Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   AAA982_RS09610 Genome accession   NZ_AP028601
Coordinates   1850982..1851923 (-) Length   313 a.a.
NCBI ID   WP_016398028.1    Uniprot ID   A0A0U0BVC9
Organism   Streptococcus pneumoniae strain PF1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1845982..1856923
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAA982_RS09570 (TKY113292_18620) comYH 1846469..1847422 (-) 954 WP_044813830.1 class I SAM-dependent methyltransferase Machinery gene
  AAA982_RS09575 - 1847483..1848077 (-) 595 Protein_1860 methyltransferase domain-containing protein -
  AAA982_RS09580 (TKY113292_18650) comGG/cglG 1848180..1848626 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  AAA982_RS09585 comGF/cglF 1848604..1849065 (-) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  AAA982_RS09590 (TKY113292_18670) comGE/cglE 1849028..1849330 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  AAA982_RS09595 (TKY113292_18680) comGD/cglD 1849293..1849697 (-) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  AAA982_RS09600 (TKY113292_18690) comGC/cglC 1849690..1850016 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  AAA982_RS09605 (TKY113292_18700) comGB/cglB 1850018..1851034 (-) 1017 WP_138028521.1 competence type IV pilus assembly protein ComGB Machinery gene
  AAA982_RS09610 (TKY113292_18710) comGA/cglA/cilD 1850982..1851923 (-) 942 WP_016398028.1 competence type IV pilus ATPase ComGA Machinery gene
  AAA982_RS09615 (TKY113292_18720) - 1851999..1852364 (-) 366 WP_000286415.1 DUF1033 family protein -
  AAA982_RS09620 (TKY113292_18730) - 1852515..1853573 (-) 1059 WP_000649473.1 zinc-dependent alcohol dehydrogenase family protein -
  AAA982_RS09625 (TKY113292_18740) nagA 1853736..1854887 (-) 1152 WP_001134454.1 N-acetylglucosamine-6-phosphate deacetylase -
  AAA982_RS09630 (TKY113292_18750) - 1855040..1856857 (-) 1818 WP_317649173.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35546.46 Da        Isoelectric Point: 6.0083

>NTDB_id=105845 AAA982_RS09610 WP_016398028.1 1850982..1851923(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain PF1]
MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKIASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFASRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=105845 AAA982_RS09610 WP_016398028.1 1850982..1851923(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain PF1]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCAGCTCGGAAAAAAGGGACGCAGGATATTTATTTTGTCCCTAAGTT
AGATGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATAGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACCTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAGCAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0U0BVC9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

99.681

100

0.997
  comGA/cglA/cilD Streptococcus pneumoniae D39

99.681

100

0.997
  comGA/cglA/cilD Streptococcus pneumoniae R6

99.681

100

0.997
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

99.681

100

0.997
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

96.166

100

0.962
  comYA Streptococcus gordonii str. Challis substr. CH1

78.065

99.042

0.773
  comYA Streptococcus mutans UA159

65.916

99.361

0.655
  comYA Streptococcus mutans UA140

65.916

99.361

0.655
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.581

99.042

0.62
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

99.681

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

42.642

84.665

0.361

Multiple sequence alignment