Detailed information NTG0107226

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: AAA995_RS09805
• Genome accession: NZ_AP028877
• Coordinates: 1897905..1898366 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250531.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 21P20
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1892905..1903366

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAA995_RS09770 (SP21P20_19110)	-	1893212..1894036 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
AAA995_RS09775 (SP21P20_19120)	rnpA	1894011..1894382 (-)	372	WP_000739246.1	ribonuclease P protein component	-
AAA995_RS09780	-	1894399..1894530 (-)	132	WP_000768904.1	hypothetical protein	-
AAA995_RS09785 (SP21P20_19130)	-	1894531..1895721 (-)	1191	WP_000167765.1	acetate kinase	-
AAA995_RS09790 (SP21P20_19140)	comYH	1895772..1896725 (-)	954	WP_000345126.1	class I SAM-dependent methyltransferase	Machinery gene
AAA995_RS09795	-	1896786..1897378 (-)	593	Protein_1904	methyltransferase domain-containing protein	-
AAA995_RS09800 (SP21P20_19170)	comGG/cglG	1897481..1897927 (-)	447	WP_001809944.1	competence type IV pilus minor pilin ComGG	Machinery gene
AAA995_RS09805 (SP21P20_19180)	comGF/cglF	1897905..1898366 (-)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
AAA995_RS09810 (SP21P20_19190)	comGE/cglE	1898329..1898631 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
AAA995_RS09815 (SP21P20_19200)	comGD/cglD	1898594..1899028 (-)	435	WP_033606693.1	competence type IV pilus minor pilin ComGD	Machinery gene
AAA995_RS09820 (SP21P20_19210)	comGC/cglC	1898991..1899314 (-)	324	WP_000738628.1	comG operon protein ComGC	Machinery gene
AAA995_RS09825 (SP21P20_19220)	comGB/cglB	1899316..1900332 (-)	1017	WP_078130737.1	competence type IV pilus assembly protein ComGB	Machinery gene
AAA995_RS09830 (SP21P20_19230)	comGA/cglA/cilD	1900280..1901221 (-)	942	WP_338173922.1	competence type IV pilus ATPase ComGA	Machinery gene
AAA995_RS09835 (SP21P20_19240)	-	1901297..1901662 (-)	366	WP_000286415.1	DUF1033 family protein	-
AAA995_RS09840 (SP21P20_19250)	-	1901813..1902871 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17849.37 Da
• Isoelectric Point: 6.4832

>NTDB_id=107226 AAA995_RS09805 WP_000250531.1 1897905..1898366(-) (comGF/cglF) [Streptococcus pneumoniae strain 21P20]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=107226 AAA995_RS09805 WP_000250531.1 1897905..1898366(-) (comGF/cglF) [Streptococcus pneumoniae strain 21P20]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae D39	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae R6	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae TIGR4	95.425	100	0.954
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915