Detailed information NTG0940537

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: V6U65_RS09290
• Genome accession: NZ_CP145863
• Coordinates: 2007706..2008143 (-)
• Length: 145 a.a.
• NCBI ID: WP_021144684.1
• Uniprot ID: A0AAW6D9H3
• Organism: Streptococcus salivarius strain KSS6
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2002706..2013143

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U65_RS09255 (V6U65_09250)	-	2002745..2003407 (-)	663	WP_021144681.1	CPBP family intramembrane glutamic endopeptidase	-
V6U65_RS09260 (V6U65_09255)	-	2003520..2003966 (-)	447	WP_021144682.1	hypothetical protein	-
V6U65_RS09265 (V6U65_09260)	-	2004044..2004700 (-)	657	WP_410532390.1	CPBP family intramembrane glutamic endopeptidase	-
V6U65_RS09270 (V6U65_09265)	-	2004712..2004909 (-)	198	WP_014635114.1	helix-turn-helix transcriptional regulator	-
V6U65_RS09275 (V6U65_09270)	-	2005160..2006353 (-)	1194	WP_014635115.1	acetate kinase	-
V6U65_RS09280 (V6U65_09275)	comYH	2006410..2007366 (-)	957	WP_002885753.1	class I SAM-dependent methyltransferase	Machinery gene
V6U65_RS09285 (V6U65_09280)	comGG	2007411..2007728 (-)	318	WP_021144683.1	competence type IV pilus minor pilin ComGG	-
V6U65_RS09290 (V6U65_09285)	comYF	2007706..2008143 (-)	438	WP_021144684.1	competence type IV pilus minor pilin ComGF	Machinery gene
V6U65_RS09295 (V6U65_09290)	comGE	2008130..2008360 (-)	231	WP_002887015.1	competence type IV pilus minor pilin ComGE	-
V6U65_RS09300 (V6U65_09295)	comYD	2008392..2008820 (-)	429	WP_254593949.1	competence type IV pilus minor pilin ComGD	Machinery gene
V6U65_RS09305 (V6U65_09300)	comYC	2008780..2009094 (-)	315	WP_170314557.1	competence type IV pilus major pilin ComGC	Machinery gene
V6U65_RS09310 (V6U65_09305)	comYB	2009103..2010203 (-)	1101	WP_410533115.1	competence type IV pilus assembly protein ComGB	Machinery gene
V6U65_RS09315 (V6U65_09310)	comYA	2010085..2011026 (-)	942	WP_410532391.1	competence type IV pilus ATPase ComGA	Machinery gene
V6U65_RS09320 (V6U65_09315)	-	2011106..2011468 (-)	363	WP_002885749.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16229.70 Da
• Isoelectric Point: 9.0226

>NTDB_id=940537 V6U65_RS09290 WP_021144684.1 2007706..2008143(-) (comYF) [Streptococcus salivarius strain KSS6]
MSLNSKVRAFTLLECLVALLVIAGSIQVYQGLTTVLVSNVKQVKQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQDLAFGLSSATDFRKTNADGRGYQPMLFNVKSSTISQKSQIVTIQVTLKNGLQRSFVYAFEKTS

Nucleotide

• Length: 438 bp

>NTDB_id=940537 V6U65_RS09290 WP_021144684.1 2007706..2008143(-) (comYF) [Streptococcus salivarius strain KSS6]
ATGTCTCTCAATAGCAAGGTTCGTGCTTTTACCCTCTTGGAATGTCTAGTAGCTCTATTGGTGATTGCTGGTTCAATTCA
AGTTTATCAAGGTCTGACCACAGTATTGGTGAGCAATGTTAAGCAGGTCAAGCAACAAGAAAACCAAGACTGGCTCCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGTTGTCAGTTGGTAAAGGTAGAGGGGAACAAACTCTATGTCAAGCAGGAT
AATCAAGACTTAGCTTTTGGACTATCAAGTGCTACTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTACCAACCTAT
GCTTTTTAATGTAAAATCTAGTACGATAAGCCAAAAGAGCCAGATAGTCACCATCCAAGTGACTCTTAAAAATGGGCTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAAGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	56.738	97.241	0.552
comYF	Streptococcus mutans UA159	56.028	97.241	0.545
comGF/cglF	Streptococcus pneumoniae D39	50	97.931	0.49
comGF/cglF	Streptococcus pneumoniae Rx1	50	97.931	0.49
comGF/cglF	Streptococcus pneumoniae R6	50	97.931	0.49
comGF/cglF	Streptococcus pneumoniae TIGR4	50	97.931	0.49
comGF/cglF	Streptococcus mitis NCTC 12261	47.222	99.31	0.469
comGF/cglF	Streptococcus mitis SK321	47.222	99.31	0.469
comGF	Lactococcus lactis subsp. cremoris KW2	44.604	95.862	0.428