Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   AB1395_RS00745 Genome accession   NZ_CP161815
Coordinates   135210..136163 (+) Length   317 a.a.
NCBI ID   WP_367783521.1    Uniprot ID   -
Organism   Streptococcus pluranimalium strain SS-15     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 130210..141163
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB1395_RS00735 (AB1395_00735) rpoC 130757..134389 (+) 3633 WP_367783519.1 DNA-directed RNA polymerase subunit beta' -
  AB1395_RS00740 (AB1395_00740) - 134767..135147 (+) 381 WP_218653889.1 DUF1033 family protein -
  AB1395_RS00745 (AB1395_00745) comYA 135210..136163 (+) 954 WP_367783521.1 competence type IV pilus ATPase ComGA Machinery gene
  AB1395_RS00750 (AB1395_00750) comYB 136087..137115 (+) 1029 WP_367784195.1 competence type IV pilus assembly protein ComGB Machinery gene
  AB1395_RS00755 (AB1395_00755) comYC 137116..137409 (+) 294 WP_367783523.1 competence type IV pilus major pilin ComGC Machinery gene
  AB1395_RS00760 (AB1395_00760) comGD 137390..137806 (+) 417 WP_278024843.1 competence type IV pilus minor pilin ComGD -
  AB1395_RS00765 (AB1395_00765) comGE 137778..138077 (+) 300 WP_367783525.1 competence type IV pilus minor pilin ComGE -
  AB1395_RS00770 (AB1395_00770) comYF 138055..138492 (+) 438 WP_367783527.1 competence type IV pilus minor pilin ComGF Machinery gene
  AB1395_RS00775 (AB1395_00775) comGG 138470..138871 (+) 402 WP_367783529.1 competence type IV pilus minor pilin ComGG -
  AB1395_RS00780 (AB1395_00780) comYH 138914..139867 (+) 954 WP_218653896.1 class I SAM-dependent methyltransferase Machinery gene
  AB1395_RS00785 (AB1395_00785) - 139928..141118 (+) 1191 WP_316605957.1 acetate kinase -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35679.66 Da        Isoelectric Point: 6.0490

>NTDB_id=1022567 AB1395_RS00745 WP_367783521.1 135210..136163(+) (comYA) [Streptococcus pluranimalium strain SS-15]
MVQDLAKELIVQAVEYEAQDVYIIPRKDDYDVFMRINDERRFIETHGFDRMASLISHFKFVAGMTVGEKRRSQLGSCDYD
IGSAKLVSLRLSTVGDYRGHESLVIRLLHDGRQELRYWFNGIRNIMAEFSSRGLYLFSGPTGSGKTTLMYQLLKETCKDK
QIISIEDPVEIKDDSILQLQLNEDIGMTYDSLIKLSLRHRPDVLVIGEIRDTQTAQAAIRASLTGATVFATIHAKSIPGV
YHRLIELGVSEDELNNSLAGICYQRLIGGGGLIDVAKDKFQDHTPSQWNQYLVELFKAGHLTEEQVKTESISASKAG

Nucleotide


Download         Length: 954 bp        

>NTDB_id=1022567 AB1395_RS00745 WP_367783521.1 135210..136163(+) (comYA) [Streptococcus pluranimalium strain SS-15]
ATGGTTCAAGATTTAGCAAAGGAACTGATTGTTCAGGCAGTCGAATATGAAGCTCAAGATGTTTATATCATTCCTCGAAA
GGATGATTACGATGTTTTTATGCGTATTAATGACGAGAGGAGATTTATTGAAACTCATGGCTTTGATCGGATGGCTAGTC
TTATTAGTCACTTTAAATTTGTGGCAGGAATGACTGTCGGGGAAAAGCGCCGAAGTCAACTAGGATCTTGTGATTATGAT
ATTGGTAGTGCTAAGCTAGTTTCTTTACGCCTCTCAACTGTTGGAGATTACCGAGGGCATGAGAGTTTGGTGATTCGTCT
GCTGCATGATGGGCGTCAGGAGTTACGCTATTGGTTCAATGGTATACGTAATATCATGGCAGAATTTAGTTCCAGAGGTC
TATATCTTTTTTCGGGACCGACTGGGAGCGGCAAAACGACTCTCATGTATCAATTGTTAAAGGAAACATGTAAAGATAAA
CAGATTATTTCTATTGAAGATCCGGTTGAAATTAAGGATGATAGCATTTTACAATTACAGCTTAATGAAGATATTGGTAT
GACTTACGATAGTCTGATTAAGTTGTCGTTGAGACATCGTCCAGATGTATTGGTTATTGGTGAAATTCGGGATACGCAAA
CAGCGCAAGCGGCTATTCGAGCTAGTTTGACTGGTGCTACAGTCTTTGCAACCATTCATGCCAAAAGTATTCCAGGAGTC
TATCACCGTTTGATAGAGCTGGGTGTTTCGGAGGATGAGCTAAACAATAGCCTGGCAGGGATTTGCTACCAACGTTTGAT
AGGAGGAGGTGGATTGATAGATGTGGCAAAAGACAAGTTCCAAGACCATACCCCAAGCCAGTGGAACCAATACTTGGTTG
AGCTTTTTAAAGCAGGACATCTCACTGAGGAGCAGGTCAAAACCGAGAGCATTAGCGCTTCAAAAGCAGGTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

64.241

99.685

0.64
  comYA Streptococcus mutans UA140

64.63

98.107

0.634
  comYA Streptococcus mutans UA159

64.63

98.107

0.634
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

63.548

97.792

0.621
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.42

99.054

0.618
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

62.102

99.054

0.615
  comGA/cglA/cilD Streptococcus pneumoniae D39

62.102

99.054

0.615
  comGA/cglA/cilD Streptococcus pneumoniae R6

62.102

99.054

0.615
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

62.102

99.054

0.615
  comGA Lactococcus lactis subsp. cremoris KW2

51.735

100

0.517

Multiple sequence alignment