Detailed information NTG1043470

Bioinformatically predicted

Overview

• Name: comX/comX2
• Type: Regulator
• Locus tag: ACD269_RS00075
• Genome accession: NZ_CP168260
• Coordinates: 15676..16155 (+)
• Length: 159 a.a.
• NCBI ID: WP_373380539.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain FC2
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	14196..15452	15676..16155	flank	224

Gene organization within MGE regions

Location: 14196..16155

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACD269_RS00070 (ACD269_00070)	-	14196..15452 (-)	1257	WP_000436399.1	ISL3 family transposase	-
ACD269_RS00075 (ACD269_00075)	comX/comX2	15676..16155 (+)	480	WP_373380539.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 159 a.a.
• Molecular weight: 19899.55 Da
• Isoelectric Point: 7.3186

>NTDB_id=1043470 ACD269_RS00075 WP_373380539.1 15676..16155(+) (comX/comX2) [Streptococcus pneumoniae strain FC2]
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGEISYRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH

Nucleotide

• Length: 480 bp

>NTDB_id=1043470 ACD269_RS00075 WP_373380539.1 15676..16155(+) (comX/comX2) [Streptococcus pneumoniae strain FC2]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTTTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGATCAGTTATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/comX2	Streptococcus pneumoniae Rx1	99.371	100	0.994
comX/comX1	Streptococcus pneumoniae Rx1	99.371	100	0.994
comX/comX2	Streptococcus pneumoniae D39	99.371	100	0.994
comX/comX1	Streptococcus pneumoniae D39	99.371	100	0.994
comX/comX2	Streptococcus pneumoniae R6	99.371	100	0.994
comX/comX1	Streptococcus pneumoniae R6	99.371	100	0.994
comX/comX2	Streptococcus pneumoniae TIGR4	98.742	100	0.987
comX/comX1	Streptococcus pneumoniae TIGR4	98.742	100	0.987
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	91.824	100	0.918
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	91.824	100	0.918
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	90.506	99.371	0.899
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	88.608	99.371	0.881
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	48.077	98.113	0.472
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	48.077	98.113	0.472
comX/sigX	Streptococcus suis D9	45.033	94.969	0.428
comX/sigX	Streptococcus suis isolate S10	45.033	94.969	0.428
comX/sigX	Streptococcus suis P1/7	45.033	94.969	0.428
comX/sigX	Streptococcus mutans UA159	45.333	94.34	0.428
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	38.562	96.226	0.371
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	38.562	96.226	0.371
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	39.333	94.34	0.371
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	39.333	94.34	0.371
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	39.333	94.34	0.371
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	39.333	94.34	0.371