Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   ABC804_RS00570 Genome accession   NZ_CP155536
Coordinates   92675..93337 (+) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain M264-3     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 87675..98337
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC804_RS00540 (ABC804_00540) tnpB 88133..88456 (+) 324 WP_000973415.1 IS66 family insertion sequence element accessory protein TnpB -
  ABC804_RS00545 (ABC804_00545) - 88611..88898 (-) 288 Protein_98 transposase -
  ABC804_RS00550 (ABC804_00550) - 88880..89409 (+) 530 Protein_99 transposase -
  ABC804_RS00555 (ABC804_00555) cysK 89484..90404 (-) 921 WP_000029867.1 cysteine synthase A -
  ABC804_RS00560 (ABC804_00560) - 90689..91324 (-) 636 WP_000395739.1 YigZ family protein -
  ABC804_RS00565 (ABC804_00565) comFA/cflA 91380..92678 (+) 1299 WP_000867612.1 DEAD/DEAH box helicase Machinery gene
  ABC804_RS00570 (ABC804_00570) comFC/cflB 92675..93337 (+) 663 WP_000649971.1 ComF family protein Machinery gene
  ABC804_RS00575 (ABC804_00575) raiA 93417..93965 (+) 549 WP_000599107.1 ribosome-associated translation inhibitor RaiA -
  ABC804_RS00580 (ABC804_00580) - 94101..96074 (+) 1974 WP_000715124.1 DHH family phosphoesterase -
  ABC804_RS00585 (ABC804_00585) rplI 96071..96523 (+) 453 WP_000864220.1 50S ribosomal protein L9 -
  ABC804_RS00590 (ABC804_00590) dnaB 96567..97919 (+) 1353 WP_000852486.1 replicative DNA helicase -
  ABC804_RS00595 (ABC804_00595) - 97921..98187 (+) 267 WP_001278167.1 Veg family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=997388 ABC804_RS00570 WP_000649971.1 92675..93337(+) (comFC/cflB) [Streptococcus pneumoniae strain M264-3]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=997388 ABC804_RS00570 WP_000649971.1 92675..93337(+) (comFC/cflB) [Streptococcus pneumoniae strain M264-3]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAACAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914

Multiple sequence alignment