Detailed information NTG0986348

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: NST80_RS09760
• Genome accession: NZ_CP152039
• Coordinates: 2077384..2077821 (-)
• Length: 145 a.a.
• NCBI ID: WP_002887014.1
• Uniprot ID: A0A1V0GF29
• Organism: Streptococcus sp. FSL K6-1323
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2072384..2082821

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NST80_RS09725 (NST80_09725)	-	2072415..2073085 (-)	671	Protein_1860	type II CAAX endopeptidase family protein	-
NST80_RS09730 (NST80_09730)	-	2073198..2073644 (-)	447	WP_104021398.1	CAAX protease	-
NST80_RS09735 (NST80_09735)	-	2073722..2074378 (-)	657	WP_265107593.1	type II CAAX endopeptidase family protein	-
NST80_RS09740 (NST80_09740)	-	2074390..2074587 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
NST80_RS09745 (NST80_09745)	-	2074838..2076031 (-)	1194	WP_048674220.1	acetate kinase	-
NST80_RS09750 (NST80_09750)	comYH	2076088..2077044 (-)	957	WP_002887012.1	class I SAM-dependent methyltransferase	Machinery gene
NST80_RS09755 (NST80_09755)	comGG	2077089..2077406 (-)	318	WP_021144683.1	competence type IV pilus minor pilin ComGG	-
NST80_RS09760 (NST80_09760)	comYF	2077384..2077821 (-)	438	WP_002887014.1	competence type IV pilus minor pilin ComGF	Machinery gene
NST80_RS09765 (NST80_09765)	comGE	2077808..2078038 (-)	231	WP_013991265.1	competence type IV pilus minor pilin ComGE	-
NST80_RS09770 (NST80_09770)	comYD	2078070..2078498 (-)	429	WP_014632541.1	competence type IV pilus minor pilin ComGD	Machinery gene
NST80_RS09775 (NST80_09775)	comYC	2078458..2078772 (-)	315	WP_037611125.1	competence type IV pilus major pilin ComGC	Machinery gene
NST80_RS09780 (NST80_09780)	comYB	2078781..2079881 (-)	1101	WP_129852292.1	competence type IV pilus assembly protein ComGB	Machinery gene
NST80_RS09785 (NST80_09785)	comGA/cglA/cilD	2079763..2080704 (-)	942	WP_048674224.1	competence type IV pilus ATPase ComGA	Machinery gene
NST80_RS09790 (NST80_09790)	-	2080785..2081147 (-)	363	WP_002887019.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16155.57 Da
• Isoelectric Point: 8.4658

>NTDB_id=986348 NST80_RS09760 WP_002887014.1 2077384..2077821(-) (comYF) [Streptococcus sp. FSL K6-1323]
MSLNSKVRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVKQQESQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQDLAFGLSSATDFRKTNADGRGYQPMLFNVKASTISQNNQIVTIQVTLKNGLQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=986348 NST80_RS09760 WP_002887014.1 2077384..2077821(-) (comYF) [Streptococcus sp. FSL K6-1323]
ATGTCTCTCAATAGCAAGGTTCGTGCTTTTACCCTCTTGGAGTGTCTAGTGGCCTTGTTGGTGATTGCTGGTTCAGTTCA
AGTTTATCAAGGTCTGACCACAGTATTGGTGAGCAATGTTAAGCAGGTCAAGCAACAAGAAAGCCAAGACTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAGTTAGAAGGTTGTCAGTTGGTAAAGGTAGAAGGGAACAAGCTCTATGTCAAGCAGGAT
AATCAAGACCTGGCTTTTGGCCTTTCAAGTGCTACTGATTTTCGAAAAACAAATGCTGACGGTCGAGGCTACCAACCAAT
GCTTTTCAATGTAAAAGCTAGTACAATTAGTCAAAATAACCAGATAGTCACCATCCAAGTGACTCTTAAAAATGGGCTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

3D structure

• AlphaFold DB: A0A1V0GF29

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.156	97.241	0.566
comYF	Streptococcus mutans UA159	57.447	97.241	0.559
comGF/cglF	Streptococcus pneumoniae Rx1	50	97.931	0.49
comGF/cglF	Streptococcus pneumoniae D39	50	97.931	0.49
comGF/cglF	Streptococcus pneumoniae R6	50	97.931	0.49
comGF/cglF	Streptococcus pneumoniae TIGR4	50	97.931	0.49
comGF/cglF	Streptococcus mitis SK321	47.222	99.31	0.469
comGF/cglF	Streptococcus mitis NCTC 12261	47.222	99.31	0.469
comGF	Lactococcus lactis subsp. cremoris KW2	45.324	95.862	0.434