Detailed information    

insolico Bioinformatically predicted

Overview


Name   ssbA   Type   Machinery gene
Locus tag   ACB354_RS03095 Genome accession   NZ_CP167004
Coordinates   567785..568204 (+) Length   139 a.a.
NCBI ID   WP_021340323.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 28     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 558284..599779 567785..568204 within 0


Gene organization within MGE regions


Location: 558284..599779
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB354_RS03010 (ACB354_03010) - 558284..559450 (-) 1167 WP_011018152.1 site-specific integrase -
  ACB354_RS03015 (ACB354_03015) - 559628..561049 (-) 1422 WP_011018151.1 DUF4041 domain-containing protein -
  ACB354_RS03020 (ACB354_03020) - 561064..561450 (-) 387 WP_032463929.1 ImmA/IrrE family metallo-endopeptidase -
  ACB354_RS03025 (ACB354_03025) - 561434..561775 (-) 342 WP_011888679.1 helix-turn-helix transcriptional regulator -
  ACB354_RS03030 (ACB354_03030) - 561973..562185 (+) 213 WP_023078130.1 hypothetical protein -
  ACB354_RS03035 (ACB354_03035) - 562213..562932 (+) 720 WP_011018149.1 phage antirepressor KilAC domain-containing protein -
  ACB354_RS03040 (ACB354_03040) - 562936..563103 (+) 168 WP_021340232.1 hypothetical protein -
  ACB354_RS03045 (ACB354_03045) - 563342..563593 (+) 252 WP_021340237.1 AlpA family transcriptional regulator -
  ACB354_RS03050 (ACB354_03050) - 563624..563758 (+) 135 WP_021340229.1 hypothetical protein -
  ACB354_RS03055 (ACB354_03055) - 563774..564088 (+) 315 WP_021340228.1 helix-turn-helix domain-containing protein -
  ACB354_RS03060 (ACB354_03060) - 564102..565022 (+) 921 WP_021340238.1 phage replisome organizer N-terminal domain-containing protein -
  ACB354_RS03065 (ACB354_03065) - 565032..565874 (+) 843 WP_011018146.1 ATP-binding protein -
  ACB354_RS03070 (ACB354_03070) - 565874..566011 (+) 138 WP_011018145.1 hypothetical protein -
  ACB354_RS03075 (ACB354_03075) - 566022..566378 (+) 357 WP_011018144.1 HTH domain-containing protein -
  ACB354_RS03080 (ACB354_03080) - 566359..566613 (+) 255 WP_011018143.1 hypothetical protein -
  ACB354_RS03085 (ACB354_03085) - 566635..567117 (+) 483 WP_011018142.1 siphovirus Gp157 family protein -
  ACB354_RS03090 (ACB354_03090) - 567118..567792 (+) 675 WP_021340321.1 ERF family protein -
  ACB354_RS03095 (ACB354_03095) ssbA 567785..568204 (+) 420 WP_021340323.1 single-stranded DNA-binding protein Machinery gene
  ACB354_RS03100 (ACB354_03100) - 568210..568413 (+) 204 WP_011106686.1 hypothetical protein -
  ACB354_RS03105 (ACB354_03105) - 568413..568853 (+) 441 WP_011285574.1 RusA family crossover junction endodeoxyribonuclease -
  ACB354_RS03110 (ACB354_03110) - 568850..569206 (+) 357 WP_023078113.1 hypothetical protein -
  ACB354_RS03115 (ACB354_03115) - 569203..569454 (+) 252 WP_032462267.1 hypothetical protein -
  ACB354_RS03120 (ACB354_03120) - 569448..569732 (+) 285 WP_011018137.1 DUF3310 domain-containing protein -
  ACB354_RS03125 (ACB354_03125) - 569729..570133 (+) 405 WP_011018136.1 YopX family protein -
  ACB354_RS03130 (ACB354_03130) - 570130..570300 (+) 171 WP_011018135.1 hypothetical protein -
  ACB354_RS03135 (ACB354_03135) - 570297..570581 (+) 285 WP_011018134.1 hypothetical protein -
  ACB354_RS03140 (ACB354_03140) - 570583..571215 (+) 633 WP_011018133.1 N-6 DNA methylase -
  ACB354_RS03145 (ACB354_03145) - 571336..571707 (+) 372 WP_011018132.1 DUF1642 domain-containing protein -
  ACB354_RS03150 (ACB354_03150) - 571704..571970 (+) 267 WP_011018131.1 hypothetical protein -
