Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00071  |
| T6SS type | Type i3 |
| Strain | Burkholderia mallei ATCC 23344 |
| Replicon (RefSeq) | chromosome II (NC_006349) |
| Location | 2076057..2104654 |
| Function | - |
| Comment | - |
| References | [1] Schell MA et al (2007) Type VI secretion is a major virulence determinant in Burkholderia mallei. Mol Microbiol. 64(6):1466-85. [PudMed:17555434] |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | TagJ | TssA | TssB | TssC | TssD | TssE | TssF | TssI | TssJ | TssK | TssL |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| BMA_RS24985 | 2071093..2071485 | - | 393 | WP_004196232.1 | helix-turn-helix domain-containing protein | ||
| BMA_RS24990 | 2071559..2072335 | - | 777 | WP_004187753.1 | NAD(P)H-dependent oxidoreductase | ||
| BMA_RS24995 | 2072431..2073324 | + | 894 | WP_004187634.1 | LysR family transcriptional regulator | ||
| BMA_RS25000 | 2073664..2075580 | + | 1917 | WP_004187822.1 | SMP-30/gluconolactonase/LRE family protein | ||
| BMA_RS25005 | 2076300..2076680 | - | 381 | WP_004200686.1 | DUF4150 domain-containing protein | ||
| BMA_RS25010 | 2076721..2077380 | - | 660 | WP_004187892.1 | DUF3540 domain-containing protein | ||
| BMA_RS25020 | 2077562..2078644 | - | 1083 | WP_004196236.1 | pentapeptide repeat-containing protein | ||
| BMA_RS25025 | 2078641..2081118 | - | 2478 | WP_004188576.1 | DUF2169 domain-containing protein | ||
| T6CP008463 | TssI | BMA_RS25030 (tssI) | 2081150..2083477 | - | 2328 | WP_004188373.1 | type VI secretion system tip protein VgrG |
| T6CP000604 | TssA | BMA_RS25035 | 2083549..2084652 | - | 1104 | WP_004196241.1 | type VI secretion system ImpA family N-terminal domain-containing protein |
| BMA_RS25040 (tssG) | 2084649..2085733 | - | 1085 | pseudogene | type VI secretion system baseplate subunit TssG | ||
| T6CP000605 | TssF | BMA_RS25045 (tssF) | 2085733..2087622 | - | 1890 | WP_004187986.1 | type VI secretion system baseplate subunit TssF |
| T6CP000606 | TssE | BMA_RS25050 (tssE) | 2087653..2088234 | - | 582 | WP_004187068.1 | type VI secretion system baseplate subunit TssE |
| T6CP012710 | TagJ | BMA_RS25055 | 2088221..2089186 | - | 966 | WP_004187921.1 | ImpE/SciE family protein |
| BMA_RS25060 | 2089183..2089929 | - | 747 | WP_004188539.1 | TagK domain-containing protein | ||
| BMA_RS25065 (tssH) | 2090435..2093358 | + | 2924 | pseudogene | type VI secretion system ATPase TssH | ||
| T6CP000607 | TssB | BMA_RS25070 (tssB) | 2093394..2093975 | + | 582 | WP_004196243.1 | type VI secretion system contractile sheath small subunit |
| T6CP000608 | TssC | BMA_RS25075 (tssC) | 2094010..2095509 | + | 1500 | WP_004188012.1 | type VI secretion system contractile sheath large subunit |
| T6CP000609 | TssD | BMA_RS25080 | 2095626..2096111 | + | 486 | WP_004188308.1 | type VI secretion system tube protein Hcp |
| T6CP000610 | TssJ | BMA_RS25085 (tssJ) | 2096218..2096721 | + | 504 | WP_004187276.1 | type VI secretion system lipoprotein TssJ |
| T6CP000611 | TssK | BMA_RS25090 (tssK) | 2096743..2098089 | + | 1347 | WP_004188743.1 | type VI secretion system baseplate subunit TssK |
| T6CP000612 | TssL | BMA_RS25095 (tssL) | 2098178..2099443 | + | 1266 | WP_004188530.1 | type VI secretion system protein TssL, long form |
| BMA_RS25100 (tssM) | 2099472..2103547 | + | 4076 | pseudogene | type VI secretion system membrane subunit TssM | ||
| BMA_RS25105 | 2103567..2103797 | + | 231 | WP_004188288.1 | hypothetical protein | ||
| BMA_RS25110 | 2104383..2105729 | + | 1347 | WP_004196246.1 | LysR family transcriptional regulator | ||
| BMA_RS25115 | 2105972..2106898 | - | 927 | WP_004187006.1 | catecholic dioxygenase | ||
| BMA_RS25120 | 2106953..2107924 | - | 972 | WP_004187502.1 | quinone oxidoreductase |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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