Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   V6U65_RS09315 Genome accession   NZ_CP145863
Coordinates   2010085..2011026 (-) Length   313 a.a.
NCBI ID   WP_410532391.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS6     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2005085..2016026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U65_RS09275 (V6U65_09270) - 2005160..2006353 (-) 1194 WP_014635115.1 acetate kinase -
  V6U65_RS09280 (V6U65_09275) comYH 2006410..2007366 (-) 957 WP_002885753.1 class I SAM-dependent methyltransferase Machinery gene
  V6U65_RS09285 (V6U65_09280) comGG 2007411..2007728 (-) 318 WP_021144683.1 competence type IV pilus minor pilin ComGG -
  V6U65_RS09290 (V6U65_09285) comYF 2007706..2008143 (-) 438 WP_021144684.1 competence type IV pilus minor pilin ComGF Machinery gene
  V6U65_RS09295 (V6U65_09290) comGE 2008130..2008360 (-) 231 WP_002887015.1 competence type IV pilus minor pilin ComGE -
  V6U65_RS09300 (V6U65_09295) comYD 2008392..2008820 (-) 429 WP_254593949.1 competence type IV pilus minor pilin ComGD Machinery gene
  V6U65_RS09305 (V6U65_09300) comYC 2008780..2009094 (-) 315 WP_170314557.1 competence type IV pilus major pilin ComGC Machinery gene
  V6U65_RS09310 (V6U65_09305) comYB 2009103..2010203 (-) 1101 WP_410533115.1 competence type IV pilus assembly protein ComGB Machinery gene
  V6U65_RS09315 (V6U65_09310) comYA 2010085..2011026 (-) 942 WP_410532391.1 competence type IV pilus ATPase ComGA Machinery gene
  V6U65_RS09320 (V6U65_09315) - 2011106..2011468 (-) 363 WP_002885749.1 DUF1033 family protein -
  V6U65_RS09325 (V6U65_09320) rpoC 2011624..2015262 (-) 3639 WP_002887020.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35297.34 Da        Isoelectric Point: 5.7065

>NTDB_id=940541 V6U65_RS09315 WP_410532391.1 2010085..2011026(-) (comYA) [Streptococcus salivarius strain KSS6]
MVTEFAKEMIKNADSCGAQDIYVIPRQENYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGQRVSLRLSTVGDYRGLESLVIRVLHSERRELVYWNQGIQPIMDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAAIRASLTGVTVLSTIHAKSVSGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSISWNQQLEGLVKQGYLTEGDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=940541 V6U65_RS09315 WP_410532391.1 2010085..2011026(-) (comYA) [Streptococcus salivarius strain KSS6]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGAAAATTATGAGCTCTATATGCGAGTTGGCCAGGAGAGGAGATTAATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTAGGTTCCTGTGACTATGAT
TGTGGTGATGGTCAAAGGGTTTCTCTGCGTTTGTCTACCGTAGGGGATTATCGCGGCTTAGAAAGTTTAGTTATTCGTGT
TCTACATTCTGAACGTCGAGAATTAGTGTACTGGAATCAAGGAATCCAGCCTATTATGGATGCTTTGGATTATCGTGGCT
TATATCTCTTTGCAGGTCCCGTTGGTTCTGGAAAGACTACGCTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTGATTTCGATTGAGGATCCTGTGGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTGAATCAAGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCATTACGTCACCGCCCGGATGTTTTGATTATTGGAGAAATTCGAGATAAGGAGA
CTGCTCGAGCGGCTATTAGAGCTAGTCTGACAGGAGTGACTGTTCTTTCAACTATTCACGCAAAGAGTGTGTCAGGTGTT
TATGAGCGTCTTCTGGACCTTGGTGTAGATAAGTCCGAGTTGGATAATGCCCTTCAAGGGATTGCCTACATGCGTCTGAT
TAAGGGAGGAGGTGTGATTGATTTTGCCAGTGAAAATTTCCAAAGCCATTCGTCAATCAGCTGGAACCAGCAGTTGGAAG
GCTTGGTTAAACAAGGATATCTCACTGAAGGGGATATACAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

65.176

100

0.652
  comYA Streptococcus mutans UA140

65.176

100

0.652
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

99.361

0.645
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.987

99.361

0.636
  comYA Streptococcus gordonii str. Challis substr. CH1

61.981

100

0.62
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.577

99.681

0.604
  comGA Lactococcus lactis subsp. cremoris KW2

51.125

99.361

0.508