Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00947  |
| T6SS type | Type Unknown |
| Strain | Escherichia coli strain PE050 |
| Replicon (GenBank) | chromosome I (KX118292) |
| Location | 1..4946 |
| Function | anti-bacterial |
| Comment | ETEC strains lacking vt1 or vgrG displayed a marked impairment in their capacity to kill Δvt1Δvti1 recipient cells, and vgrG and icmF are required for the antibacterial capacity of vt1+ strains. |
| References | [1] Jiale Ma, Min Sun, Zihao Pan, Chengping Lu, Huochun Yao et al (2018) Diverse Toxic Effectors Are Harbored by vgrG Islands for Interbacterial Antagonism in Type VI Secretion System. Biochim Biophys Acta Gen Subj. 1862(7):1635-1643. [PudMed:29674124] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | Vt6A | Vt6B | Vt6C | Vt6D |
| Number | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| T6CP016163 | Vt6A | Locus_01 (vt6A) | 1..2481 | + | 2481 | 1062685202 | Vgr family protein |
| T6CP016164 | Vt6B | Locus_02 (vt6B) | 2514..3167 | + | 654 | 1062685203 | VT6 amidase_2 toxin protein |
| T6CP016165 | Vt6C | Locus_03 (vt6C) | 3177..3626 | + | 450 | 1062685204 | VT6 immunity protein |
| T6CP016166 | Vt6D | Locus_04 (vt6D) | 3732..4946 | + | 1215 | 1062685205 | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| EFF01527 |
vt6B (VT1) | Tae | IMU00328 |
Escherichia coli strain PE050 | chromosome (KX118292) | 2514..3167 (+) | 1062685203 |
| EFF01531 |
vt6C (VTI1) | Tse | - | Escherichia coli strain PE050 | chromosome (KX118292) | 3177..3626 (+) | 1062685204 |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| IMU00328 |
vt6C (VTI1) | EFF01527 |
Escherichia coli strain PE050 | chromosome (KX118292) | 3177..3626 (+) | 1062685203 |
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|