Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   NST80_RS09750 Genome accession   NZ_CP152039
Coordinates   2076088..2077044 (-) Length   318 a.a.
NCBI ID   WP_002887012.1    Uniprot ID   A0A1F2HRB9
Organism   Streptococcus sp. FSL K6-1323     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2071088..2082044
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NST80_RS09720 (NST80_09720) tnpA 2071782..2072255 (-) 474 WP_342504605.1 IS200/IS605 family transposase -
  NST80_RS09725 (NST80_09725) - 2072415..2073085 (-) 671 Protein_1860 type II CAAX endopeptidase family protein -
  NST80_RS09730 (NST80_09730) - 2073198..2073644 (-) 447 WP_104021398.1 CAAX protease -
  NST80_RS09735 (NST80_09735) - 2073722..2074378 (-) 657 WP_265107593.1 type II CAAX endopeptidase family protein -
  NST80_RS09740 (NST80_09740) - 2074390..2074587 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  NST80_RS09745 (NST80_09745) - 2074838..2076031 (-) 1194 WP_048674220.1 acetate kinase -
  NST80_RS09750 (NST80_09750) comYH 2076088..2077044 (-) 957 WP_002887012.1 class I SAM-dependent methyltransferase Machinery gene
  NST80_RS09755 (NST80_09755) comGG 2077089..2077406 (-) 318 WP_021144683.1 competence type IV pilus minor pilin ComGG -
  NST80_RS09760 (NST80_09760) comYF 2077384..2077821 (-) 438 WP_002887014.1 competence type IV pilus minor pilin ComGF Machinery gene
  NST80_RS09765 (NST80_09765) comGE 2077808..2078038 (-) 231 WP_013991265.1 competence type IV pilus minor pilin ComGE -
  NST80_RS09770 (NST80_09770) comYD 2078070..2078498 (-) 429 WP_014632541.1 competence type IV pilus minor pilin ComGD Machinery gene
  NST80_RS09775 (NST80_09775) comYC 2078458..2078772 (-) 315 WP_037611125.1 competence type IV pilus major pilin ComGC Machinery gene
  NST80_RS09780 (NST80_09780) comYB 2078781..2079881 (-) 1101 WP_129852292.1 competence type IV pilus assembly protein ComGB Machinery gene
  NST80_RS09785 (NST80_09785) comGA/cglA/cilD 2079763..2080704 (-) 942 WP_048674224.1 competence type IV pilus ATPase ComGA Machinery gene
  NST80_RS09790 (NST80_09790) - 2080785..2081147 (-) 363 WP_002887019.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 35760.65 Da        Isoelectric Point: 4.3805

>NTDB_id=986347 NST80_RS09750 WP_002887012.1 2076088..2077044(-) (comYH) [Streptococcus sp. FSL K6-1323]
MNFEAIETAFELLLENVQTIENDLGTHAYDALIEQNSYYLGAEVANEVIIKNNEKLRALNLSKEEWRRAFQFLFIKLGQL
EALQANHQFTPDAIGFIILYLLEGLTKDDQLDVLEIGSGTGNLAETLLNNSQKTLNYMGMEVDDLLIDLSASIADVVNSS
AVYIQEDAVRPHILKESDVIISDLPVGYYPNDEIASRFKVAATGEHTYAHHLLMEQSLKYLKKDGIAILLAPTNLLTSPQ
SDLLKKWLSGYADIIAVITLPEAAFGNKHNMKSIFVLKKQTENAPETFVYPLSDLQNPEVLKDFTENFQKWKSDNSIF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=986347 NST80_RS09750 WP_002887012.1 2076088..2077044(-) (comYH) [Streptococcus sp. FSL K6-1323]
ATGAATTTTGAAGCAATTGAGACAGCCTTTGAGCTGTTGTTAGAAAATGTCCAAACCATTGAAAATGATCTTGGAACCCA
TGCTTACGATGCGCTTATTGAGCAAAATTCCTATTATTTGGGGGCTGAGGTAGCTAATGAAGTCATCATCAAAAACAACG
AGAAATTACGTGCCCTTAATCTAAGCAAAGAGGAGTGGCGTCGTGCTTTTCAGTTCTTGTTTATCAAGCTAGGGCAATTG
GAAGCCTTACAAGCCAATCACCAGTTTACACCTGATGCTATTGGATTTATCATCCTCTACCTACTCGAAGGTTTGACCAA
GGACGACCAATTAGATGTTTTGGAGATTGGTTCGGGGACAGGAAACTTGGCTGAAACTCTTCTAAATAATAGTCAGAAAA
CCCTTAATTATATGGGAATGGAAGTTGACGATCTTCTTATCGATTTGTCAGCTAGTATTGCTGATGTGGTGAATTCAAGT
GCAGTTTACATTCAAGAAGATGCTGTTCGACCACATATTCTCAAAGAGAGTGATGTTATTATTAGTGACCTACCTGTTGG
TTACTACCCTAATGATGAAATTGCGAGTCGTTTCAAGGTTGCAGCAACCGGTGAACACACCTATGCCCATCACCTTCTCA
TGGAGCAATCACTCAAGTACCTGAAGAAAGATGGTATTGCTATTCTTTTGGCACCAACTAATCTTTTGACAAGCCCACAA
AGTGATTTGCTTAAGAAATGGCTATCAGGATATGCTGATATTATTGCCGTTATCACTCTTCCAGAAGCAGCTTTTGGCAA
TAAACATAACATGAAGTCTATCTTTGTGCTTAAAAAACAAACTGAAAATGCTCCTGAGACCTTCGTTTATCCACTTAGTG
ATTTGCAAAACCCAGAGGTCCTCAAAGATTTTACAGAGAATTTCCAAAAATGGAAATCAGATAATTCCATTTTCTAG

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-295)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1F2HRB9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

70.476

99.057

0.698
  comYH Streptococcus mutans UA140

70.476

99.057

0.698

Multiple sequence alignment