  ACB354_RS03155 (ACB354_03155) - 572244..572684 (+) 441 WP_002990052.1 ArpU family phage packaging/lysis transcriptional regulator -
  ACB354_RS03160 (ACB354_03160) - 573148..573666 (+) 519 WP_011018130.1 ParB N-terminal domain-containing protein -
  ACB354_RS03165 (ACB354_03165) - 573645..574322 (+) 678 WP_011018129.1 ABC transporter ATP-binding protein -
  ACB354_RS03170 (ACB354_03170) - 574331..574714 (+) 384 WP_158296015.1 GNAT family N-acetyltransferase -
  ACB354_RS03175 (ACB354_03175) - 574775..575152 (+) 378 WP_002986841.1 ASCH domain-containing protein -
  ACB354_RS03180 (ACB354_03180) - 575194..575676 (+) 483 WP_281727461.1 hypothetical protein -
  ACB354_RS03185 (ACB354_03185) - 575759..576970 (+) 1212 WP_011184805.1 PBSX family phage terminase large subunit -
  ACB354_RS03190 (ACB354_03190) - 576984..578486 (+) 1503 WP_011184804.1 phage portal protein -
  ACB354_RS03195 (ACB354_03195) - 578491..579984 (+) 1494 WP_011018124.1 phage minor capsid protein -
  ACB354_RS03200 (ACB354_03200) - 579984..580211 (+) 228 WP_010922077.1 hypothetical protein -
  ACB354_RS03205 (ACB354_03205) - 580298..580564 (+) 267 WP_010922078.1 hypothetical protein -
  ACB354_RS03210 (ACB354_03210) - 580690..581304 (+) 615 WP_010922079.1 hypothetical protein -
  ACB354_RS03215 (ACB354_03215) - 581308..582126 (+) 819 WP_010922080.1 N4-gp56 family major capsid protein -
  ACB354_RS03220 (ACB354_03220) - 582180..582596 (+) 417 WP_011018123.1 hypothetical protein -
  ACB354_RS03225 (ACB354_03225) - 582586..582918 (+) 333 WP_010922082.1 minor capsid protein -
  ACB354_RS03230 (ACB354_03230) - 582918..583274 (+) 357 WP_010922083.1 minor capsid protein -
  ACB354_RS03235 (ACB354_03235) - 583271..583669 (+) 399 WP_011018121.1 minor capsid protein -
  ACB354_RS03240 (ACB354_03240) - 583669..584130 (+) 462 WP_011018120.1 phage tail tube protein -
  ACB354_RS03245 (ACB354_03245) - 584174..584608 (+) 435 WP_011018119.1 hypothetical protein -
  ACB354_RS03250 (ACB354_03250) - 584612..585193 (+) 582 WP_011018118.1 Gp15 family bacteriophage protein -
  ACB354_RS03255 (ACB354_03255) - 585183..588443 (+) 3261 WP_021340629.1 tape measure protein -
  ACB354_RS03260 (ACB354_03260) - 588440..589156 (+) 717 WP_011018116.1 distal tail protein Dit -
  ACB354_RS03265 (ACB354_03265) - 589153..591300 (+) 2148 WP_023078210.1 phage tail spike protein -
  ACB354_RS03270 (ACB354_03270) - 591300..592412 (+) 1113 WP_011184800.1 hyaluronoglucosaminidase -
  ACB354_RS03275 (ACB354_03275) - 592427..594442 (+) 2016 WP_011184799.1 gp58-like family protein -
  ACB354_RS03280 (ACB354_03280) - 594454..594882 (+) 429 WP_011184798.1 DUF1617 family protein -
  ACB354_RS03285 (ACB354_03285) - 594885..595502 (+) 618 WP_011018111.1 DUF1366 domain-containing protein -
  ACB354_RS03290 (ACB354_03290) - 595513..595812 (+) 300 WP_011184797.1 hypothetical protein -
  ACB354_RS03295 (ACB354_03295) - 595809..595994 (+) 186 WP_011184796.1 holin -
  ACB354_RS03300 (ACB354_03300) - 596107..597312 (+) 1206 WP_011184795.1 glucosaminidase domain-containing protein -
  ACB354_RS03305 (ACB354_03305) - 597461..597625 (+) 165 WP_021340366.1 hypothetical protein -
  ACB354_RS03310 (ACB354_03310) - 597658..598218 (+) 561 WP_011018106.1 GNAT family N-acetyltransferase -
  ACB354_RS03315 (ACB354_03315) sda 598359..599357 (-) 999 WP_032463908.1 streptodornase A -
  ACB354_RS03320 (ACB354_03320) prx 599597..599779 (+) 183 WP_011018104.1 hypothetical protein Regulator

