Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   NST80_RS09785 Genome accession   NZ_CP152039
Coordinates   2079763..2080704 (-) Length   313 a.a.
NCBI ID   WP_048674224.1    Uniprot ID   -
Organism   Streptococcus sp. FSL K6-1323     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2074763..2085704
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NST80_RS09745 (NST80_09745) - 2074838..2076031 (-) 1194 WP_048674220.1 acetate kinase -
  NST80_RS09750 (NST80_09750) comYH 2076088..2077044 (-) 957 WP_002887012.1 class I SAM-dependent methyltransferase Machinery gene
  NST80_RS09755 (NST80_09755) comGG 2077089..2077406 (-) 318 WP_021144683.1 competence type IV pilus minor pilin ComGG -
  NST80_RS09760 (NST80_09760) comYF 2077384..2077821 (-) 438 WP_002887014.1 competence type IV pilus minor pilin ComGF Machinery gene
  NST80_RS09765 (NST80_09765) comGE 2077808..2078038 (-) 231 WP_013991265.1 competence type IV pilus minor pilin ComGE -
  NST80_RS09770 (NST80_09770) comYD 2078070..2078498 (-) 429 WP_014632541.1 competence type IV pilus minor pilin ComGD Machinery gene
  NST80_RS09775 (NST80_09775) comYC 2078458..2078772 (-) 315 WP_037611125.1 competence type IV pilus major pilin ComGC Machinery gene
  NST80_RS09780 (NST80_09780) comYB 2078781..2079881 (-) 1101 WP_129852292.1 competence type IV pilus assembly protein ComGB Machinery gene
  NST80_RS09785 (NST80_09785) comGA/cglA/cilD 2079763..2080704 (-) 942 WP_048674224.1 competence type IV pilus ATPase ComGA Machinery gene
  NST80_RS09790 (NST80_09790) - 2080785..2081147 (-) 363 WP_002887019.1 DUF1033 family protein -
  NST80_RS09795 (NST80_09795) rpoC 2081310..2084948 (-) 3639 WP_002887020.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35299.31 Da        Isoelectric Point: 5.7041

>NTDB_id=986352 NST80_RS09785 WP_048674224.1 2079763..2080704(-) (comGA/cglA/cilD) [Streptococcus sp. FSL K6-1323]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGQRVSLRLSTVGDYRGLESLVIRVLHSERRELVYWNQGIQPIMDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSVSGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSTSWNQQLEGLVKQGYLTEGDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=986352 NST80_RS09785 WP_048674224.1 2079763..2080704(-) (comGA/cglA/cilD) [Streptococcus sp. FSL K6-1323]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTACGAGCTCTATATGCGAGTTGGCCAAGAGAGGAGATTAATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTAGGTTCCTGTGACTATGAT
TGTGGTGATGGTCAAAGGGTTTCTCTGCGTTTGTCTACCGTTGGGGATTATCGCGGCTTAGAAAGTTTAGTTATTCGTGT
TCTACATTCTGAACGTCGAGAATTAGTGTACTGGAATCAAGGAATCCAGCCTATTATGGATGCTTTGGATTATCGTGGCT
TATATCTCTTTGCAGGTCCCGTTGGTTCTGGAAAGACTACGCTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTGATTTCGATTGAGGACCCTGTGGAAATTAAACAGGATAATGTCTTGCAACTCCAGGTGAATCAAGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCATTACGTCACCGCCCGGATGTTTTGATTATTGGAGAAATTCGAGATAAGGAGA
CTGCTCGAGCGGTTATTAGAGCTAGTCTGACGGGAGTTACTGTTCTTTCAACTATTCACGCAAAGAGTGTGTCAGGTGTT
TATGAGCGTCTTCTGGACCTTGGTGTAGATAAGTCCGAGTTGGATAATGCTCTTCAAGGGATTGCCTACATGCGTCTGAT
TAAGGGAGGAGGTGTGATAGATTTTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAGCAGTTGGAAG
GCTTGGTTAAACAAGGATATCTCACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.916

99.361

0.655
  comYA Streptococcus mutans UA159

65.176

100

0.652
  comYA Streptococcus mutans UA140

65.176

100

0.652
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.63

99.361

0.642
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.897

99.681

0.607
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

41.697

86.581

0.361

Multiple sequence alignment