Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   PO855_RS09875 Genome accession   NZ_AP026721
Coordinates   1971156..1971431 (-) Length   91 a.a.
NCBI ID   WP_002356991.1    Uniprot ID   A0A1B4XPV0
Organism   Enterococcus faecalis strain SVR2330     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1966156..1976431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PO855_RS09840 (EfsSVR2330_19540) - 1966567..1967478 (-) 912 WP_271527040.1 hypothetical protein -
  PO855_RS09845 (EfsSVR2330_19550) - 1967479..1967763 (-) 285 WP_271527042.1 helix-turn-helix domain-containing protein -
  PO855_RS09850 (EfsSVR2330_19560) - 1967780..1968763 (-) 984 WP_271527044.1 DUF3991 domain-containing protein -
  PO855_RS09855 (EfsSVR2330_19570) - 1968836..1969708 (-) 873 WP_271527046.1 DUF6017 domain-containing protein -
  PO855_RS09860 (EfsSVR2330_19580) - 1969739..1970260 (-) 522 WP_416373208.1 DUF5720 family protein -
  PO855_RS09865 - 1970518..1970688 (+) 171 Protein_1922 tyrosine-type recombinase/integrase -
  PO855_RS09870 (EfsSVR2330_19590) comGD 1970716..1971159 (-) 444 WP_002369912.1 competence type IV pilus minor pilin ComGD -
  PO855_RS09875 (EfsSVR2330_19600) comGC/cglC 1971156..1971431 (-) 276 WP_002356991.1 competence type IV pilus major pilin ComGC Machinery gene
  PO855_RS09880 (EfsSVR2330_19610) comGB 1971431..1972477 (-) 1047 WP_002369171.1 competence type IV pilus assembly protein ComGB -
  PO855_RS09885 (EfsSVR2330_19620) comGA 1972434..1973402 (-) 969 WP_002369913.1 competence type IV pilus ATPase ComGA -
  PO855_RS09890 (EfsSVR2330_19630) - 1973642..1974970 (-) 1329 WP_002362058.1 APC family permease -
  PO855_RS09895 (EfsSVR2330_19640) rlmN 1975260..1976333 (-) 1074 WP_002356987.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -

Sequence

Protein


Download         Length: 91 a.a.        Molecular weight: 10464.41 Da        Isoelectric Point: 9.3192

>NTDB_id=96732 PO855_RS09875 WP_002356991.1 1971156..1971431(-) (comGC/cglC) [Enterococcus faecalis strain SVR2330]
MKKKQKYAGFTLLEMLIVLLIISVLILLFVPNLAKHKETVDKKGNEAIVKIVESQIELYTLEKNKTPSLNELVNEGYITK
EQLDKYTAEKQ

Nucleotide


Download         Length: 276 bp        

>NTDB_id=96732 PO855_RS09875 WP_002356991.1 1971156..1971431(-) (comGC/cglC) [Enterococcus faecalis strain SVR2330]
ATGAAAAAGAAACAAAAATACGCAGGGTTTACATTATTAGAAATGTTGATTGTCTTATTGATTATTTCCGTATTGATTTT
ACTTTTTGTTCCTAACTTAGCGAAACATAAAGAAACAGTTGATAAAAAAGGCAATGAAGCAATCGTAAAAATTGTAGAAT
CACAAATCGAGCTCTACACACTAGAAAAAAATAAGACGCCTTCTTTAAATGAATTAGTCAACGAAGGCTACATTACTAAA
GAGCAGTTAGATAAATATACAGCAGAAAAGCAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(5-28)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1B4XPV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae D39

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae R6

63.095

92.308

0.582
  comGC/cglC Streptococcus pneumoniae TIGR4

63.095

92.308

0.582
  comGC/cglC Streptococcus mitis NCTC 12261

61.905

92.308

0.571
  comGC/cglC Streptococcus mitis SK321

61.176

93.407

0.571
  comGC Lactococcus lactis subsp. cremoris KW2

58.14

94.505

0.549
  comYC Streptococcus gordonii str. Challis substr. CH1

56.322

95.604

0.538
  comYC Streptococcus suis isolate S10

52.326

94.505

0.495
  comYC Streptococcus mutans UA159

57.692

85.714

0.495
  comYC Streptococcus mutans UA140

57.692

85.714

0.495
  comGC Latilactobacillus sakei subsp. sakei 23K

46.154

100

0.462
  comGC Staphylococcus aureus MW2

46.835

86.813

0.407
  comGC Staphylococcus aureus N315

46.835

86.813

0.407
  comGC Bacillus subtilis subsp. subtilis str. 168

48.649

81.319

0.396

Multiple sequence alignment