Detailed information    

insolico Bioinformatically predicted

Overview

Name   ssbB/cilA   Type   Machinery gene
Locus tag   R8559_RS09285 Genome accession   NZ_AP026926
Coordinates   1788750..1789145 (-) Length   131 a.a.
NCBI ID   WP_000282467.1    Uniprot ID   A0A098Z0L0
Organism   Streptococcus pneumoniae strain PZ900700119     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1782322..1808891 1788750..1789145 within 0
IScluster/Tn 1785230..1792711 1788750..1789145 within 0


Gene organization within MGE regions


Location: 1782322..1808891
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8559_RS09250 (PC0116_18190) - 1782322..1783098 (+) 777 WP_001086341.1 aminoglycoside 3'-phosphotransferase -
  R8559_RS09255 (PC0116_18200) recX 1783108..1783884 (+) 777 WP_000705114.1 recombination regulator RecX -
  R8559_RS09260 (PC0116_18210) - 1783973..1784506 (+) 534 WP_000775321.1 DUF402 domain-containing protein -
  R8559_RS11615 (PC0116_18220) - 1784864..1785070 (-) 207 WP_000775827.1 transcriptional regulator -
  R8559_RS09270 (PC0116_18230) - 1785230..1786459 (+) 1230 WP_000436324.1 ISL3 family transposase -
  R8559_RS09275 (PC0116_18240) groL 1786558..1788180 (-) 1623 WP_000031585.1 chaperonin GroEL -
  R8559_RS09280 (PC0116_18250) groES 1788196..1788480 (-) 285 WP_000917330.1 co-chaperone GroES -
  R8559_RS09285 (PC0116_18260) ssbB/cilA 1788750..1789145 (-) 396 WP_000282467.1 single-stranded DNA-binding protein Machinery gene
  R8559_RS09290 (PC0116_18270) - 1789223..1789984 (-) 762 WP_001107757.1 SDR family oxidoreductase -
  R8559_RS09295 (PC0116_18280) ytpR 1790017..1790643 (-) 627 WP_000578302.1 YtpR family tRNA-binding protein -
  R8559_RS09300 (PC0116_18290) - 1790659..1790976 (-) 318 WP_000615774.1 thioredoxin family protein -
  R8559_RS09305 (PC0116_18300) - 1790973..1791272 (-) 300 WP_001818001.1 DUF4651 domain-containing protein -
  R8559_RS09310 (PC0116_18310) - 1791455..1792711 (+) 1257 WP_000436627.1 ISL3 family transposase -
  R8559_RS09315 - 1792788..1792919 (+) 132 WP_001811306.1 hypothetical protein -
  R8559_RS09325 - 1793031..1793176 (-) 146 Protein_1827 cell wall-binding protein -
  R8559_RS09330 (PC0116_18320) - 1793388..1794062 (-) 675 WP_000725722.1 LiaF transmembrane domain-containing protein -
  R8559_RS09335 (PC0116_18330) - 1794068..1794514 (-) 447 WP_000776589.1 LytTR family DNA-binding domain-containing protein -
  R8559_RS09340 - 1794628..1795131 (-) 504 WP_000800939.1 phosphatase PAP2 family protein -
  R8559_RS09345 (PC0116_18340) - 1795128..1795490 (-) 363 WP_000078805.1 DUF2200 domain-containing protein -
  R8559_RS09350 (PC0116_18350) rcrQ 1795556..1796587 (-) 1032 WP_000346795.1 ABC transporter ATP-binding protein Regulator
  R8559_RS09355 (PC0116_18360) rcrP 1796594..1797415 (-) 822 WP_000601691.1 ABC transporter permease Regulator
  R8559_RS09360 (PC0116_18370) - 1797432..1797902 (-) 471 WP_000360532.1 MarR family winged helix-turn-helix transcriptional regulator -
  R8559_RS09365 (PC0116_18380) - 1798026..1798742 (-) 717 WP_000532874.1 YebC/PmpR family DNA-binding transcriptional regulator -
  R8559_RS09370 (PC0116_18390) ply 1799623..1801038 (-) 1416 WP_001284359.1 cholesterol-dependent cytolysin pneumolysin -
  R8559_RS09375 (PC0116_18400) - 1801049..1801459 (-) 411 WP_000595757.1 hypothetical protein -
  R8559_RS09380 (PC0116_18410) - 1801452..1802060 (-) 609 WP_000083614.1 hypothetical protein -
  R8559_RS09385 (PC0116_18420) - 1802073..1802531 (-) 459 WP_000186955.1 DUF4231 domain-containing protein -
  R8559_RS11620 (PC0116_18430) - 1802656..1802787 (+) 132 WP_000997307.1 hypothetical protein -
  R8559_RS09390 (PC0116_18440) - 1802765..1803055 (+) 291 Protein_1841 transposase family protein -
  R8559_RS09395 (PC0116_18450) - 1803532..1804365 (+) 834 WP_001842125.1 glycerophosphodiester phosphodiesterase family protein -
  R8559_RS09400 (PC0116_18460) - 1804400..1805461 (+) 1062 WP_000475762.1 extracellular solute-binding protein -
  R8559_RS09405 (PC0116_18470) - 1805478..1806482 (+) 1005 WP_000627602.1 ABC transporter ATP-binding protein -
  R8559_RS09410 (PC0116_18480) - 1806494..1808188 (+) 1695 WP_001232290.1 iron ABC transporter permease -
  R8559_RS09415 (PC0116_18490) - 1808190..1808891 (+) 702 WP_001054457.1 MgtC/SapB family protein -

