Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   AAA995_RS09830 Genome accession   NZ_AP028877
Coordinates   1900280..1901221 (-) Length   313 a.a.
NCBI ID   WP_338173922.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 21P20     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1895280..1906221
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAA995_RS09790 (SP21P20_19140) comYH 1895772..1896725 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  AAA995_RS09795 - 1896786..1897378 (-) 593 Protein_1904 methyltransferase domain-containing protein -
  AAA995_RS09800 (SP21P20_19170) comGG/cglG 1897481..1897927 (-) 447 WP_001809944.1 competence type IV pilus minor pilin ComGG Machinery gene
  AAA995_RS09805 (SP21P20_19180) comGF/cglF 1897905..1898366 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  AAA995_RS09810 (SP21P20_19190) comGE/cglE 1898329..1898631 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  AAA995_RS09815 (SP21P20_19200) comGD/cglD 1898594..1899028 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  AAA995_RS09820 (SP21P20_19210) comGC/cglC 1898991..1899314 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  AAA995_RS09825 (SP21P20_19220) comGB/cglB 1899316..1900332 (-) 1017 WP_078130737.1 competence type IV pilus assembly protein ComGB Machinery gene
  AAA995_RS09830 (SP21P20_19230) comGA/cglA/cilD 1900280..1901221 (-) 942 WP_338173922.1 competence type IV pilus ATPase ComGA Machinery gene
  AAA995_RS09835 (SP21P20_19240) - 1901297..1901662 (-) 366 WP_000286415.1 DUF1033 family protein -
  AAA995_RS09840 (SP21P20_19250) - 1901813..1902871 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  AAA995_RS09845 (SP21P20_19260) nagA 1903034..1904185 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  AAA995_RS09850 (SP21P20_19270) - 1904338..1906155 (-) 1818 WP_001220842.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35492.43 Da        Isoelectric Point: 6.1829

>NTDB_id=107231 AAA995_RS09830 WP_338173922.1 1900280..1901221(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain 21P20]
MVQEIAQEIIRSAREKGTQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGKKRRSQLGSCDYA
YDQKMASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYGNLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFASRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=107231 AAA995_RS09830 WP_338173922.1 1900280..1901221(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain 21P20]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCAGCTCGGGAAAAAGGGACGCAGGATATTTATTTTGTCCCTAAGTT
AGACGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAAAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATGGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAACAGGACTTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGGAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAGCAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

98.403

100

0.984
  comGA/cglA/cilD Streptococcus pneumoniae D39

98.403

100

0.984
  comGA/cglA/cilD Streptococcus pneumoniae R6

98.403

100

0.984
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

98.403

100

0.984
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

95.527

100

0.955
  comYA Streptococcus gordonii str. Challis substr. CH1

77.742

99.042

0.77
  comYA Streptococcus mutans UA159

65.595

99.361

0.652
  comYA Streptococcus mutans UA140

65.595

99.361

0.652
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.581

99.042

0.62
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

99.681

0.546

Multiple sequence alignment