Detailed information NTG0989152

Bioinformatically predicted

Overview

• Name: comE
• Type: Regulator
• Locus tag: AAFQ93_RS01940
• Genome accession: NZ_CP152419
• Coordinates: 397402..398154 (+)
• Length: 250 a.a.
• NCBI ID: WP_049530388.1
• Uniprot ID: -
• Organism: Streptococcus nidrosiense strain SO-23-1
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 392402..403154

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAFQ93_RS01910 (AAFQ93_01915)	spo0J	392984..393742 (-)	759	WP_045762401.1	ParB/RepB/Spo0J family partition protein	Regulator
AAFQ93_RS01915 (AAFQ93_01920)	htrA	393799..394983 (-)	1185	WP_000793272.1	S1C family serine protease	Regulator
AAFQ93_RS01920 (AAFQ93_01925)	rlmH	395167..395646 (+)	480	WP_000695942.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
AAFQ93_RS01930 (AAFQ93_01935)	comC	395929..396063 (+)	135	WP_080936286.1	competence-stimulating peptide ComC	-
AAFQ93_RS01935 (AAFQ93_01940)	comD	396086..397405 (+)	1320	WP_045762404.1	competence system sensor histidine kinase ComD	Regulator
AAFQ93_RS01940 (AAFQ93_01945)	comE	397402..398154 (+)	753	WP_049530388.1	competence system response regulator transcription factor ComE	Regulator
AAFQ93_RS01950 (AAFQ93_01955)	-	398561..399103 (-)	543	WP_001158257.1	TetR/AcrR family transcriptional regulator	-
AAFQ93_RS01955 (AAFQ93_01960)	-	399232..401895 (+)	2664	WP_223140364.1	YhgE/Pip domain-containing protein	-

Sequence

Protein

• Length: 250 a.a.
• Molecular weight: 29634.07 Da
• Isoelectric Point: 8.5500

>NTDB_id=989152 AAFQ93_RS01940 WP_049530388.1 397402..398154(+) (comE) [Streptococcus nidrosiense strain SO-23-1]
MKVLILEDIIEHQVRLETTLNKISKETNIPISYKTTGKVREFMEYVEHDEVNQLYFLDIDINGIERKGFEVAQFIRHRNP
YAIIVFITSRSEFATLTYKYKVSALDFIDKETSDQVFKNRVADCVLYTKTTLLENQSVVDYFDYSYKGNDLCIPYHDILY
IETTGTSHKLRIVGKNFAKEFYGTMTDIQEKDKETQRFYLAHKSFLVNIGNVREIDRKKMEVVFYEDHRCPISRLKTKKL
RELMAKNQKK

Nucleotide

• Length: 753 bp

>NTDB_id=989152 AAFQ93_RS01940 WP_049530388.1 397402..398154(+) (comE) [Streptococcus nidrosiense strain SO-23-1]
ATGAAAGTATTGATTTTAGAAGATATTATAGAACACCAAGTAAGGTTGGAAACAACTCTAAATAAAATTTCTAAGGAAAC
AAATATTCCTATCTCCTATAAAACAACAGGAAAAGTAAGAGAGTTTATGGAATATGTAGAGCATGATGAAGTCAATCAGC
TTTATTTTCTAGATATTGATATCAATGGGATTGAGAGAAAAGGATTTGAGGTTGCTCAATTTATTCGCCATCGCAATCCT
TATGCGATTATTGTTTTTATTACAAGTCGATCTGAATTTGCTACTTTGACTTATAAATACAAAGTTTCAGCATTGGATTT
CATTGATAAAGAAACCAGTGATCAAGTTTTTAAAAATAGAGTTGCCGACTGTGTGCTTTACACTAAGACTACTTTACTTG
AAAACCAATCAGTCGTTGATTATTTTGATTATAGTTATAAAGGAAATGATCTTTGTATTCCTTATCATGATATTCTCTAC
ATTGAAACAACGGGAACTTCTCATAAATTACGAATTGTAGGTAAGAATTTTGCAAAAGAATTCTATGGAACAATGACAGA
TATTCAAGAAAAGGATAAGGAAACCCAACGTTTTTATCTAGCTCACAAGTCATTTTTAGTCAATATTGGTAATGTGAGAG
AAATTGATCGTAAAAAAATGGAAGTTGTATTTTATGAAGATCATCGTTGTCCTATCTCTCGCCTAAAAACTAAAAAATTG
AGAGAACTAATGGCTAAAAACCAAAAAAAGTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-120)

• LytTr DNA-binding domain (LytTR) (152-244)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Streptococcus mitis NCTC 12261	79.6	100	0.796
comE	Streptococcus infantis strain Atu-4	79.2	100	0.792
comE	Streptococcus mitis SK321	79.2	100	0.792
comE	Streptococcus pneumoniae Rx1	79.2	100	0.792
comE	Streptococcus pneumoniae D39	79.2	100	0.792
comE	Streptococcus pneumoniae R6	79.2	100	0.792
comE	Streptococcus pneumoniae TIGR4	79.2	100	0.792
comE/comE2	Streptococcus gordonii strain NCTC7865	61.6	100	0.616
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	61.6	100	0.616
comE/blpR	Streptococcus mutans UA159	40.079	100	0.404