Sequence

Protein


Download         Length: 131 a.a.        Molecular weight: 14925.89 Da        Isoelectric Point: 5.9409

>NTDB_id=98445 R8559_RS09285 WP_000282467.1 1788750..1789145(-) (ssbB/cilA) [Streptococcus pneumoniae strain PZ900700119]
MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGEREADFVNMVLWGRLAETLASYATKGSLISVDGELRTR
RFEKNGQMNYVTEVLVTGFQLLESRAQRAMRENNAGQDLADLVLEEEELPF

Nucleotide


Download         Length: 396 bp        

>NTDB_id=98445 R8559_RS09285 WP_000282467.1 1788750..1789145(-) (ssbB/cilA) [Streptococcus pneumoniae strain PZ900700119]
ATGTATAATAAAGTTATCATGATTGGGCGTTTAACGTCTACACCAGAATTGCACAAAACCAACAATGACAAGTCGGTAGC
GCGAGCAACTATCGCTGTGAACCGTCGTTACAAAGACCAAAACGGTGAACGTGAAGCTGATTTTGTCAATATGGTCCTAT
GGGGCAGACTAGCAGAAACTTTGGCAAGCTACGCAACCAAAGGTAGTCTCATTTCCGTTGATGGAGAATTGCGTACCCGT
CGCTTTGAGAAAAATGGCCAAATGAACTACGTGACCGAAGTACTTGTCACAGGATTCCAACTCTTGGAAAGTCGTGCTCA
ACGTGCTATGCGTGAAAATAATGCAGGCCAAGATTTGGCAGATTTGGTCTTGGAAGAGGAAGAATTGCCATTTTAA

Domains

Predicted by InterproScan.

Single-strand binding protein family (SSB)

(3-101)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098Z0L0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbB/cilA Streptococcus pneumoniae D39

100

100

1
  ssbB/cilA Streptococcus pneumoniae Rx1

100

100

1
  ssbB/cilA Streptococcus pneumoniae R6

100

100

1
  ssbB/cilA Streptococcus pneumoniae TIGR4

99.237

100

0.992
  ssbB/cilA Streptococcus mitis SK321

98.473

100

0.985
  ssbB/cilA Streptococcus mitis NCTC 12261

98.473

100

0.985
  ssbA Streptococcus mutans UA159

74.809

100

0.748
  ssbB Streptococcus sobrinus strain NIDR 6715-7

70.229

100

0.702
  ssbB Lactococcus lactis subsp. cremoris KW2

59.821

85.496

0.511
  ssbA Bacillus subtilis subsp. subtilis str. 168

50.943

80.916

0.412
  ssb Latilactobacillus sakei subsp. sakei 23K

46.903

86.26

0.405

Multiple sequence alignment