Detailed information NTG0994461

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: AAYT23_RS07905
• Genome accession: NZ_CP154877
• Coordinates: 1558198..1558857 (+)
• Length: 219 a.a.
• NCBI ID: WP_000565605.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 20234295
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1553198..1563857

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAYT23_RS07870 (AAYT23_07850)	mgaSpn	1553809..1555290 (-)	1482	WP_001205280.1	virulence factor transcriptional regulator MgaSpn	-
AAYT23_RS07875 (AAYT23_07855)	-	1555733..1555897 (+)	165	WP_001809002.1	GlsB/YeaQ/YmgE family stress response membrane protein	-
AAYT23_RS07880 (AAYT23_07860)	amaP	1555981..1556547 (+)	567	WP_000030213.1	alkaline shock response membrane anchor protein AmaP	-
AAYT23_RS07885 (AAYT23_07865)	-	1556559..1556729 (+)	171	WP_000455066.1	DUF2273 domain-containing protein	-
AAYT23_RS07890 (AAYT23_07870)	-	1556768..1557376 (+)	609	WP_000064115.1	Asp23/Gls24 family envelope stress response protein	-
AAYT23_RS07895 (AAYT23_07875)	-	1557407..1557610 (+)	204	WP_000109961.1	CsbD family protein	-
AAYT23_RS07900 (AAYT23_07880)	-	1557682..1558128 (-)	447	WP_000155416.1	GNAT family N-acetyltransferase	-
AAYT23_RS07905 (AAYT23_07885)	cclA/cilC	1558198..1558857 (+)	660	WP_000565605.1	prepilin peptidase	Machinery gene
AAYT23_RS07910 (AAYT23_07890)	-	1558909..1560060 (-)	1152	WP_000481750.1	helix-turn-helix domain-containing protein	-
AAYT23_RS07915 (AAYT23_07895)	-	1560075..1560749 (-)	675	WP_000678278.1	hypothetical protein	-
AAYT23_RS07920 (AAYT23_07900)	-	1561025..1561135 (+)	111	Protein_1565	prepilin peptidase	-
AAYT23_RS07925 (AAYT23_07905)	trpA	1561107..1561883 (-)	777	WP_001127043.1	tryptophan synthase subunit alpha	-
AAYT23_RS07930 (AAYT23_07910)	trpB	1561876..1563099 (-)	1224	WP_000331295.1	tryptophan synthase subunit beta	-
AAYT23_RS07935 (AAYT23_07915)	-	1563077..1563676 (-)	600	WP_000169892.1	phosphoribosylanthranilate isomerase	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24793.89 Da
• Isoelectric Point: 7.6166

>NTDB_id=994461 AAYT23_RS07905 WP_000565605.1 1558198..1558857(+) (cclA/cilC) [Streptococcus pneumoniae strain 20234295]
MIDIYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=994461 AAYT23_RS07905 WP_000565605.1 1558198..1558857(+) (cclA/cilC) [Streptococcus pneumoniae strain 20234295]
ATGATTGATATTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGAGCAT
CTATGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae Rx1	95.89	100	0.959
cclA/cilC	Streptococcus pneumoniae D39	95.89	100	0.959
cclA/cilC	Streptococcus pneumoniae R6	95.89	100	0.959
cclA/cilC	Streptococcus mitis SK321	93.151	100	0.932
cclA/cilC	Streptococcus mitis NCTC 12261	87.671	100	0.877