Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   NSQ79_RS09565 Genome accession   NZ_CP150200
Coordinates   2045720..2046661 (-) Length   313 a.a.
NCBI ID   WP_002887018.1    Uniprot ID   A0AAW6D6G7
Organism   Streptococcus sp. FSL W7-1342     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2040720..2051661
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NSQ79_RS09525 (NSQ79_09525) - 2040795..2041988 (-) 1194 WP_138261572.1 acetate kinase -
  NSQ79_RS09530 (NSQ79_09530) comYH 2042045..2043001 (-) 957 WP_138261573.1 class I SAM-dependent methyltransferase Machinery gene
  NSQ79_RS09535 (NSQ79_09535) comGG 2043046..2043363 (-) 318 WP_021144683.1 competence type IV pilus minor pilin ComGG -
  NSQ79_RS09540 (NSQ79_09540) comYF 2043341..2043778 (-) 438 WP_045769383.1 competence type IV pilus minor pilin ComGF Machinery gene
  NSQ79_RS09545 (NSQ79_09545) comGE 2043765..2043995 (-) 231 WP_002887015.1 competence type IV pilus minor pilin ComGE -
  NSQ79_RS09550 (NSQ79_09550) comYD 2044027..2044455 (-) 429 WP_014632541.1 competence type IV pilus minor pilin ComGD Machinery gene
  NSQ79_RS09555 (NSQ79_09555) comYC 2044415..2044729 (-) 315 WP_037611125.1 competence type IV pilus major pilin ComGC Machinery gene
  NSQ79_RS09560 (NSQ79_09560) comYB 2044738..2045838 (-) 1101 WP_138261574.1 competence type IV pilus assembly protein ComGB Machinery gene
  NSQ79_RS09565 (NSQ79_09565) comGA/cglA/cilD 2045720..2046661 (-) 942 WP_002887018.1 competence type IV pilus ATPase ComGA Machinery gene
  NSQ79_RS09570 (NSQ79_09570) - 2046741..2047103 (-) 363 WP_049529260.1 DUF1033 family protein -
  NSQ79_RS09575 (NSQ79_09575) rpoC 2047266..2050904 (-) 3639 WP_002887020.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35283.31 Da        Isoelectric Point: 5.7041

>NTDB_id=966132 NSQ79_RS09565 WP_002887018.1 2045720..2046661(-) (comGA/cglA/cilD) [Streptococcus sp. FSL W7-1342]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGQRVSLRLSTVGDYRGLESLVIRVLHSERRELVYWNQGIQPIMDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSVAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSTSWNQQLEGLVKQGYLTEGDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=966132 NSQ79_RS09565 WP_002887018.1 2045720..2046661(-) (comGA/cglA/cilD) [Streptococcus sp. FSL W7-1342]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTACGAGCTCTATATGCGAGTTGGCCAGGAGAGGAGATTAATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTAGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTAGGTTCCTGTGACTATGAT
TGTGGTGATGGTCAAAGAGTTTCTCTGCGTTTGTCTACCGTTGGGGATTATCGTGGCTTAGAAAGTTTAGTTATTCGTGT
TCTACATTCCGAACGTCGAGAATTAGTGTACTGGAATCAAGGAATCCAGCCTATTATGGATGCTTTGGATTATCGTGGAT
TATATCTCTTTGCAGGTCCCGTTGGTTCTGGAAAGACTACGCTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTGATTTCGATTGAGGATCCTGTGGAAATTAAACAGGATAATGTTTTGCAACTTCAGGTGAATCAAGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCACTGCGTCACCGCCCGGATGTTTTGATTATTGGAGAAATTCGAGATAAGGAGA
CTGCTCGAGCGGTTATTAGAGCTAGTCTGACGGGAGTGACTGTTCTTTCAACTATTCACGCAAAGAGTGTGGCAGGTGTT
TATGAGCGTCTTCTGGACCTTGGTGTAGATAAGTCTGAGTTGGATAATGCCCTTCAAGGGATTGCCTACATGCGTCTGAT
TAAGGGAGGAGGTGTGATTGATTTTGCCAGTGAAAATTTCCAAAGTCATTCGTCAACCAGTTGGAACCAGCAGTTGGAAG
GCTTGGTTAAACAAGGATATCTCACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.916

99.361

0.655
  comYA Streptococcus mutans UA159

65.176

100

0.652
  comYA Streptococcus mutans UA140

65.176

100

0.652
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.63

99.361

0.642
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.897

99.681

0.607
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

41.697

86.581

0.361

Multiple sequence alignment