Detailed information of component protein


Summary

Component ID T6CP000612
Component protein type TssL
T6SS ID (Type) T6SS00071 insolico (Type i3)
Strain Burkholderia mallei ATCC 23344
Replicon chromosome II
Sequence Protein sequence (422 a.a.); Nucleotide sequence (1266 bp)
Reference
insolico Bioinformatics investigation has been performed on this T6SS
External database links

Locus tag (Gene) BMA_RS25095
Coordinate (Strand) 2098178..2099443 (+)
NCBI ID WP_004188530.1
RefSeq NC_006349
Uniprot ID -
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
DotU PF09850.11 3.5e-72 47..254
OmpA PF00691.22 1.3e-15 315..413
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-233 VHHPDISAPAPTFDSVAATLARREPAPAPAGEPPAARLAAIRLARNPLLEAARVLLRALADMPERLDRDDIPQLRLLLEQEVRLFQRLCEQANIRRDHMLGARYCLCTALDEAAMQTSWAQSASGNLGTWISEGLATSFHEDRQGGDKVYLLIGRLMNSPHEHIDLLEVIYRILSLGFEGRYRYEADGQRKHETVRQRLYNEIASQRGPVSVALSPHWQPGPRNRSAPFRDFP
Transmembrane helix 234-256 AWVTAAVLSLIALGLFGCFKYAL
Inside 257-421 STRSADVQQRIAAIARMAPPAAPAELRLATLLAGEIAAGTLSVEENARRSSVTFRGDAMFAPGAAGVNPAMGPLIRKIAAEIARVPGKVTVRGYTDNQPIKSRQFASNEALSEERATQVMQMLQSAGVPASRLEALGKGGAEPIGDNRTPQGRALNRRVEITVAR


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9541 - -


  Protein sequence: 422 a.a.    

>T6CP000612 NC_006349:2098178-2099443 [Burkholderia mallei ATCC 23344] [TssL]
VHHPDISAPAPTFDSVAATLARREPAPAPAGEPPAARLAAIRLARNPLLEAARVLLRALADMPERLDRDDIPQLRLLLEQ
EVRLFQRLCEQANIRRDHMLGARYCLCTALDEAAMQTSWAQSASGNLGTWISEGLATSFHEDRQGGDKVYLLIGRLMNSP
HEHIDLLEVIYRILSLGFEGRYRYEADGQRKHETVRQRLYNEIASQRGPVSVALSPHWQPGPRNRSAPFRDFPAWVTAAV
LSLIALGLFGCFKYALSTRSADVQQRIAAIARMAPPAAPAELRLATLLAGEIAAGTLSVEENARRSSVTFRGDAMFAPGA
AGVNPAMGPLIRKIAAEIARVPGKVTVRGYTDNQPIKSRQFASNEALSEERATQVMQMLQSAGVPASRLEALGKGGAEPI
GDNRTPQGRALNRRVEITVAR*

  Nucleotide sequence: 1266 bp    

>T6CP000612 NC_006349:2098178-2099443 [Burkholderia mallei ATCC 23344] [TssL]
GTGCATCATCCGGACATATCGGCTCCGGCCCCGACCTTCGATTCCGTCGCGGCGACGCTCGCGCGGCGCGAGCCGGCGCC
TGCGCCGGCCGGCGAGCCGCCCGCCGCGCGCCTCGCCGCGATCAGGCTCGCCCGCAACCCGCTGCTCGAAGCCGCGCGCG
TGCTGCTGCGGGCGCTCGCCGACATGCCCGAGCGGCTCGATCGCGACGACATTCCGCAATTGCGACTGCTGCTGGAACAG
GAGGTGCGCCTGTTCCAGCGGCTCTGCGAACAGGCGAACATCCGGCGCGACCACATGCTCGGCGCGCGCTACTGCCTGTG
CACCGCGCTCGACGAGGCGGCGATGCAGACGTCGTGGGCACAATCGGCGAGCGGCAATCTCGGCACGTGGATCAGCGAGG
GGCTCGCGACGTCGTTCCACGAGGATCGCCAGGGCGGAGACAAGGTCTATCTGCTGATCGGCCGGCTGATGAATTCGCCG
CACGAGCACATCGACCTGCTCGAAGTCATCTATCGAATCTTGAGCCTCGGCTTCGAGGGCCGCTACCGTTACGAAGCCGA
CGGCCAGCGCAAGCACGAGACCGTGCGCCAGCGGCTCTACAACGAGATCGCATCGCAGCGCGGGCCGGTGTCGGTCGCGC
TGTCGCCGCACTGGCAGCCCGGCCCCCGCAACAGGAGCGCGCCGTTTCGCGATTTCCCCGCGTGGGTCACGGCCGCCGTG
CTGTCGCTGATCGCGCTCGGGCTGTTCGGCTGCTTCAAGTACGCGCTGTCGACGCGCAGCGCCGACGTGCAGCAGCGGAT
CGCCGCGATCGCGCGGATGGCGCCGCCCGCCGCGCCGGCCGAGCTGCGCCTCGCGACGCTGCTCGCCGGCGAGATCGCGG
CAGGCACGCTCAGCGTCGAGGAAAACGCGCGCCGCAGCTCGGTGACGTTCCGCGGCGACGCGATGTTCGCGCCGGGCGCG
GCCGGCGTGAACCCGGCGATGGGGCCGCTCATCCGGAAAATCGCGGCCGAGATCGCGAGGGTGCCGGGCAAGGTGACGGT
GCGCGGCTACACCGACAATCAGCCGATCAAAAGCCGCCAGTTCGCGTCGAACGAGGCGCTATCCGAAGAGCGCGCGACGC
AGGTCATGCAGATGCTCCAGAGCGCGGGCGTGCCCGCGAGCCGCCTCGAGGCGCTCGGCAAGGGCGGCGCCGAGCCGATC
GGCGACAACCGGACCCCGCAGGGCCGCGCGCTGAACCGCCGCGTCGAAATCACGGTCGCGCGCTGA