Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   AAFQ93_RS01935 Genome accession   NZ_CP152419
Coordinates   396086..397405 (+) Length   439 a.a.
NCBI ID   WP_045762404.1    Uniprot ID   -
Organism   Streptococcus nidrosiense strain SO-23-1     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 391086..402405
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAFQ93_RS01905 (AAFQ93_01910) dnaA 391407..392762 (-) 1356 WP_045762400.1 chromosomal replication initiator protein DnaA -
  AAFQ93_RS01910 (AAFQ93_01915) spo0J 392984..393742 (-) 759 WP_045762401.1 ParB/RepB/Spo0J family partition protein Regulator
  AAFQ93_RS01915 (AAFQ93_01920) htrA 393799..394983 (-) 1185 WP_000793272.1 S1C family serine protease Regulator
  AAFQ93_RS01920 (AAFQ93_01925) rlmH 395167..395646 (+) 480 WP_000695942.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  AAFQ93_RS01930 (AAFQ93_01935) comC 395929..396063 (+) 135 WP_080936286.1 competence-stimulating peptide ComC -
  AAFQ93_RS01935 (AAFQ93_01940) comD 396086..397405 (+) 1320 WP_045762404.1 competence system sensor histidine kinase ComD Regulator
  AAFQ93_RS01940 (AAFQ93_01945) comE 397402..398154 (+) 753 WP_049530388.1 competence system response regulator transcription factor ComE Regulator
  AAFQ93_RS01950 (AAFQ93_01955) - 398561..399103 (-) 543 WP_001158257.1 TetR/AcrR family transcriptional regulator -
  AAFQ93_RS01955 (AAFQ93_01960) - 399232..401895 (+) 2664 WP_223140364.1 YhgE/Pip domain-containing protein -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 51195.98 Da        Isoelectric Point: 7.9022

>NTDB_id=989151 AAFQ93_RS01935 WP_045762404.1 396086..397405(+) (comD) [Streptococcus nidrosiense strain SO-23-1]
MNLFGLVIAIVYVFIISKIHEWVCKATRKDQYFFSLYIFLIPLVLEIILYFLKLDSFSLSKFLFPFLLFGYFVGFKKYEK
SKGIFISLLFSLLYNSTNNFLSVTLSSITGDEFALKYNNYFSLFILILTYLVIKVVVSYFHLEFKYFDKDYLYPFLKKVL
FAFIFLHVVSFTSDIVSTIRHLNGFGSILSSIVFVGLLLTFFSMNSHKVQIEKEIELEQKKFEQKHLQTYTDEIVTLYNE
IRGFRHDYTGMLVSLRMAIESKDLQEIDRVYSEVLVKANQKLRSDKYTYFDLNNIEDSALRSLIAQSIVNAKTNDVEYTL
EVKDIITPLSMELLDLVRVMSVLLNNAVEGAVESYQKQLEVAIIKLDLETLVVIQNSCKKRKVKSEDLFELGFSTKGRHR
GLGLNNVKEILGKYDNVILETEIDNDVFKQVIRFKRELI

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=989151 AAFQ93_RS01935 WP_045762404.1 396086..397405(+) (comD) [Streptococcus nidrosiense strain SO-23-1]
ATGAATTTATTCGGATTAGTAATTGCTATTGTTTATGTTTTTATTATTAGTAAAATTCATGAATGGGTTTGTAAAGCAAC
TAGAAAAGACCAATATTTTTTTAGTCTTTATATATTTCTAATACCATTAGTATTGGAAATAATTCTCTATTTCTTGAAAT
TAGATAGTTTTAGTTTGTCTAAATTTTTATTTCCTTTCCTCCTATTTGGTTACTTTGTTGGATTTAAGAAGTATGAGAAA
TCTAAGGGAATTTTTATCAGTCTATTATTTTCTCTTTTATATAATAGTACTAATAACTTTTTATCAGTAACCTTATCATC
TATTACAGGAGATGAGTTTGCATTGAAGTATAACAATTATTTTTCTCTATTTATCCTGATCTTAACTTATTTGGTTATTA
AAGTTGTTGTGTCTTATTTCCATCTCGAATTTAAATATTTTGATAAAGACTATCTATATCCTTTTCTGAAGAAAGTGCTC
TTTGCATTTATTTTTCTACACGTTGTCTCTTTCACTTCAGATATTGTGAGTACGATTCGTCACTTAAATGGTTTTGGAAG
TATTTTATCATCCATTGTTTTTGTTGGCCTACTTTTGACTTTTTTCTCCATGAATTCTCATAAAGTTCAGATAGAAAAAG
AGATTGAATTGGAACAAAAGAAGTTTGAGCAAAAACATTTACAAACTTACACGGATGAGATTGTTACTTTATATAATGAA
ATTCGTGGTTTTCGCCATGATTATACAGGCATGCTTGTCAGCTTAAGAATGGCGATCGAAAGTAAAGATTTACAAGAAAT
TGACAGAGTTTACAGTGAAGTACTTGTAAAGGCGAATCAAAAATTACGTTCAGACAAGTATACCTATTTCGATTTGAACA
ATATTGAGGATTCAGCACTTCGTAGTTTAATTGCCCAATCTATTGTCAATGCGAAAACTAATGATGTAGAGTACACATTA
GAGGTAAAAGATATTATTACACCTTTATCTATGGAATTGTTAGATTTAGTGCGCGTGATGAGCGTTCTGCTCAATAATGC
TGTTGAAGGGGCAGTTGAAAGCTATCAAAAACAACTAGAGGTAGCTATTATCAAGTTGGATCTTGAAACCCTAGTTGTCA
TCCAAAACTCTTGTAAAAAAAGAAAGGTAAAATCCGAAGATTTATTTGAATTAGGATTTTCAACTAAAGGAAGACATAGA
GGACTTGGACTTAATAATGTTAAAGAAATTTTAGGAAAATATGACAATGTTATTTTAGAAACAGAAATTGATAATGATGT
ATTTAAACAAGTGATTAGATTTAAGAGGGAACTGATATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(331-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis SK321

67.654

100

0.677
  comD Streptococcus mitis NCTC 12261

67.654

100

0.677
  comD/comD2 Streptococcus pneumoniae TIGR4

66.515

100

0.665
  comD/comD1 Streptococcus pneumoniae R6

66.287

100

0.663
  comD/comD1 Streptococcus pneumoniae Rx1

66.287

100

0.663
  comD/comD1 Streptococcus pneumoniae D39

66.287

100

0.663
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

48.413

86.105

0.417
  comD/comD2 Streptococcus gordonii strain NCTC7865

48.404

85.649

0.415

Multiple sequence alignment