comGG 73914..74240 (+) 327 WP_021001234.1 competence type IV pilus minor pilin ComGG -
  ACK2I7_RS00380 comYH 74312..75265 (+) 954 WP_021001235.1 class I SAM-dependent methyltransferase Machinery gene
  ACK2I7_RS00385 - 75312..76511 (+) 1200 WP_021001236.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35907.12 Da        Isoelectric Point: 6.3128

>NTDB_id=1081678 ACK2I7_RS00345 WP_003027001.1 70640..71581(+) (comYA) [Streptococcus anginosus strain SFAD 40]
MVQNIAQAIICQAKKEQAQDIYFVPRENMYELYMRIGDERRFIQQYAFEEMAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YGDKKTSLRLSTVGDYRGYESLVIRLLHDEEAELKFWFAQIPELKERFKQRGLYLFSGPVGSGKTTLMHQLAQERFADQQ
IMSIEDPVEIKQAGMLQLQLNEAIGLTYESLIKLSLRHRPDLLIIGEIRDAETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVTEAELKIVLQGICYQRLIAKGGIVDFVSERYQEHEPSDWNKQIDQLYAAGHVTFEQAETEKIIHS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1081678 ACK2I7_RS00345 WP_003027001.1 70640..71581(+) (comYA) [Streptococcus anginosus strain SFAD 40]
ATGGTTCAAAACATTGCACAGGCTATTATTTGCCAAGCTAAAAAAGAGCAGGCTCAGGACATTTATTTTGTTCCAAGGGA
AAATATGTATGAGCTATACATGCGAATTGGAGATGAACGGCGCTTTATCCAACAGTATGCATTTGAAGAGATGGCAGCAG
TAATTAGTCATTTTAAGTTTACCGCTGGGATGAATGTCGGCGAAAAACGTAGAAGCCAGTTAGGATCTTGTGATTATCAA
TATGGTGATAAGAAAACGTCATTACGACTGTCAACAGTAGGGGATTATCGTGGATACGAAAGTCTGGTGATTCGTTTATT
GCATGATGAAGAGGCAGAGTTGAAGTTTTGGTTTGCTCAAATCCCAGAGTTAAAAGAACGCTTCAAACAACGAGGGCTTT
ATCTTTTTTCGGGACCGGTAGGAAGTGGTAAAACTACTCTCATGCACCAGTTGGCTCAAGAGCGTTTTGCCGATCAGCAA
ATCATGTCAATTGAAGATCCGGTTGAAATCAAACAAGCAGGGATGTTACAGCTGCAGCTGAACGAAGCGATTGGTTTAAC
TTATGAAAGTTTGATTAAACTTTCTCTTCGGCATCGACCAGATTTATTGATTATCGGAGAGATTCGTGATGCGGAGACAG
CAAGGGCAGTTGTTCGAGCTAGCTTAACGGGAGTGACTGTTTTTTCAACTATTCATGCTAAAAGCGTACGAGGTGTCTAT
GAACGGTTGCTGGAGTTGGGAGTGACAGAAGCAGAGCTGAAAATTGTTTTGCAAGGAATTTGCTACCAACGGTTAATTGC
GAAAGGAGGAATAGTGGATTTTGTCAGTGAAAGGTATCAAGAGCATGAGCCAAGTGACTGGAATAAGCAGATTGATCAGC
TTTATGCAGCAGGACATGTCACTTTTGAGCAGGCAGAAACGGAAAAAATTATCCATAGTTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

82.258

99.042

0.815
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.399

100

0.754
  comYA Streptococcus mutans UA159

64.309

99.361

0.639
  comYA Streptococcus mutans UA140

64.309

99.361

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.258

99.042

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

54.341

99.361

0.54
  comGA Latilactobacillus sakei subsp. sakei 23K

42.349

89.776

0.38

Multiple sequence alignment