Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   V6U66_RS09945 Genome accession   NZ_CP145864
Coordinates   2111734..2112675 (-) Length   313 a.a.
NCBI ID   WP_155214001.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS7     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2106734..2117675
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U66_RS09905 (V6U66_09885) - 2106809..2108002 (-) 1194 WP_002885831.1 acetate kinase -
  V6U66_RS09910 (V6U66_09890) comYH 2108059..2109015 (-) 957 WP_014632544.1 class I SAM-dependent methyltransferase Machinery gene
  V6U66_RS09915 (V6U66_09895) comGG 2109060..2109377 (-) 318 WP_045001363.1 competence type IV pilus minor pilin ComGG -
  V6U66_RS09920 (V6U66_09900) comYF 2109355..2109792 (-) 438 WP_410534501.1 competence type IV pilus minor pilin ComGF Machinery gene
  V6U66_RS09925 (V6U66_09905) comGE 2109779..2110009 (-) 231 WP_013991265.1 competence type IV pilus minor pilin ComGE -
  V6U66_RS09930 (V6U66_09910) comYD 2110041..2110469 (-) 429 WP_014632541.1 competence type IV pilus minor pilin ComGD Machinery gene
  V6U66_RS09935 (V6U66_09915) comYC 2110429..2110755 (-) 327 WP_070576715.1 competence type IV pilus major pilin ComGC Machinery gene
  V6U66_RS09940 (V6U66_09920) comYB 2110752..2111852 (-) 1101 WP_155214000.1 competence type IV pilus assembly protein ComGB Machinery gene
  V6U66_RS09945 (V6U66_09925) comYA 2111734..2112675 (-) 942 WP_155214001.1 competence type IV pilus ATPase ComGA Machinery gene
  V6U66_RS09950 (V6U66_09930) - 2112755..2113117 (-) 363 WP_002887019.1 DUF1033 family protein -
  V6U66_RS09955 (V6U66_09935) rpoC 2113280..2116918 (-) 3639 WP_002887020.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35274.29 Da        Isoelectric Point: 5.9272

>NTDB_id=940612 V6U66_RS09945 WP_155214001.1 2111734..2112675(-) (comYA) [Streptococcus salivarius strain KSS7]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYLRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGQRVSLRLSTVGDYRGLESLVIRVLHSERRELVYWNQGIQPIMDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGH
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSVAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSTSWNQQLEGLVQQGYLTEGDIKGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=940612 V6U66_RS09945 WP_155214001.1 2111734..2112675(-) (comYA) [Streptococcus salivarius strain KSS7]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGATATCTATGTCATTCCACGTCA
GGATAATTATGAGCTCTATCTGCGAGTTGGCCAGGAGAGGAGATTAATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTAGGTTCCTGTGACTATGAT
TGTGGTGATGGTCAAAGGGTTTCTCTGCGTTTGTCTACCGTTGGGGATTATCGCGGCTTAGAAAGTTTAGTTATTCGGGT
TCTACATTCCGAACGTCGAGAATTAGTGTACTGGAATCAAGGAATCCAGCCTATTATGGATGCTTTGGATTATCGTGGAT
TATATCTCTTTGCAGGTCCCGTTGGTTCTGGAAAGACTACGCTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAT
CAGGTGATTTCGATTGAGGATCCTGTGGAAATTAAACAGGATAATGTTTTGCAACTTCAGGTGAATCAAGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCACTGCGTCACCGCCCGGATGTTTTGATTATTGGAGAAATTCGAGATAAGGAGA
CTGCTCGAGCGGTTATTAGAGCTAGTCTGACGGGAGTGACTGTTCTTTCAACTATTCACGCAAAGAGTGTGGCAGGTGTT
TATGAGCGTCTTCTGGACCTCGGTGTAGATAAGTCTGAGTTGGATAATGCCCTTCAAGGGATTGCCTATATGCGTTTGAT
TAAGGGAGGAGGTGTGATTGATTTTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAGCAGTTGGAAG
GCTTGGTTCAACAAGGATATCTCACTGAAGGGGATATCAAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

64.537

100

0.645
  comYA Streptococcus mutans UA140

64.537

100

0.645
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

99.361

0.645
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.666

99.361

0.633
  comYA Streptococcus gordonii str. Challis substr. CH1

62.3

100

0.623
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.218

99.681

0.61
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

41.697

86.581

0.361