Sequence


Protein


Download         Length: 139 a.a.        Molecular weight: 15611.30 Da        Isoelectric Point: 4.6702

>NTDB_id=1037036 ACB354_RS03095 WP_021340323.1 567785..568204(+) (ssbA) [Streptococcus pyogenes strain Isolate 28]
MINNIVLVGRMTKDAELRYTASQVAVATFTLAVNRRFKEQNGEREADFINCVIWRQSAENLANWAKKGALIGITGRIQTR
NYENQQGQRVYVTEVVAESFQMLESCNQQSGQGNSSQNDNSQPFGNSNPMDISDDDLPF

Nucleotide


Download         Length: 420 bp        

>NTDB_id=1037036 ACB354_RS03095 WP_021340323.1 567785..568204(+) (ssbA) [Streptococcus pyogenes strain Isolate 28]
ATGATTAACAACATTGTGCTAGTTGGTCGCATGACCAAGGACGCAGAGCTTCGCTATACAGCGAGTCAAGTAGCTGTAGC
TACGTTCACACTTGCGGTAAACCGCAGATTTAAAGAGCAAAACGGGGAGAGAGAAGCAGATTTCATTAACTGTGTTATCT
GGCGACAGTCTGCTGAAAATCTGGCAAACTGGGCTAAAAAAGGTGCCTTGATCGGAATTACAGGTCGTATCCAGACACGC
AACTACGAAAACCAACAAGGTCAACGTGTCTATGTAACAGAAGTTGTTGCAGAGAGTTTCCAAATGTTGGAAAGTTGCAA
TCAACAATCTGGTCAAGGTAACTCTTCGCAAAACGATAACAGTCAACCGTTTGGCAATTCAAACCCAATGGATATTTCAG
ATGATGATCTGCCGTTTTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Bacillus subtilis subsp. subtilis str. 168

54.857

100

0.691

  ssb Latilactobacillus sakei subsp. sakei 23K

52.941

100

0.647

  ssbB/cilA Streptococcus pneumoniae TIGR4

43.885

100

0.439

  ssbB Streptococcus sobrinus strain NIDR 6715-7

43.885

100

0.439

  ssbB/cilA Streptococcus pneumoniae Rx1

43.165

100

0.432

  ssbB/cilA Streptococcus mitis NCTC 12261

43.165

100

0.432

  ssbB/cilA Streptococcus pneumoniae D39

43.165

100

0.432

  ssbB/cilA Streptococcus pneumoniae R6

43.165

100

0.432

  ssbB/cilA Streptococcus mitis SK321

43.165

100

0.432

  ssbB Bacillus subtilis subsp. subtilis str. 168

55.769

74.82

0.417

  ssbA Streptococcus mutans UA159

41.007

100

0.41

  ssb Vibrio cholerae strain A1552

30.636

100

0.381


Multiple sequence alignment